5.
Reproduction
     3ºESO
How can we adapt to different
      environments?
1 Human reproduction
1.1 Characteristics of human reproduction
Humans reproduce sexually thanks to the gametes→ male and female
reproductive systems
●    Procesess
1.   Gamete formation
2.   Fertilisation
3.   embryonic development
4.   Birth
1. Gamete formation
● Human are unisexual→ each type of gamete is produced by a
  particular sex.
● We can also appreciate sexual dimorphism→ physical
  differences between the two sexes
● Gametes contain half of the genetic information (23
  chromosomes) of each progenitor
      ■   Ova→ female
      ■   Espermatozoa→ male
2. Fertilisation
Is the union of the gametes→ form the zygote
Happen in the female reproductive system
3. Embryonic development
It is the complete development of the zygote
inside the mothers body.
4. Birth
The development has been completed→
leaves the mothers body and develops the
vital functions by itself
1.2 Sexual maturity
●   When an individual is born has the main characteristics asociated with a
    particular sex (chromosomes) but the maturity of the organs happen
    later in life.
●   During puberty the levels of sexual hormones increase→ sexual and
    reproductive abilities
●   Which are the hormones
    that regulate the
    development of sexual
    characteristics?
●   Why do you think men tend
    to develop greater muscles
    in adulthood? Why their
    voice changes?
●   Why women tend to develop
    greater amount of body fat
    and widen the hips?
2. reproductive system
2.1 The male reproductive system
    The main goal→ introduce the
    spermatozoa into the female
    reproductive system
    Parts:
         ●   Testes
         ●   Reproductive tract
         ●   Penis
         ●   Glands
Testes:
●   Are the male gonads
●   Are located outside of the
    abdominal cavity covered by
    scrotum.
●   They are also endocrine glands→
    male sex hormones
●   Each one is composed by→
    seminiferous tubules where
    spermatozoa is produced
The reproductive tract
●   The epididymis: is a tube
    situated in the upper part of the
    testicles. The tubules of the testes
    converge there an is where the
    spermatozoa are stored.
●   The vasa deferentia→ connect
    the epididymis with the urethra
●   the urethra→ semen and urine
    leave the body
Penis
●   Through penetration the spermatozoa is deposited in the female organ.
●   The end is wider and is known as glans. Is protected by the foreskin.
Accessory glands:
Release secretions into vasa deferentia joining spermatozoa and forming
semen.
●   Seminal vesicles→ release nutrients for sperm
●   Prostate gland→ motility of sperm
●   Cowper´s gland→ lubricating secretion that neutralises acidity in uretra
    and vagina
2.2 The female reproductive system
The function of the reproductive system in female:
●    Contact between the ova and spermatozoa.
●    Feed and protect the embryo
●    Give birth
     Parts:
1.   Ovaries
2.   Female reproductive tract
3.   Vulva
Main parts of the female reproductive system
1.   The ovaries: are the female
     gonads
      ● Located in the pelvic
         areas.
      ● Certain amount of ova
         since the birth.
      ● They act as a endocrine
         system as well→
         oestrogen/progesterone
2. The female reproductive tract
     The fallopian tubes→ 2 tubes that connects the
     ovary→ uterus. The inside part of the tubes are ciliated
     cells→ directs the ova to the uterus.
     Uterus
       ●   Size and shape of a pear
       ●   Two layers→ External: muscular and thick wall
       ●   Internal→ epithelial layer→ endometrium. The
           embryo attaches to this layer after fertilisation
     Cervix→ lower part of the uterus which connect with
     the vagina
     The vagina→ flexible walls connect the uterus with the
     external environment.
3. The vulva→ two fold of skin called labia
Activity: sexual dimorphism
●   What is sexual dimorphism?
●   When does the development of sexual
    characteristics begin in humans?
●   Which hormonal/endocrine axis
    regulates sexual maturity?
●   Testosterone and estrogen can only be
    found in male/female respectively?
●   What are aromatase and 5-alfa
    reductase and why are key in sexual
    development?
3. Human Gametes
● Gametes are the cells responsibles for the
  human reproduction:
● Spermatozoa (male) → formed in the
  testis, half of the genetic information of
  human being(23 chromosomes)
● Ova (female) → formed in the ovary, half of
  the genetic information of the specie (23
  chromosomes)
3.1 Spermatozoa
Spermatozoa, main characteristics:
●   Formed in the seminiferous
    tubules in the testis
●   The process that created is a
    meiosis called→
    spermatogenesis
Parts:
●   Head→ the nucleus (genetic
    information)
●   Middle piece→ mitochondria→
    releases energy→ movement of
    the tail
●   The tail→ long flagellum
Spermatogenesis:
Produced in the walls of the seminiferous tubules→ constant meiotic
divisions that form sperm throughout the lifespan.
