Inheritance j23
Inheritance j23
Inheritance J23
C.V
                                                                                 r
                                                                         ab
   Independent
        Temp
        Humidity                                               G
                                        al
                               ih
                           N
                                                                                                                   Variation
                      r.
                 D
Effect of temperature
Effect of humidity
                                                      648
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Skills
                                                                    r
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                                                         G
                                  al
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                                                                                                     Inheritance
                     N
                r.
          D
                                                649
     Dr.Nihal Gabr   Downloaded by Mariam I (bingbong662chnag@gmail.com)
                                                 lOMoARcPSD|42126020
4-
                                                                               br
                                                                       Ga
Direct
                               l
                           iha
                                                                                                                   Inheritance
                        .N
               Dr
                         BB
                         XX
                                                                             br
                                                                                                              Inheritance
Skills
                                l                                           Ga
                            iha
                         .N
               Dr
                                                                                    br
                                                                                                              Inheritance
                            l                                         Ga
                        iha
                     .N
               Dr
Thinking
                                                                   br
                                  l                               Ga
                               ha
               .     Ni
            Dr
Direct
                                                                                                                 Inheritance
         ⑪                                                                                       -
                                                                         r
     18
                                                                       ab
               Page 8         October/november2011                     Syllabus-0610          Paper 32
                                       lG
                         iha
              .N
            Dr
Direct
                                                                r
                                                              ab
                              lG
                                                                                                Variation
                iha
     .N
   Dr
                                      me
                                                                 D
                                                                r
                                                              ab
                                                                                                Variation
                              lG
                iha
     .N
   Dr
13
(iii) The doctors concluded that some diets reduce the risk of CHD.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
[Total: 23]
                 ...........................................................................................................................................
Direct                                not taken yet
                 ...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
                 ...........................................................................................................................................
Direct           ...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
14
    (b) Ecologists in one country were concerned that some mammals had been affected by
        deforestation.
Fig. 4.1 is a diagram showing how deforestation affected one area of forest.
                  Key:
                         forest
                         cleared land
original forest
remaining forest
Fig. 4.1
         The ecologists studied eight species of mammal. They recorded how many of the small and
         large areas of the remaining forest contained each of the eight species.
         Two species, the black rat and the house mouse, are not usually found in this forest
         ecosystem. They were introduced to the area by humans many years ago before any trees
         were cut down.
The other six species are known to live in this forest ecosystem.
15
Table 4.1
                                                                                                  ⑧                                              9
   long-nosed potoroo                                     1100                                     8                                     17     =
..................................................................................................................................... [1]
 ranite
                    Discuss the evidence from Table 4.1 to support or reject this hypothesis.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
                    ...........................................................................................................................................
Skills              ...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [4]
[Total: 11]
2-
                                                                                                                        Inheritance
                                                                              r
                                                                            ab
                                            lG
                             iha
          .N
1-
Inheritance
                                                                r
                                                              ab
                              lG
                                                                  ⑧
                iha
                                                              &
                                                              -
     .N
                                                       -
   Dr
IIIII
                                                              it
          1                                  IIIIII
                                                                r
                                                              ab
                                                                                                 Variation
                              lG
                iha
     .N
                                                                                                Skills
   Dr
                                                                                                                              Variation
Direct
                                                                                      r
                                                                                    ab
         W
         24      Effect of mutation
                                                    lG
                                         October/november2012                       Syllabus-0610        Paper 33
                                      iha
                  .N
                Dr
Inheritance
                                                                 r
                                                               ab
                                                                                                         Linked to biotechnology( genetic engineering)
                               lG
                 iha
       .N
     Dr
Direct
                                                                         r
                                                                       ab
                                       lG
                         iha
              .N
            Dr
① Variation
                                                                                                                     Variation
①Due to mutation where there is a change in gene                          reulting in new alleles .
①Changes in environmental conditions acts as a Selection pressure
①Those have favorable characteristic are able to survive being better adapted
①While those with less fav. Ch. die
                                                                            r
①Survival of fittest, where the better adapted will be able to reproduce and pass on
                                                                          ab
①the favourable allele to the coming genertaions
①Increasing the frequency of allele coding for adaptive feature in the population
24     Effect of mutation
                                          lG
                               October/november2012                       Syllabus-0610           Paper 33
                            iha
       .N
     Dr
Inheritance
Direct
                                                 br
                                           l Ga
                                               ba r
                                       ihal G
                                                                                                         Inheritance
X
                         iNha
 X
            Dr .N
&
  I
              .
