GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Engineering
                                         Subject Code: 3160303
                                             Semester – VI
                                      Therapeutic Instrumentation
Type of course: Professional Core Course
Prerequisite: Basic electronics, Human Anatomy and Physiology, Biopotential Measurement &
              Techniques.
Rationale: To impart in students detailed knowledge about various therapeutic equipment and familiarize
            students with their basic working principle, instrumentation, clinical significance and
            advancements.
    Teaching Scheme        Credits                   Examination Marks                                 Total
                                           Theory Marks             Practical Marks                    Marks
L          T        P         C
                                       ESE (E)     PA (M)         ESE (V)        PA (I)
3          0        2         4           70                30             30               20           150
Content:
 Sr.     Contents                                                                           Total         %
 No.                                                                                         Hrs       Weightage
         Cardiac Pacemakers: Types of Pacemakers: External pacemakers and
         implantable pacemakers, Codes for Pacemakers, Packaging of implantable
         pacemakers, power sources of implantable pacemaker, Types of leads and
    1    electrodes of pacemakers.                                                           09           20%
         Cardiac Defibrillators: Needs of DC defibrillator, DC defibrillator, types of
         electrodes, Advisory External defibrillator (AED), Implantable defibrillator,
         Pacer-cardioverter-defibrillator, Defibrillator Analyzer.
         Haemodialysis Machines: Principle of Artificial Kidney, Types of Dialyzers,
    2    Performance analysis of Dialyzers, Membranes for Haemodialysis,                     07           15%
         Haemodialysis machine with various monitoring circuits.
         Instruments for Surgery: Principle, Techniques of Electrosurgical Diathermy,
         Electrosurgical diathermy machine, electrodes, Safety aspects of Electrosurgical
         Diathermy.
    3    Heart Lung Machine: Structure and function of heart lung machine, Study of          08           20%
         various components of Heart lung machine.
         Various types of Catheters, Working operation of Stents, Intra-aortic balloon
         pump (IABP).
         Physiotherapy and Electrotherapy Equipment: High frequency Heat therapy,
         Shortwave Diathermy, Microwave Diathermy, Ultrasound therapy,
    4    Electrotherapy, Muscle stimulator, Transcutaneous electrical nerve stimulation      09           20%
         (TENS), Functional Electrical Stimulation (FES), Deep brain stimulation, Vagus
         nerve stimulation.
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                                               w.e.f. AY 2019-20
                       GUJARAT TECHNOLOGICAL UNIVERSITY
                                             Bachelor of Engineering
                                              Subject Code: 3160303
          Anesthesia Machine: Need of Anesthesia, Anesthesia machine: Gas supply
          system, Vapour Delivery, Delivery system, Humidification, Patient Circuit.
          Ventilators: Artificial ventilation, ventilator terms and its types, modes of
          ventilators, classification of ventilators, pressure volume flow and time diagrams.
      5                                                                                         12         25%
          Microprocessor controlled ventilator, high frequency ventilators, humidifiers,
          nebulizers, aspirators.
          Drug delivery System: Infusion Pump, Syringe Pump, Insulin Pump.
          Construction and working of Baby Incubator.
                                                                                       Total    45         100%
Suggested Specification table with Marks (Theory):
 Distribution of Theory Marks
      R Level            U Level           A Level             N Level         E Level          C Level
       15%                25%               25%                 15%             10%              10%
Legends: R: Remembrance; U: Understanding; A: Application, N: Analyze and E: Evaluate C:
Create and above Levels (Revised Bloom’s Taxonomy)
Note: This specification table shall be treated as a general guideline for students and teachers. The actual
distribution of marks in the question paper may vary slightly from above table.
Reference Books:
   1. R. S. Khandpur “Handbook of Bio-Medical Instrumentation”, Tata McGraw Hill.
   2. Carr & Brown, “Introduction to Biomedical Equipment Technology” Pearson Education, Asia.
   3. Medical Instrumentation, Application and Design: J G. Webster. (John Wiley).
   4. Encyclopedia of Medical Devices and Instrumentation: J G. Webster. Vol I- VI (PH Pub).
   5. Springer handbook of medical technology : Rüdiger Kramme, Klaus-Peter Hoffmann, Robert Steven
      Pozos, Springer Science & Business Media.
   6. Joseph Bronzino, “Biomedical Engineering and Instrumentation”, PWS Engg ,Boston.
   7. Leslie Cromwell, “Biomedical Instrumentation and Measurements”.
Course Outcomes:
After learning this subject, students will be able to:
Sr.       CO statement                                                                           Marks %
No.                                                                                              weightage
CO-1      Explain working principle, design, operating and necessary instrumentation of
                                                                                                     20%
          Cardiac Pacemakers and Cardiac Defibrillators.
CO-2      Understand working principle, performance analysis, operating and various                  15%
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                                                 w.e.f. AY 2019-20
                     GUJARAT TECHNOLOGICAL UNIVERSITY
                                          Bachelor of Engineering
                                           Subject Code: 3160303
         monitoring circuit of Haemodialysis Machine.
CO-3     Describe working principle, design, operating and instrumentation of
                                                                                                 20%
         Electrosurgical Unit, catheters, stents and Intra-aortic balloon pump.
CO-4     Explain working principle, design, operating and instrumentation of Physiotherapy
                                                                                                 20%
         and Electrotherapy equipments.
CO-5     Illustrate working principle, design, operating and instrumentation of Anaesthesia
                                                                                                 25%
         machine, Ventilators, drug delivery devices, and Baby incubator.
List of Experiments:
Sr.    Name of Experiments                                                                    Duration
No.                                                                                           (Hours)
 1.    To study about different types of Pacemakers.                                             2
 2.    To study about different types of Defibrillator along with its electrode and                2
       instrumentation system.
 3.    To study about Haemodialysis Machine.                                                       2
 4.    To study about Electrosurgical Unit with its different modes.                               2
 5.    To study about Heart Lung machine and Intra-aortic balloon pump (IABP) .                    2
 6.    To study about Short Wave Diathermy.                                                        2
 7.    To study about Microwave and Ultrasound Diathermy.                                          2
 8.    To study about Transcutaneous electrical nerve stimulation (TENS) and Muscle                2
       Stimulator.
 9.    To study about Anesthesia Machine.                                                          2
10.    To study about Ventilator.                                                                  2
11.    To study about Infusion Pump and Syringe Pump.                                              2
Major Equipment: Biomedical Trainer and demo kit
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