GTR MCQS
GTR MCQS
d) The reunion of surrounding soft tissue and a root surface with preserved periodontal ligament tissue
e) The formation of new cementum with inserting collagen fibers on a root surface deprived of its
periodontal ligament tissue
Answer: b) Healing without restoration of the tooth-attachment apparatus and is often associated with
the formation of a long junctional epithelium.
Explanation: Guided tissue regeneration is a periodontal therapy that involves the use of a barrier
membrane to promote the growth of new bone and connective tissue. It is used to treat periodontal
defects and is characterized by healing without restoration of the tooth-attachment apparatus and is
often associated with the formation of a long junctional epithelium.
2. What is regeneration?
d) The reunion of surrounding soft tissue and a root surface with preserved periodontal ligament tissue
e) The formation of new cementum with inserting collagen fibers on a root surface deprived of its
periodontal ligament tissue
Answer: a) The reproduction or reconstitution of a lost or injured part of the body in such a way that the
architecture and function of the lost or injured tissues are completely restored.
Explanation: Regeneration is the process of reproducing or reconstituting a lost or injured part of the
body in such a way that the architecture and function of the lost or injured tissues are completely
restored. In the context of periodontics, regeneration refers to the restoration of the tooth-attachment
apparatus, including the formation of new cementum, periodontal ligament, and alveolar bone.
3. What is reattachment?
d) The reunion of surrounding soft tissue and a root surface with preserved periodontal ligament tissue
e) The formation of new cementum with inserting collagen fibers on a root surface deprived of its
periodontal ligament tissue
Answer: d) The reunion of surrounding soft tissue and a root surface with preserved periodontal
ligament tissue.
Explanation: Reattachment is the reunion of surrounding soft tissue and a root surface with preserved
periodontal ligament tissue. It is a type of healing that occurs after periodontal therapy and is
characterized by the restoration of the tooth-attachment apparatus.
d) The reunion of surrounding soft tissue and a root surface with preserved periodontal ligament tissue
e) The formation of new cementum with inserting collagen fibers on a root surface deprived of its
periodontal ligament tissue
Answer: e) The formation of new cementum with inserting collagen fibers on a root surface deprived of
its periodontal ligament tissue, whether or not this has occurred because of periodontal disease or by
mechanical means.
Explanation: New attachment is the formation of new cementum with inserting collagen fibers on a root
surface deprived of its periodontal ligament tissue, whether or not this has occurred because of
periodontal disease or by mechanical means. It is a type of healing that occurs after periodontal therapy
and is characterized by the restoration of the tooth-attachment apparatus.
5. Which type of cell repopulates the root surface after periodontal surgery and determines the nature
of the attachment that will form?
a) Epithelial cells
c) Bone cells
d) Periodontal cells
Explanation: The type of cell which repopulates the root surface after periodontal surgery determines
the nature of the attachment that will form. Epithelial cells are one of the types of cells that can
repopulate the root surface and play a critical role in periodontal wound healing.
Which of the following cells are involved in periodontal wound healing?
A) Epithelial cells
C) Bone cells
D) Periodontal cells
Explanation: Epithelial cells, gingival connective tissue cells, bone cells, and periodontal cells all play a
role in periodontal wound healing. The apical migration of epithelium can prevent periodontal ligament
cells from repopulating the root surface, which can reduce the gain in attachment. However, promoting
the proliferation of periodontal cells along the surface can lead to new connective tissue attachment.
Guided tissue regeneration involves the placement of a physical barrier to prevent apical migration of
gingival epithelial and connective tissue cells onto the root surface and facilitate the repopulation of
PDL cells, which contain progenitor cells required for the formation of bone, cementum, and PDL.
e) To prevent infection
Explanation: Barriers are used to selectively guide cell proliferation and tissue expansion within tissue
compartments during periodontal surgery.
e) To prevent infection
Answer: c) To regenerate lost periodontium.
Explanation: The regeneration of lost periodontium, specifically vertical defects, is one of the indications
for using a barrier in periodontal surgery.
e) To prevent infection
Explanation: Using a barrier in cases of very severe defects with minimal remaining periodontium is a
contraindication for periodontal surgery.
b) Physical barrier, Selectively guide cell proliferation and tissue expansion within tissue compartments
c) Biocompatibility, Cell exclusion, Space maintenance, Tissue integration, Ease of use, Biological
activity
e) Full thickness flap, scaling and removed granulation tissue, 11mm deep periodontal lesion,
Membrane placed, 3 months healing
Explanation: Barriers are classified based on their resorbability into first, second, and third generations.
a) Biocompatibility
b) Cell exclusion
c) Space maintenance
d) Tissue integration
e) Ease of use
Explanation: Tissue integration is one of the characteristics of a barrier, along with biocompatibility, cell
exclusion, space maintenance, ease of use, and biological activity.