            Dr
Skills
                                                                         r
                                                                       ab
                                       lG
  Direct
                         iha
Direct
                                                                               r
                                                                             ab
                                     6
                                             lG
                               iha
             .N
           Dr
Skills
Direct
                                                                     r
                                                                   ab
                                   lG
                     iha
           .N
         Dr
Direct           ⑪
                 ①
                                                                     r
                                                                   ab
                                   lG
                     iha
          .N
        Dr
Direct
              ①
  Direct     ①
              ①
              ⑪
              ⑪
                                                                           r
             ⑪
                                                                         ab
                                         lG
                           iha
                .N
              Dr
Direct
                                                                              r
                                                                            ab
                                      lG
                     iha
          .N
        Dr
Ligase -
                                      gene
                                              .
                        Recombinant
                               DNA                .
Restri
Direct
                                                                         r
                                                                       ab
                                       lG
                         iha
              .N
Direct
            Dr
Skills
                                                                           r
                                                                         ab
                                         lG
Crops that are resistant to herbicide .....( soya bean )...kill weeds only thus
                          iha
increasing crop yield and quality by decreasing competition on minerals, water
and light .
           .N
Crops that produce their own toxins....( cotton plants) ..less use of insecticides ,
         Dr
avoid killing useful insects , less pollution , increase in crop yield and quality, less
money spent on insecticides , less chance for insects to become resistance .
Crops that are reach in nutrients such as golden rice rich in vitamin A
Increase nutritional value
                                                                       r
                                                                     ab
                                     lG
                       iha
             .N
     Direct
           Dr
Direct
                                                                         r
                                                                       ab
                                       lG
Linked to
   plant
                         iha
 tropism
              .N
Direct
            Dr
                                                                         r
Skills
                                                                       ab
                                       lG
                         iha
              .N
            Dr
                                                                         r
                                                                       ab
                                      lG
                       iha
             .N
           Dr
                                                                r
                                                              ab
                              lG
                iha
     .N
   Dr
18
                                                                                                                      Key:
                                                          base pair
                                                                                                                                    base A
Fig. 6.1
(a) (i) State the letter of the base that pairs with A.
..................................................................................................................................... [1]
..................................................................................................................................... [1]
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [2]
19
(c) Fig. 6.2 shows a plant tissue in which cells are dividing by mitosis.
                   J
                                                                                                                              H
Fig. 6.2
                State what happens to the chromosomes in cell H before mitosis takes place and state
                why it is necessary.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
                State the structures that will form between the nuclei so that the cell divides into two
                cells.
...........................................................................................................................................
..................................................................................................................................... [2]
20
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [1]
[Total: 9]
Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every
reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the
publisher will be pleased to make amends at the earliest possible opportunity.
To avoid the issue of disclosure of answer-related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge
Assessment International Education Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download
at www.cambridgeinternational.org after the live examination series.
Cambridge Assessment International Education is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of the University of
Cambridge Local Examinations Syndicate (UCLES), which itself is a department of the University of Cambridge.
18
6   Colour blindness is a characteristic that is inherited. Colour blindness is more common in males
    than in females.
Fig. 6.1 is a pedigree diagram showing the inheritance of colour blindness in a family.
                                                                                                    Key:
                                                                                                            male with normal
                                                                                                            colour vision
                                                                                                            male with colour
                                                                                                            blindness
                                       1                      2
                                                                                                            female with normal
                                                                                                            colour vision
                                                  3                       4
5 6 7 8
Fig. 6.1
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [1]
    (b) (i)      Using the symbols B and b, state the genotypes of individual 5 and individual 8 in the
                 pedigree diagram.
5 ........................................................................................................................................
                 8 ........................................................................................................................................
                                                                                                                                                       [3]
19
         (ii)   Individual 3 is a carrier of colour blindness because she has one copy of the allele for
                   /
Describe the evidence from Fig. 6.1 that shows that individual 3 is a carrier.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
        (iii)   There was no history of colour blindness in the parents and grandparents of individuals 1
                and 2.
Suggest how colour blindness first occurred in the family in Fig. 6.1.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
[Total: 9]
3   The American writer Ernest Hemingway lived on the island of Key West in Florida, USA in the
    1930s. During this time he was given a male cat by a sea captain.
