INSTITUTE OF PHARMACEUTICAL SCIENCES

J.S. UNIVERSITY
B.PHARM 2ND SEMESTER (BIOCHEMISTERY)

QUIZ QUESTIONS
UNIT- I

1. A drug which prevents uric acid

8. Which are the cholesterol esters that
synthesis by inhibiting the enzyme
enter cells through the receptor-
xanthine oxidase is mediated endocytosis of lipoproteins
(A) Aspirin (B) Allopurinol hydrolyzed?
(C) Colchicine (D) Probenecid (A) Endoplasmin reticulum
2. Which of the following is required for (B) Lysosomes
crystallization and storage of the (C) Plasma membrane receptor
hormone insulin? (D) Mitochondria
(A) Mn++ (B) Mg++ 9. Which of the following phospholipids
(C) Ca++ (D) Zn++ is localized to a greater extent in the
outer leaflet of the membrane lipid
3. Oxidation of which substance in the body bilayer?
yields the most calories
(A) Choline phosphoglycerides
(A) Glucose (B) Glycogen
(B) Ethanolamine phosphoglycerides
(C) Protein (D) Lipids
(C) Inositol phosphoglycerides
4. Milk is deficient in which vitamins? (D) Serine phosphoglycerides
(A) Vitamin C (B) Vitamin A 10. All the following processes occur rapidly
(C) Vitamin B2 (D) Vitamin K in the membrane lipid bilayer except
5. Milk is deficient of which mineral? (A) Flexing of fatty acyl chains
(A) Phosphorus (B) Sodium (B) Lateral diffusion of phospholipids
(C) Transbilayer diffusion of phopholipids
(C) Iron (D) Potassium
(D) Rotation of phospholipids around their long
6. Synthesis of prostaglandinsis is inhibited axes
by
(A) Aspirin (B) Arsenic
(C) Fluoride (D) Cyanide
7. HDL is synthesized and secreted from
(A) Pancreas (B) Liver
(C) Kidney (D) Muscle
 UNIT- II

1. The constituent unit of inulin is

6. A polymer of glucose synthesized by the
(A) Glucose (B) Fructose action of leuconostoc mesenteroids in
(C) Mannose (D) Galactose a sucrose medium is

2. The polysaccharide found in the (A) Dextrans (B) Dextrin

exoskeleton of invertebrates is (C) Limit dextrin (D) Inulin

(A) Pectin (B) Chitin 7. Glucose on reduction with sodium

(C) Cellulose (D) Chondroitin sulphate amalgam forms
(A) Dulcitol (B) Sorbitol
3. Which of the following is a heteroglycan?
(C) Mannitol (D) Mannitol and sorbitol
(A) Dextrins (B) Agar
8. Glucose on oxidation does not give
(C) Inulin (D) Chitin
(A) Glycoside (B) Glucosaccharic acid
4. The glycosaminoglycan which does not
(C) Gluconic acid (D) Glucuronic acid
contain uronic acid is
9. Oxidation of galactose with conc HNO 3
(A) Dermatan sulphate
yields
(B) Chondroitin sulphate
(A) Mucic acid (B) Glucuronic acid
(C) Keratan sulphate
(C) Saccharic acid (D) Gluconic acid
(D) Heparan sulphate
10. A positive Benedict’s test is not given by
5. The glycosaminoglycan which does not
contain uronic acid is (A) Sucrose (B) Lactose
(C) Maltose (D) Glucose
(A) Hyaluronic acid
(B) Heparin
(C) Chondroitin sulphate
(D) Dermatan sulphate
 UNIT- III

1. The functions of plasma albumin are

6. An amino acid that does not form an -
(A) Osmosis (B) Transport helix is
(C) Immunity (D) both (A )and (B)
(A) Valine (B) Proline
2. Amino acid with side chain containing (C) Tyrosine (D) Tryptophan
basic groups is
7. An amino acid not found in proteins is
(A) 2-Amino 5-guanidovaleric acid
(A) -Alanine (B) Proline
(B) 2-Pyrrolidine carboxylic acid
(C) Lysine (D) Histidine
(C) 2-Amino 3-mercaptopropanoic acid
(D) 2-Amino propanoic acid 8. In mammalian tissues serine can be a
biosynthetic precursor of
3. An example of -amino acid not
(A) Methionine (B) Glycine
present in proteins but essential in
mammalian metabolism is (C) Tryptophan (D) Phenylalanine