Explanation: The content mentions the three generations of classification for barriers as nonresorbable,
resorbable, and resorbable with growth factor.
Explanation: The content mentions that nonresorbable barriers provide complete control over the time
of application.
a) Collagen
b) Dura mater
c) Poly(glycolic acid)
d) Polytetrafluoroethylene (PTFE)
e) Calcium Sulphate
Explanation: The content mentions that resorbable barriers do not require an additional surgery.
a) Collagen
b) Dura mater
c) Poly(glycolic acid)
d) Polytetrafluoroethylene (PTFE)
e) Calcium Sulphate
ve
3. Osteoinductive
1. Which material is composed of a bilayer collagen membrane with a smooth and rough layer?
A. PTFE
B. Geistlich Bio-Gide®
C. Bio-Gide
D. Bone Grafts
E. Grafting Materials
Explanation: Geistlich Bio-Gide® is a bilayer collagen membrane composed of a smooth and a rough
layer. The smooth upper layer is for the attachment of fibroblasts leading to a favorable healing of the
gingival tissue, while the dense porous layer is a guide for osteoblasts, thereby supporting optimal bone
healing.
2. Which material exhibits minimal inflammatory tissue reaction and has a porous microstructure of
solid nodes and fibrils?
A. PTFE
B. Geistlich Bio-Gide®
C. Bio-Gide
D. Bone Grafts
E. Grafting Materials
Answer: A. PTFE
Explanation: PTFE is a material that exhibits minimal inflammatory tissue reaction and has a porous
microstructure of solid nodes and fibrils. It is also mechanically identical to PTFE and can be subjected
to tensile stress.
3. Which material is highly adhesive, hydrophilic, and has high tensile and tear resistance?
A. PTFE
B. Geistlich Bio-Gide®
C. Bio-Gide
D. Bone Grafts
E. Grafting Materials
Answer: C. Bio-Gide
Explanation: Bio-Gide is a natural (porcine) material that is highly adhesive, hydrophilic, and has high
tensile and tear resistance. It also has excellent wound healing properties resulting from its good
vascularization and tissue integration.
4. Which type of bone grafting material stimulates the re-growth of alveolar bone and the formation of
new attachment through osteoconduction?
A. Osteoproliferative (osteogenetic)
B. Osteoconductive
C. Osteoinductive
Answer: B. Osteoconductive
Explanation: Osteoconductive bone grafting materials stimulate the re-growth of alveolar bone and the
formation of new attachment through osteoconduction, which is the formation of new bone on the
surface of the grafted material.
5. Which technique can be used to improve the stability of the augmented site when using a collagen
membrane?
E. No technique is needed
Explanation: When using a collagen membrane, a double layer technique can be used to improve the
stability of the augmented site. Applying a second membrane layer improves the stability of the site and
helps to avoid collapse of the membrane when combined with a bone substitute.
1. Which type of grafting material contributes to new bone formation by containing bone-forming cells?
a) Osteoproliferative (osteogenetic)
b) Osteoconductive
c) Osteoinductive
d) Allogeneic graft
e) Xenogeneic graft
Explanation: Osteoproliferative grafting materials contain bone-forming cells that contribute to the
formation of new bone.
2. Which type of grafting material serves as a scaffold for bone formation originating from adjacent host
bone?
a) Osteoproliferative (osteogenetic)
b) Osteoconductive
c) Osteoinductive
d) Autogenous graft
e) Alloplastic materials
Answer: b) Osteoconductive
Explanation: Osteoconductive grafting materials do not contribute to new bone formation per se but
serve as a scaffold for bone formation originating from adjacent host bone.
3. Which type of grafting material induces bone formation in the surrounding soft tissue immediately
adjacent to the grafted material?
a) Osteoproliferative (osteogenetic)
b) Osteoconductive
c) Osteoinductive
d) Xenogeneic graft
e) Alloplastic materials
Answer: c) Osteoinductive
Explanation: Osteoinductive grafting materials induce bone formation in the surrounding soft tissue
immediately adjacent to the grafted material.
4. Which type of grafting material is taken from the patient's own body?
a) Osteoproliferative (osteogenetic)
b) Osteoconductive
c) Osteoinductive
d) Allogeneic graft
e) Autogenous graft
Explanation: Autogenous grafting materials are taken from the patient's own body, such as edentulous
areas of the jaw, healing extraction sites, maxillary tuberosities, or the mandibular retromolar area.
