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INTRODUCTION TO YOUR REPORT
ABOUT THIS REPORT
What is the purpose of this report?
What is included in your report?
What are the limitations of this report?
How is the report organised?
THE SCIENCE BEHIND THIS REPORT
From your cheek sample to your report: a journey through science and
evidence
What is genetics and genetic testing?
So, how can your genes and your weight be related?
NOW ENJOY YOUR PERSONALISED DIET REPORT!
Things to consider
WEIGHT MANAGEMENT
FTO GENE
MTIF3 GENE
PPARG GENE
ADIPOQ GENE
LIPID PROFILE *
APOA5 GENE
LIPC GENE
FADS1 GENE
WEIGHT, APPETITE & OBESITY - FTO
About the gene
BODY SIZE AND WEIGHT REGAIN - MTIF3
About the gene
FAT STORAGE - PPARG
About the gene
FAT BURNING - ADIPOQ
About the gene
TRIGLYCERIDE LEVELS - APOA5
About the gene
CHOLESTEROL AND TRIGLYCERIDE LEVELS - LIPC
About the gene
FATTY ACIDS PROCESSING - FADS1
About the gene
UNDERSTANDING THE HEALTHCARE PROFESSIONAL REPORT
EVIDENCE RATING SYSTEM
FTO GENE rs9939609 and rs1558902
evidence rating for risk
evidence rating for diet
References
MTIF3 gene rs4771122 and rs1885988 evidence rating for
risk
evidence rating for
diet
References
PPARG gene rs1801282 evidence rating for
risk
evidence rating for
diet
References
ADIPOQ gene rs1501299 evidence rating for risk
evidence rating for diet
References
• Lu JF, Zhou Y, Huang GH, Jiang HX, Hu BL, Qin SY. Association of ADIPOQ polymorphisms with obesity risk: a meta-analysis. Hum Immunol 2014;
75(10): 1062-8.
• Gao M, Ding D, Huang J, Qu Y, Wang Y, Huang Q. Association of genetic variants in the adiponectin gene with metabolic
syndrome: a case-control study and a systematic meta-analysis in the Chinese population. PLoS One 2013; 8(4): e58412.
• Hara K, Boutin P, Mori Y, et al. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the
Japanese population. Diabetes 2002; 51(2): 536-40.
• Shin MJ, Jang Y, Koh SJ, et al. The association of SNP276G>T at adiponectin gene with circulating adiponectin and insulin
resistance in response to mild weight loss. Int J Obes (Lond) 2006; 30(12): 1702- 8.
• Mente A, Razak F, Blankenberg S, et al. Ethnic variation in adiponectin and leptin levels and their association with adiposity and insulin
resistance. Diabetes Care 2010; 33(7): 1629-34.
• Cheung CY, Hui EY, Cheung BM, et al. Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study. Eur J
Endocrinol 2014; 171(1): 107-15.
• Reis CE, Bressan J, Alfenas RC. Effect of the diet components on adiponectin levels. Nutr Hosp 2010; 25(6): 881-8.
• Yu N, Ruan Y, Gao X, Sun J. Systematic Review and Meta-Analysis of Randomized, Controlled Trials on the Effect of Exercise
on Serum Leptin and Adiponectin in Overweight and Obese Individuals. Horm Metab Res 2017; 49(3): 164-73.
APOA5 gene rs662799 evidence rating
for risk
evidence rating for diet
References
4.
LIPC GENE rs1800588 evidence rating for risk
evidence rating for diet
References
FADS1 GENE rs174546 evidence rating
for risk
evidence rating for diet
References
GENETIC RESULT SUMMARY
GENE GENOTYPE PREDICTED FUNCTION
FTO
MTIF3
PPARG
ADIPOQ
APOA5
LIPC
FADS1