    The cat had more toes than usual. This inherited condition is called polydactyly. The allele for
    polydactyly is dominant.
...................................................................................................................................................
............................................................................................................................................. [1]
                                                                                                 -t
                                                             1                                   2
3 4 5 6 7 8 9 10
11 12 13 14 15 16
     Key:
                                                                                                           17
                female cat with normal                             female cat with
                number of toes                                     polydactyly
Fig. 3.1
(i) State the genotypes of cats 5, 6 and 14 in the pedigree diagram in Fig. 3.1.
cat 5 ..................................................................................................................................
cat 6 ..................................................................................................................................
                cat 14 ................................................................................................................................
                                                                                                                                                   [3]
(ii) Explain why none of the offspring of cats 3 and 4 have inherited polydactyly.
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [1]
10
    (c) Scientists published the results of an investigation into the DNA of cats with and without
        polydactyly. They compared the base sequence from a particular region of DNA that controls
        the development of the limbs.
          (i)   Describe how the base sequences of the cats with polydactyly differ from the base
                sequence of cats without polydactyly.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
(ii) State the name of the process by which base sequences in DNA are changed.
..................................................................................................................................... [1]
        (iii)   The base sequences in Table 3.1 provide evidence that indicates which country the male
                cat given to Hemingway in the 1930s came from.
Suggest which country this cat came from and give a reason for your choice.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
11
(d) Fig. 3.2 shows part of a DNA molecule from a chromosome of a cat.
         Complete Fig. 3.2 by writing the letters for the base sequence of the other strand of the DNA
         molecule.
T ..........
A ..........
A ..........
T ..........
G ..........
C ..........
G ..........
T ..........
G ..........
                                                                     Fig. 3.2
                                                                                                                                                         [1]
...................................................................................................................................................
...................................................................................................................................................
                                                                                                                           ⑪
          ...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [2]
[Total: 13]
11
3   Cheetahs, Acinonyx jubatus, are carnivores found in the dry grasslands and woodlands of
    southern Africa. Cheetahs hunt for food during the day. They eat deer and antelope.
    The cheetah is the fastest mammal on land but can only run at high speed (sprint) over a short
    distance. Its hunting strategy is to creep up on prey and then sprint to catch them.
Fig. 3.1
(a) Suggest how these adaptive features enable cheetahs to survive in their natural environment.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
          ...................................................................................................................................................
                                                                                                                                                         [2]
12
(b) The king cheetah is a rare variety of A. jubatus that has inherited striped fur markings.
Fig. 3.2
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [1]
13
1 2
3 4 5 6 7 8 9 10
BD BD
  11            12              13               14                                                15       16       17            18               19
  bob                                              ?
Key:
Fig. 3.3
..................................................................................................................................... [1]
..................................................................................................................................... [1]
(iv) Describe how a breeder could determine the genotype of cheetah 17.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
14
(v) When the king cheetah was first discovered it was thought that it was a new species.
                Suggest one type of evidence, other than pedigree diagrams, that can be used to
                determine how closely related organisms are.
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [1]
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
[Total: 14]
18
5 The Galápagos Islands are a group of small islands in the Pacific Ocean.
    In 1839 Charles Darwin published a book that described differences in a family of birds called
    finches.
         •       a different diet
         •       a different beak shape, as shown in Fig. 5.1.
Fig. 5.1
    (a) State the genus name for the Galápagos finches shown in Fig. 5.1.
                                Geospiza
          ............................................................................................................................................. [1]
19
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [5]
[Total: 6]
1. Variation
2. Due to mutation ( definition)...producing new allele
3. Selection pressure ( mention)
4. Those who have favorable characteristic ( mention) ...are able to survive
5. Those with less favorable characteristics ( mention) less chance to
survive / die
6. Survival of fittest ...so they breed and pass on the advantageous allele to
the coming generation
7. Increasing the frequency of allele in the population .
8. By natural selection
Recommended 5
Fig. 2.1
Fig. 2.2 shows a red panda, Ailurus fulgens, and a polar bear, Ursus maritimus.
(a) State one dietary component that is more likely to be found in bamboo plants than in fish.
............................................................................................................................................. [1]
    (b) (i)      State two features, visible in Fig. 2.1 and Fig. 2.2, that identify the three animals as all
                 belonging to the same vertebrate group.
1 ........................................................................................................................................