5. Which type of grafting material is made from non-organic bovine bone matrix in an unchanged
inorganic form?
a) Xenogeneic graft
b) Allogeneic graft
c) Autogenous graft
d) Osteoconductive
e) Alloplastic materials
Explanation: Xenogeneic grafting materials are made from non-organic bovine bone matrix in an
unchanged inorganic form, such as Kielbone, Bio-Oss, Endobone, OsteoGraf, and Cerabone.
Which of the following materials is NOT an alloplastic material used for bone replacement grafts?
A) Tricalcium phosphate
B) Hydroxyapatite
C) Biogran
D) PerioGlas
Answer: E) Alloplastic materials are not used for bone replacement grafts.
Explanation: The passage discusses the use of alloplastic materials for bone replacement grafts,
including polymers such as HTR Synthetic Bone and bioceramics such as tricalcium phosphate and
hydroxyapatite, as well as bioactive glasses such as PerioGlas and Biogran. Therefore, option E is
incorrect as it contradicts the information provided in the passage.
A) Which type of defect has the highest predictability for successful surgical procedure?
Explanation: This type of defect has the highest predictability for successful surgical procedure
according to the content.
B) What type of defect has moderate predictability for successful surgical procedure?
Answer: B - Intra bony vertical defect > 4-5 mm measurable defect (2 and 3 wall defects).
Explanation: This type of defect has moderate predictability for successful surgical procedure according
to the content.
C) What type of defect has low predictability for successful surgical procedure?
Explanation: This type of defect has low predictability for successful surgical procedure according to the
content.
D) What type of defect has the least predictability for successful surgical procedure?
Explanation: This type of defect has the least predictability for successful surgical procedure according
to the content.
Explanation: e-PTFE membrane is suitable for intra bony defects according to the content.
1. Which of the following techniques can stimulate cell and vascular proliferation in the periodontal
ligament?
b) Increased vascularity
c) Scratching of the PDL
e) Suture material
Answer: c) Scratching of the PDL. Scratching the PDL can stimulate cell and vascular proliferation,
leading to improved healing and regeneration.
2. Which of the following is NOT a recommended step for selecting and placing ePTFE periodontal
material?
b) Choose a size that offers the most ideal design for defect coverage
e) The material should fit smoothly, avoiding folds, overlaps, and protrusions
Answer: d) Leave minimal overextension of defect margins. Enough material should be left to permit
lateral and interproximal suturing while leaving at least 3mm apical and lateral overextension of defect
margins.
3. Which of the following suture materials is NOT recommended for use in periodontal surgery?
a) Monofilament suture
b) Gortex suture
c) PDS II suture
d) Prolene suture
e) Silk suture
Answer: e) Silk suture. Silk sutures are not recommended for use in periodontal surgery due to their
braided nature, which can harbor bacteria and increase the risk of infection.
4. Which suturing technique is used to approximate material over the defect without engaging the flap
or tissue?
a) Sling suture
b) Interrupted suture
c) Continuous suture
b) To approximate material over the defect without engaging the flap or tissue
Answer: b) To approximate material over the defect without engaging the flap or tissue. Sling sutures
are used to hold the material in place over the defect without engaging the flap or tissue.
Answer: b) To avoid premature flap opening. Tight flap apposition is desired to avoid premature flap
opening and material exposure.
3. What is the ideal position of the flap margin in relation to the material in suturing techniques?
Answer: b) 2 to 3 mm coronal to the material. The flap margin should ideally be 2 to 3 mm coronal to
the material.
4. What is the recommended post-operative oral rinse for exposed material in suturing techniques?
a) 0.12% chlorhexidine gluconate for 5 days
Answer: b) 0.12% chlorhexidine gluconate for 10 days. Oral rinse containing 0.12% chlorhexidine
gluconate should be used for 10 days if the material becomes exposed, and should be used until
removal.
5. What is the recommended period for avoiding flossing and brushing at the treatment site in suturing
techniques?
a) 1 week
b) 2 weeks
c) 3 weeks
d) 4 weeks
e) 5 weeks
Answer: b) 2 weeks. Flossing and brushing at the treatment site should be avoided for at least two
weeks.
Note: The content provided in the question is incomplete and ends abruptly. Therefore, the last
question is not provided.
1. What is the recommended action if any complication develops during a regenerative procedure?
d) Emdogain
Answer: d) Emdogain
Explanation: Emdogain is not a growth factor, but a regenerative material used in periodontal
regeneration.
3. What is the main disadvantage of topical delivery of growth factors to periodontal wounds?
a) It is too expensive
b) It is not effective
c) It is difficult to apply
Explanation: Topical delivery of growth factors to periodontal wounds has shown promise, but it tends
to suffer from instability and quick dilution due to proteolytic breakdown, receptor-mediated
endocytosis, and solubility of the delivery vehicle.
