SUBJECT CODE
HOURS/WEEK
MARKS
CATEGORY
SEMESTER
CREDIT
PAPER
COURSE NAME L T P
TOTAL
ESE
CIA
CLINICAL
ELECTIVE
III ACMB3 GENERIC/DISCIPLINE LABORATORY 3 - - 3 3 25 75 100
SPECIFIC ELECTIVE - TECHNOLOGY
III
Course Objectives
CO1 Demonstrate ethical and professional conduct with patients, laboratory personnel, health- care
professionals, and the public.
CO2 Explain how accurate and reliable information might be obtained about proper procurement,
storage, and handling of laboratory specimens.
CO3 Develop a sound scientific knowledge foundation that prepares them to interpret, analyze and
evaluate scientific knowledge in clinical practice.
CO4 Perform a full range of laboratory tests with accuracy and precision.
CO5 Establish quality assurance principles and practices to ensure the accuracy and reliability of
laboratory information.
UNIT – I 12
Introduction to Clinical Laboratory Science: Basic laboratory principles - Code of conduct for
medical laboratory personnel -Organization of clinical laboratory and role of medical laboratory
technician - Safety measures. Assessment of a patient and brief history of collection. Maintenance of
Hygiene & Infection Control Practices.
UNIT – II 12
Specimen collection and processing - Blood, urine, stool, sputum CSF, amniotic fluid and bile.
Separation of serum and plasma, Handling of specimens for testing, preservation of specimens,
transport of specimens and factors affecting the clinical results.
UNIT – III 12
Introduction to histopathology-Methods of examination of tissues and cells, Fixation of tissues:
Classification and properties of fixatives. Tissue processing - Collection of specimens, Labeling and
fixation, Dehydration, Clearing, Impregnation, Embedding - Paraffin block making, Section Cutting,
Microtomes – types and mounting of sections.
UNIT – IV 12
Introduction to Haematology- Laboratory methods used in the investigation of coagulation disorders
- coagulation tests , Routine coagulation tests, (prothrombin time , plasma recalcification time,partial
thromboplastin time , activated partial thromboplastin time, thrombin time), Laboratory diagnosis of
bleeding disorders. Estimation of fibrinogen, Assay of coagulation factors.
UNIT – V 12
Quality Standards in Health Laboratories – Development and implementation of standards,
Accreditation Boards –NABL, ISO, CAP, COLA, Performing quality assessment - pre-analytical,
analytical, and post-analytical phases of testing.
Total 60
Course Outcomes
Course On completion of this course, students will;
Outcomes
CO1 Describe characteristics of laboratory organizations PO3, PO11
and demonstrate professionalism by displaying
professional conduct, model ethical behavior and
operate as a vital member of the medical lab team.
Practice safety or infection control procedures in the
clinical laboratory, properly use safety equipment
and maintain a clean, safe work environment.
CO2 Accurately collect specimens for various purposes. PO5, PO6, PO11
Determine appropriate tests based on test request,
Maintain standard and transmission-based
precautions, Engage in the scientific process by
understanding the principles and practices of clinical
study design, implementation, and dissemination of
results.
CO3 Identify the basic structure of cells, tissues and organs PO6, PO8, PO9, PO11
and describe their contribution to normal function.
Interpret light and electron microscopic histological
images and identify the tissue source and structures.
Relate and recognize the histological appearance of
affected tissues to the underlying pathology.
CO4 Recognize the pathologies behind benign and PO5, PO6, PO9, PO11
malignant disorders of erythrocytes, leucocytes,
thrombocytes and familiar with the diagnosis,
evaluation, and management of hematologic
malignancies.
CO5 Interpret, implement, and complying with laws, PO1,PO10
regulations and accrediting standards and guidelines
of relevant governmental and non-governmental
agencies.
TEXT BOOKS
1. Mukharji,K.L. (2000).Medical Laboratory Techniques, Vol - I, II & III, 5 th Edition. Tata
McGrawHill, Delhi.
2. Ochei,A., Kolhatkar.A. (2000).Medical Laboratory Science: Theory and Practice, McGraw Hill
Education.