                 2 ........................................................................................................................................
                                                                                                                                                       [2]
                Molecular biologists compared the DNA base sequences of eight species from the same
                vertebrate group. They used the differences to draw a classification diagram.
                Fig. 2.3 shows the classification diagram for these eight species. The shorter the
                horizontal distance from two species to the branching point that they share, the more
                similar their DNA sequences are and the more closely the two species are related.
                The scale on Fig. 2.3 shows the time at which the molecular biologists estimate that
                each branching point occurred.
red panda
                                                                                                    :
                                                                                           ferret
giant panda
polar bear
wolf
tiger
human
mouse
100                 80                60               40                      20      0
                                       million years ago
Fig. 2.3
                           External features                                7
                           *
                Morphology can also be used to classify species. Some scientists think that morphology
                suggests that the giant panda is more closely related to the red panda than it is to the
                polar bear.
                Discuss the evidence for and against the giant panda being more closely related to
                the red panda than it is to the polar bear. Use the information in Fig. 2.1, Fig. 2.2 and
                Fig. 2.3 in your answer.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [5]
(iii) State one other type of evidence that is used to classify species.
..................................................................................................................................... [1]
[Total: 9]
    Recommended                                                                                     www.dynamicpapers.com
                                                                         10
    The bodies of fruit flies can be black or yellow. A yellow body colour is a recessive feature in fruit
    flies.
(a) Two heterozygous fruit flies with black bodies were bred together.
Predict the phenotypes of the offspring and the phenotypic ratio for this cross.
............................................................................................................................................. [1]
    (b) In another fruit fly breeding experiment, researchers counted 124 offspring with black bodies
        and 121 offspring with yellow bodies.
         Draw a genetic diagram to explain the results of this cross. Use the letter B to represent the
         allele for black body colour and the letter b to represent the allele for yellow body colour.
         gametes                                                   ,                                ×                          ,
                                                 .............             .............                     .............           .............
                                                                                              www.dynamicpapers.com
                                                                       11
(c) The crab, Cerberusa caeca, lives in dark caves and has no coloured pigment.
Fig. 3.1
State one feature present in all arthropods but not present in vertebrates.
..................................................................................................................................... [1]
..................................................................................................................................... [1]
                                                                                               www.dynamicpapers.com
                                                                        12
         The lack of a coloured pigment in C. caeca is called albinism and was caused by a mutation
         many thousands of years ago.
          (i)   Explain the mechanism that has resulted in the allele for albinism becoming common in
                recent generations in populations of C. caeca.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
1 ........................................................................................................................................
                2 ........................................................................................................................................
                                                                                                                                                      [2]
[Total: 13]
2 (a) Two tomato plants that produce red fruit were bred together.
This cross produced 71 offspring plants with red fruit and 26 offspring plants with yellow fruit.
         Select a suitable letter to represent the alleles and decide which allele will need a capital
         letter and which allele will need a lower case letter.
         gametes                                                    ,                                            ×                        ,
                                                  .............                .............                          .............             .............
    (b) Researchers carried out some experiments on tomato plants that were homozygous for fruit
        colour.
State how the researchers could be sure that the fruit came from homozygous plants.
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [1]
                                                                                                   www.dynamicpapers.com
                                                                                7
     (c) The researchers analysed two pigments, chlorophyll and lycopene, in homozygous red
         tomato fruit and homozygous yellow tomato fruit. Chlorophyll is found in unripe tomato fruit.
                   ...........................................................................................................................................
Direct
                   ...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
(ii) State the name of one mineral required for the synthesis of chlorophyll.
..................................................................................................................................... [1]
         (iii)     The researchers analysed the concentration of the pigments in tomato fruits:
                   •   before they were ready to eat (unripe)
                   •   when they were ready to eat (ripe).
Table 2.1
                   Use the information in Table 2.1 to compare the changes in pigments in red fruit and
                   yellow fruit as they ripen.
...........................................................................................................................................
                   ...........................................................................................................................................
Skills
                   ...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [3]
                                                                                               www.dynamicpapers.com
                                                                            8
    (d) A gene is responsible for the production of lycopene in fruits. Geneticists have recently
        produced genetically modified pink pineapples using the gene associated with the production
        of lycopene.
                                          DNA
                ..................................................................................................................................... [1]
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
[Total: 16]
    Recommended                                                                                  www.dynamicpapers.com
                                                                            6
Fig. 2.1 shows the procedure for crossing two plants of the same species.