(A) 3-Amino 3-hydroxypropanoic acid 9. A vasodilating compound is produced

(B) 2-Amino 3-hydroxybutanoic acid by the decarboxylation of the amino
acid:
(C) 2-Amino 4-mercaptobutanoic acid
(A) Arginine (B) Aspartic acid
(D) 2-Amino 3-mercaptopropanoic acid
(C) Glutamine (D) Histidine
4. An essential amino acid in man is
10. Biuret reaction is specific for
(A) Aspartate (B) Tyrosine
(A) –CONH-linkages (B) –CSNH2 group
(C) Methionine (D) Serine
(C) –(NH)NH2 group (D) All of these
5. Non essential amino acids
(A) Are not components of tissue proteins
(B) May be synthesized in the body from
essential amino acids
(C) Have no role in the metabolism
(D) May be synthesized in the body in diseased
states
 UNIT- IV

1. A nucleoside consists of 7. The chemical name of guanine is

(A) Nitrogenous base (A) 2,4-Dioxy-5-methylpyrimidine
(B) Purine or pyrimidine base + sugar (B) 2-Amino-6-oxypurine
(C) Purine or pyrimidine base + phosphorous (C) 2-Oxy-4-aminopyrimidine
(D) Purine + pyrimidine base + sugar + (D) 2, 4-Dioxypyrimidine
phosphorous
8. Nucleotides and nucleic acids
2. A nucleotide consists of
concentration are often also expressed
(A) A nitrogenous base like choline in terms of
(B) Purine + pyrimidine base + sugar + (A) ng (B) mg
phosphorous
(C) meq (D) OD at 260 nm
(C) Purine or pyrimidine base + sugar
(D) Purine or pyrimidine base + phosphorous 9. The pyrimidine nucleotide acting as the
high energy intermediate is
3. A purine nucleotide is
(A) ATP (B) UTP
(A) AMP (B) UMP
(C) UDPG (D) CMP
(C) CMP (D) TMP
10. The carbon of the pentose in ester
4. A pyrimidine nucleotide is
linkage with the phosphate in a
(A) GMP (B) AMP nucleotide struc- ture is
(C) CMP (D) IMP
(A) C1 (B) C3
5. Adenine is (C) C4 (D) C5
(A) 6-Amino purine
11. Uracil and ribose form
(B) 2-Amino-6-oxypurine
(C) 2-Oxy-4-aminopyrimidine (A) Uridine (B) Cytidine
(D) 2, 4-Dioxypyrimidine (C) Guanosine (D) Adenosine

6. 2, 4-Dioxypyrimidine is 12. The most abundant free nucleotide in

mammalian cells is
(A) Thymine (B) Cystosine
(C) Uracil (D) Guanine (A) ATP (B) NAD
(C) GTP (D) FAD
 UNIT- V

1. The total body water in various 7. The fluid present in bones which can
subjects is relatively constant when not be exchanged readily because of
expressed as percentage of the lean relative avascularity is about
body mass and is about
(A) 20 ml/kg (B) 25 ml/kg
(A). 30% (B) 40%
(C) 45 ml/kg (D) 60 ml/kg
(C) 50% (D) 70%
2.. The percentage of water contained in the 8. Water derived in gm from complete
body of an individual is less because of oxidation of each gm of carbohydrate is
about
(A) High fat content (B) Low fat content
(C) High protein content(D) Low protein content (A) 0.15 (B) 0.25
(C) 0.35 (D) 0.55
3. In intracellular compartment the fluid
present in ml/kg body weight is about 9. The oxidation of 100 gm of fat yields
(A) 100 (B) 200 (A) 50 gm water (B) 107 gm water
(C) 200 (D) 330 (C) 150 gm water (D) 200 gm water
4. In extra cellular compartment, the fluid
10. Each gm of protein on complete
present in ml/kg of body weight is
about oxidation yields

(A) 120 (B) 220 (A) 0.21 gm water (B) 0.31 gm water
(C) 270 (D) 330 (C) 0.41 gm water (D) 0.51 gm water

5. Fluid present in dense connective 11. The daily total body water derived from
tissue and cartilage in ml/kg body oxidation of food stuffs is about
weight is about
(A) 100 ml (B) 300 ml
(A) 10 (B) 20
(C) 600 ml (D) 1000 ml
(C) 45 (D) 55
12. The daily water allowance for normal
6. The total body water in ml/kg body
infant is about
weight in average normal young adult
male is about (A) 100–200 ml (B) 250–300 ml
(A) 200 (B) 400 (C) 330–1000 ml (D) 1000–2000 ml
(C) 600 (D) 1000