Explanation: Platelet-derived growth factor (PDGF) exerts its biologic effects on cell proliferation,
migration, ECM synthesis, and antiapoptosis.
Explanation: Bone Morphogenetic Protein (BMP) is a protein belonging to the TGF-β1 superfamily with
the ability to induce bone formation.
c) It has the ability to stimulate intramembranous bone formation without an endochondral intermediate
Answer: c) It has the ability to stimulate intramembranous bone formation without an endochondral
intermediate.
Explanation: BMP is a protein belonging to the TGF-β1 superfamily and has the ability to induce bone
formation. It also has the ability to effect pluripotential cells to commit to an osteoblastic pathway.
However, it does not have the ability to induce cartilage formation.
a) Amelogenins
c) Amelotin
d) Tuftelin
e) Collagen
Answer: e) Collagen
Explanation: Enamel Matrix Proteins (EMP) are associated with amelogenesis and are synthesized and
secreted by ameloblasts. The EMP include amelogenins, ameloblastin (aka amelin or sheathlin),
amelotin, tuftelin, and enamelin. Collagen is not an EMP.
3. What is Emdogain?
c) A type of collagen
d) A type of cementum
e) A type of dentin
Explanation: Emdogain is a carrier for enamel matrix proteins and contains a 6% w/w propylene glycol
alginate, purified acid extract of porcine origin, and a mixture of EMP, mainly amelogenin. It is clinically
used for periodontal regeneration, root coverage, and root replantation. It has also been experimentally
used for dentin repair and tooth movement.
4. What is the biological concept behind the use of Emdogain for periodontal regeneration?
a) EMP mimics events that took place during the development of the periodontal tissues
Answer: a) EMP mimics events that took place during the development of the periodontal tissues
Explanation: The biological concept behind the use of Emdogain for periodontal regeneration is that
EMP mimics events that took place during the development of the periodontal tissues. This is based on
the finding that the cells of the Hertwigs epithelial root sheath deposit enamel matrix proteins on the
root surface prior to cementum formation and that these proteins are the initiating factor for the
formation of cementum. Emdogain can regenerate acellular extrinsic fiber cementum.
a) Tooth whitening
d) Orthodontic treatment
Explanation: Tum Emdogain is a clinically used product for periodontal regeneration, root coverage and
root replantation.
2. What is the use of human oral mucosa equivalent membrane (EVPOME) placed on a cadaveric
dermal carrier (Alloderm®)?
a) Tooth whitening
c) Periodontal regeneration
d) Orthodontic treatment
Explanation: For large soft tissue defects, a human oral mucosa equivalent membrane, made of
autogenous keratinocytes (EVPOME) placed on a cadaveric dermal carrier (Alloderm®) is used for
periodontal regeneration.
3. What is the concentration of multipotential stromal cells (MSCs) in a commercially available cellular
bone allograft?
b) It contains cells with cell surface markers called cluster differentiation (CD) markers that are found
with immunotyping of osteoprogenitor cells and osteoblasts
Answer: b) It contains cells with cell surface markers called cluster differentiation (CD) markers that are
found with immunotyping of osteoprogenitor cells and osteoblasts
Explanation: The commercially available cellular bone allograft contains cells with cell surface markers
called cluster differentiation (CD) markers that are found with immunotyping of osteoprogenitor cells
and osteoblasts.
Explanation: Gene therapy may achieve greater bioavailability of growth factors within periodontal
wounds and thus provide greater regenerative potential.
a) It is expensive
b) It is not effective
c) It is difficult to administer
Explanation: Gene transfer methods may circumvent many of the limitations with protein delivery to soft
tissue wounds, as protein delivery has limited bioavailability within periodontal wounds.
a) Open-ended
b) Multiple choice
c) True or false
d) Essay
Answer: d) Essay
Explanation: While open-ended, multiple choice, and true or false questions are all common types of
questions, essay questions require a more detailed and subjective response.
Explanation: Multiple choice questions are designed to assess a student's comprehension of a topic by
presenting them with several possible answers to choose from.
3. Which of the following is a common strategy for answering multiple choice questions?
a) Guessing randomly
Explanation: When faced with a multiple choice question, it is often helpful to eliminate answers that are
clearly incorrect, which can increase the chances of selecting the correct answer.
Answer: c) Make sure each question has only one correct answer
Explanation: Effective multiple choice questions should have a clear and unambiguous correct answer,
which can help ensure that students are being tested on their knowledge and understanding of the
topic.
Explanation: While multiple choice questions can be a useful tool for testing knowledge and
understanding, they also have potential drawbacks, such as being time-consuming to create, not
accurately assessing understanding, being too easy to guess on, and not being suitable for all types of
content.