                                                                                              pollen transferred
                                           stigma ready to                                    to the stigma of
                                           receive pollen                                     flower 1
                                                                                                    bag placed
                                                                                                    around flower 1
                                                                                                    and tied tightly
Fig. 2.1
         The scientist collected the seeds and germinated them. The leaves and flowers of the offspring
         plants showed phenotypic variation as they were not all identical to the parent plants.
         The scientist then investigated the chromosomes of all the offspring plants and found that
         they had exactly the same number of chromosomes as the parent plants.
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
                                                                                                    www.dynamicpapers.com
                                                                                 7
                                  Prevent pollination
                     ...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [1]
             (iii)   Explain how sexual reproduction results in the variation that the scientist discovered in
Direct               the offspring plants.
                                    -
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
             (iv)    The chromosome number of the offspring plants is the same as the chromosome number
                     of the parent plants in this investigation.
Explain how the chromosome number is maintained from one generation to the next.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
                                                                                     www.dynamicpapers.com
                                                            8
                                                                              Co dominance
    (b) The plant Camellia japonica has flowers that can be white, red or a mixture of these two
        colours. When red-flowered plants are crossed with white-flowered plants, all the offspring
        plants have flowers with petals that are a mixture of red and white, as shown in Fig. 2.2.
June 2016
Fig. 2.2
                Complete Table 2.1 by giving all the possible genotypes of the offspring plants that could
                be produced by these parent plants.
                                                                                                     www.dynamicpapers.com
                                                                            9
Table 2.1
 petals that are both red                petals that are both red
 and white                               and white
[3]
(ii) State the type of inheritance that is shown by petal colour in C. japonica.
..................................................................................................................................... [1]
[Total: 11]
                                                                                                 www.dynamicpapers.com
                                                                          16
Fig. 6.1
    (a) Describe the negative impacts to an ecosystem of large-scale monocultures, such as the one
        shown in Fig. 6.1.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
............................................................................................................................................. [3]
                                                                                                     www.dynamicpapers.com
                                                                        17
(b) The fruits of maize are produced on structures called cobs. Each cob has many fruits.
         Fig. 6.2 shows how the maize cobs have changed over thousands of years as a result of
         selective breeding.
fruit
     length of
     maize cob                                                                                                                    maize cob
time
Fig. 6.2
         State two desirable features, visible in Fig. 6.2, that have been selected from the more
         ancient varieties of maize.
1 ................................................................................................................................................
         2 ................................................................................................................................................
                                                                                                                                                       [2]
                                                                                               www.dynamicpapers.com
                                                                        18
(c) The process of selective breeding involves a series of steps, as shown in Fig. 6.3.
Fig. 6.3
(i) Explain why the flowers are covered with bags in step 3.
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [1]
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
                ..................................................................................................................................... [2]
© UCLES 2021                                                    0610/41/O/N/21
                                                                                               www.dynamicpapers.com
                                                                        19
        (iii)   Explain why some of the plants in step 5 may show features not visible in the parent
                plants.
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [1]
(iv) Suggest why selective breeding should continue for many generations (step 6).
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [2]
         (v)    State how new features, which did not exist in ancient varieties of a crop plant, could
                appear.
...........................................................................................................................................
...........................................................................................................................................
..................................................................................................................................... [1]
[Total: 12]
         (e) If CFTR proteins do not move chloride ions, the liquid in the pancreatic duct becomes very
             sticky and the duct can become blocked.
             Blocked pancreatic ducts are one effect of cystic fibrosis, which is an inherited disease. Cystic
             fibrosis is caused by a mutation of the gene that codes for the CFTR protein.
Fig. 3.3 shows the pedigree diagram of a family that has two people who have cystic fibrosis.
1 2 3
                                                     4                       5                     6                 7
                                  Key:
Fig. 3.3
                    Describe and explain the evidence shown in Fig. 3.3 that cystic fibrosis is caused by a
Skills              recessive allele.
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13
(ii) Person 7 is expecting a child with a man who is heterozygous for cystic fibrosis.
                 Complete the genetic diagram to predict the probability of person 7 and the heterozygous
                 man having a child with cystic fibrosis.
Use the symbol A for the dominant allele and a for the recessive allele.
                 parental genotypes                          aa
                                                          ................                                    ................
gametes +
Direct
[Total: 21]