3 RamnikSood (2015).Concise Book of Medical Laboratory Technology: Methods and
Interpretation, 2nd Edition, Jaypee Brothers Medical Publishers, NewDelhi.
4. S. Ramakrishnan, KN Sulochana(2012). Manual of Medical Laboratory Techniques,Jaypee
Brothers Medical Publishers Pvt. Ltd
5. Talib V.H. (2019).Handbook Medical Laboratory Technology, 2nd Edition, Directorate of health
services, Government of India.
REFERENCE BOOKS
1 Rutherford, B.H. Gradwohl , A.C. Sonnenwirth L. Jarett. Gradwohls. (2000). Clinical
Laboratory Methods and Diagnosis, Vol-I, 8th edition, Mosby.
2 Baker, F.J., Silverton, R.E., and Pallister,.J. (1998). An Introduction to Medical Laboratory
Technology, 7th Edition, CBS Publishers and Distributors Pvt. Ltd.
3 Godkar (2021).Textbook of Medical Laboratory Technology, 3rd Edition, Bhalani Publishing
House.
4 M.N.Chatterjee and RanaShinde.(2008). Textbook of Medical Biochemistry, 7th Edition, Jaypee
Brothers Medical Publishers Pvt. Limited.
5 James G Cappucino. and Natalie Sherman. (2016). Microbiology – A laboratory manual. (5th
Edition). The Benjamin publishing company. New York.
WEB RESOURCES
1 https://www.jaypeedigital.com › book
2 https://www.pdfdrive.com › wintrobes-clinical-hematology
3 https://currentprotocols.onlinelibrary.wiley.com/doi/pdf/10.1002/cpet.5
4 https://vlab.amrita.edu/index.php?sub=3&brch=272
5 https://nptel.ac.in/courses/102105087
METHODS OF EVALUATION
Continuous Internal Assessment Test
Internal Assignments
25 Marks
Evaluation Seminars
Attendance and Class Participation
External
End Semester Examination 75 Marks
Evaluation
Total 100 Marks
Methods of Assessment
Recall (K1) Simple definitions, MCQ, Recall steps, Concept definitions
Understand/
Comprehend MCQ, True/False, Short essays, Concept explanations, Short summary or overview
(K2)
Application Suggest idea/concept with examples, Suggest formulae, Solve problems, Observe,
(K3) Explain
Problem-solving questions, Finish a procedure in many steps, Differentiate between
Analyze (K4)
various ideas, Map knowledge
Evaluate (K5) Longer essay/ Evaluation essay, Critique or justify with pros and cons
Check knowledge in specific or offbeat situations, Discussion, Debating or
Create (K6)
Presentations
MAPPING WITH PROGRAMME OUTCOMES:
PO1 PO2 PO3 PO4 PO5 PO6 PO7 PO8 PO9 PO10 PO11
CO1 M S
CO2 M S S
CO3 S S S S
CO4 M S S S
CO5 M M
QUESTION PAPER PATTERN
SUBJECT : CLINICAL LABORATORY TECHNOLOGY
SUB. CODE : ACMB3
CONTINUOUS INTERNAL ASSESSMENT
Time : 1 Hours Max. Marks : 15
Section Description Marks BT Level
A 2 MCQs with 4 options 2X1=2 K1 & K2
B 1 question – either A or B type 1X3=3 K2, K3, K4
C Answer any 2 questions out of 3 questions (Open Choice) 2 X 5 =10 K2, K3, K4
Total Marks 15
END SEMESTER EXAMINATION
Time : 3 Hours Max. Marks : 75
Section Description Marks BT Level
10 MCQs with 4 options
A 10 X 1 = 10 K1 & K2
(2 questions from each unit)
5 questions – either A or B type K2, K3, K4
B 5 X 5 = 25
(1 set of questions from each unit) K5 & K6
C 5 questions – either A or B type 5 X 8 = 40 K2, K3, K4
(1 set of questions from each unit) K5 & K6
Total Marks 75