     3.2 Ova
 ●   Female gametes that are formed in the ovaries→
     oogenesis
 ●   Immobile cells which contains nutritious substances →
     embryo
Main parts:
 ●   Nucleus→ half of the genetic information of the specie (23
     chromosomes in human beings)
 ●   Cytoplasm→ vitelline membrane (nutrients), first stages of
     the embryo
 ●   The membrane, covered by two layers
 ●   Zona pellucida and corona radiata→ attracts the sperm,
     block secondary fecundation
Ovogenesis:
Ova are form in the ovaries in the
uterine period (while still a fetus) but
they are immature.
During puberty ova begin to mature
cyclically→ release of a mature ova
monthly → breaks the follicles
     4.1 The ovarian cycle
 ●    Growth of the follicles                 ●    Ovulation                            ●    Corpus luteum
      (Day 1-14)                                   (Day14+-)                                 (Day 14-28)
the hypophysis releases FSH (Follicles       one of the follicles gets fully mature→   forming the corpus luteum that
Stimulating Hormone) → maturity of           release a ovum. High levels of FSH and    releases oestrogen and progesterone
the ova inside the follicles. Oestrogen is   LH                                        → prepare the uterus for the embryo. If
also released in this stage                                                            it is not fertilised→ restart the cycle
   4.1 Uterine cycle
      Menstruation                  Growth of                       Secretory phase
                                    endometrium
      Day 1-5                                                       Day 15-28
                                    Day6-14
The surface of the           Starts right after the end of   If the ova is fertilised the corpus
endometrio is expelled out   menstruation.                   luteum→ hormones that sustain
of the body→ vagina                                          the endometrium→ embryonic
                             Regrowth of the                 development
It is known as the period,   endometrium
and is related to the
degeneration of the corpus
luteum
Activity: sexual hormones and health
Sex hormones play a key role in sexual
development. This requires proper nutrition and
lifestyle habits,
Research:
 ●   What is the precursor molecule of sex
     hormones.
 ●   What foods are harmful to the correct
     formation of sex hormones.
 ●   What are the long-term effects of consuming
     steroids?
 ●   How does the "day after" pill work and what
     effect does it have on hormonal balance?
5. Fertilisation pregnancy and birth
5.1 Fertilisation and embryonic development
●   Fertilisation→ union of the ova and the sperm to form a zygote.
●   The process occurs in the fallopian tubes → directed to the uterus.
●   Embryonic development→ developmental period since the zygote is
    formed until birth.
1.   After fertilisation the zygote travels to the uterus.
2.   The first cell divisions happen in this trip, the zygote is now known as
     embryo.
3.   When the embryo reaches the endometrium (inner part of the uterus)
     → implantation
Once the implantation take place:
 -   Development of placenta → organ that provides nutrients and
     exchange of waste with the mother → umbilical cord.
 -   Amnion→ sac filled with amniotic fluid→ protects the embryo
Development of the embryo
1t trimester → development of the organs, including the brain that starts its
formation around day 18→ we call it foetus
2nd trimester → the skeleton ossifies and the nervous system matures→ first
neural reflexes. Ex: first senses→ hearing 18 weeks
3rd trimester → growth and maturity of the organs. Lungs become functional
Labour and Birth
After 40 weeks of gestation (9 complete months) →
birth. Steps:
 -   The pituitary/hypophysis of the mother release
     oxytocin→ contraction of the uterus→ labour
 -   Labour main stages:
      -   Dilatation: expansion of the cervix so the child can get out.
          In this stage the amniotic sac breaks.
      -   Expulsion: contraction are more frequent and regular→
          expulsion of the baby. Cut umbilical cord→ lung stimulation
      -   Afterbirth: detach the placenta and expel it from the body.
6. Birth control
There are many ways in order to prevent undesired
conception:
●   Physical barriers→ prevents not only conception but the
    transmission of many other illnesses like Hepatitis→
    condoms/diaphragm
●   Chemical methods→ the pill/ day after pills/ spermicides
●   Surgical methods→ vasectomy/ tubal ligation
STI: sexually transmited illnesses
●   Some of this illnesses can be caused by
    bacteria→ chlamydia, gonorrhoea,
    syphilis (can cause death and
    neurological damages)
●   Some can be caused by viruses→
    herpes (blisters in the genitals), AIDS
    (immunosupression), HPV
    (papillomavirus→ uterine cancer)
DEBATE
Divide the class into 4 groups:
Research arguments in the following areas:
       ● Genetic engineering in agriculture.
       ● Genetic engineering and farming
       ● Genetic engineering and health
       ● Genetic engineering and vaccines
1.   Each group should research on one of the points
     and defend its project as an advantageous
     advance for society;
2.   Each group has to find also the weaknesses and
     problems derived from the rest of the topics.
3.   The winner will be the group that better defend
     itself against the counterarguments of the class
Debate- aborto
Anticonceptivos orales y efecto largo plazo
hepatitis cancer cuello utero
Estres y reaccion emocional en os organos reproductores
Aborto expontaneo y presencia de machos no dominantes→ bruce effect
ingenieria genetica bebes de diseño
madurez pulmonar
antojos del embarazo
Ritos animales → placenta
CRISPR
Clonación