Cfas Lipid
Cfas Lipid
1.2 Relevant identified uses of the substance or mixture and uses advised against
     Recommended restrictions      : For professional users only.
     on use
    Telephone                             : +496217590
    Telefax                               : +496217592890
    Responsible Department                : +49(0)621-759-4223
    E-mail address                        : info.dia-sds@roche.com
1.4 Emergency telephone number
     In case of emergencies:  :             Central Works Security         +49(0)621-759-2203
                                            Roche Diagnostics GmbH
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                     Revision Date:                 Date of last issue: 21.08.2021
1.12                        17.02.2022                     Date of first issue: 30.03.2015
disposal plant.
    Ecological information: The substance/mixture does not contain components considered to have
    endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regu-
    lation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
3.2 Mixtures
     Chemical nature               :    Handle as potentially infectious.
    Components
    Chemical name                        CAS-No.                  Classification             Concentration
                                         EC-No.                                                (% w/w)
                                         Index-No.
                                         Registration number
    sodium azide                         26628-22-8               Acute Tox. 2; H300         >= 0,25 - < 1,0
                                         247-852-1                Acute Tox. 2; H330
                                         011-004-00-7             Acute Tox. 1; H310
                                         01-2119457019-37         STOT RE 2; H373
                                                                  Aquatic Acute 1;
                                                                  H400
                                                                  Aquatic Chronic 1;
                                                                  H410
                                                                  EUH032
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                       Revision Date:                 Date of last issue: 21.08.2021
1.12                          17.02.2022                     Date of first issue: 30.03.2015
4.2 Most important symptoms and effects, both acute and delayed
     None known.
4.3 Indication of any immediate medical attention and special treatment needed
     Treatment                   : The first aid procedure should be established in consultation
                                    with the doctor responsible for industrial medicine.
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                      Revision Date:                 Date of last issue: 21.08.2021
1.12                         17.02.2022                     Date of first issue: 30.03.2015
    Advice on protection against    :    Provide appropriate exhaust ventilation at places where dust
    fire and explosion                   is formed.
    Hygiene measures                :    Handle in accordance with good industrial hygiene and safety
                                         practice.
                                                  4 / 15
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                      Revision Date:                Date of last issue: 21.08.2021
1.12                         17.02.2022                    Date of first issue: 30.03.2015
    Engineering measures
    No data available
    Personal protective equipment
    Eye protection             : Safety glasses
    Hand protection
      Material                     :   Protective gloves
                                                5 / 15
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                          Revision Date:                  Date of last issue: 21.08.2021
1.12                             17.02.2022                      Date of first issue: 30.03.2015
Colour : white
light yellow
Odour : none
pH : Not applicable
    Viscosity
       Viscosity, dynamic                :   Not applicable
    Solubility(ies)
       Water solubility                  :   soluble
                                                       6 / 15
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                         Revision Date:                    Date of last issue: 21.08.2021
1.12                            17.02.2022                        Date of first issue: 30.03.2015
10.1 Reactivity
     No dangerous reaction known under conditions of normal use.
10.2 Chemical stability
     Stable under normal conditions.
10.3 Possibility of hazardous reactions
     Hazardous reactions           : No dangerous reaction known under conditions of normal use.
    Acute toxicity
    Not classified based on available information.
    Product:
    Acute oral toxicity               :       Acute toxicity estimate: > 2.000 mg/kg
                                              Method: Calculation method
Components:
    sodium azide:
    Acute oral toxicity               :       LD50 Oral (Rat): 27 mg/kg
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                         Revision Date:                Date of last issue: 21.08.2021
1.12                            17.02.2022                    Date of first issue: 30.03.2015
    Skin corrosion/irritation
    Not classified based on available information.
    Components:
    sodium azide:
    Method                            :   OECD Test Guideline 439
    Result                            :   No skin irritation
    sodium azide:
    Species                           :   Bovine cornea
    Exposure time                     :   4h
    Method                            :   OECD Test Guideline 437
    Result                            :   No eye irritation
    Skin sensitisation
    Not classified based on available information.
    Respiratory sensitisation
    Not classified based on available information.
    Components:
    sodium azide:
    Test Type                         :   Local lymph node assay (LLNA)
    Species                           :   Mouse
    Method                            :   OECD Test Guideline 429
    Result                            :   negative
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                     Revision Date:               Date of last issue: 21.08.2021
1.12                        17.02.2022                   Date of first issue: 30.03.2015
    sodium azide:
    Genotoxicity in vitro          :   Test Type: Chromosome aberration test in vitro
                                       Test system: Chinese hamster ovary cells
                                       Result: negative
    Carcinogenicity
    Not classified based on available information.
    Reproductive toxicity
    Not classified based on available information.
    STOT - single exposure
    Not classified based on available information.
    STOT - repeated exposure
    Not classified based on available information.
    Components:
    sodium azide:
    Assessment                     :   May cause damage to organs through prolonged or repeated
                                       exposure.
Components:
    sodium azide:
    Species                        :   Rat
    NOAEL                          :   5 mg/kg
    LOAEL                          :   10 mg/kg
    Application Route              :   Oral
    Exposure time                  :   24 Months
    Method                         :   OECD Test Guideline 453
    Species                        :   Rat
    NOAEL                          :   10 mg/kg
    LOAEL                          :   20 mg/kg
    Application Route              :   Oral
    Exposure time                  :   90 d
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                        Revision Date:                Date of last issue: 21.08.2021
1.12                           17.02.2022                    Date of first issue: 30.03.2015
    Aspiration toxicity
    Not classified based on available information.
11.2 Information on other hazards
    Product:
    Assessment                       :   The substance/mixture does not contain components consid-
                                         ered to have endocrine disrupting properties according to
                                         REACH Article 57(f) or Commission Delegated regulation
                                         (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at
                                         levels of 0.1% or higher.
12.1 Toxicity
Components:
    sodium azide:
    Toxicity to fish                 :   LC50 (Pimephales promelas (fathead minnow)): 5,46 mg/l
                                         Exposure time: 96 h
                                         Test Type: flow-through test
                                         Method: OECD Test Guideline 203
    Toxicity to daphnia and other :      EC50 (Daphnia magna (Water flea)): 0,4 mg/l
    aquatic invertebrates                Exposure time: 48 h
    Ecotoxicology Assessment
    Acute aquatic toxicity   :           Very toxic to aquatic life.
Chronic aquatic toxicity : Very toxic to aquatic life with long lasting effects.
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                         Revision Date:               Date of last issue: 21.08.2021
1.12                            17.02.2022                   Date of first issue: 30.03.2015
Components:
    sodium azide:
    Biodegradability                  :   Remarks: The methods for determining biodegradability are
                                          not applicable to inorganic substances.
Components:
    sodium azide:
    Partition coefficient: n-         :   Remarks: Not applicable
    octanol/water
    Product:
    Assessment                        :   This substance/mixture contains no components considered
                                          to be either persistent, bioaccumulative and toxic (PBT), or
                                          very persistent and very bioaccumulative (vPvB) at levels of
                                          0.1% or higher.
    Product:
    Assessment                        :   The substance/mixture does not contain components consid-
                                          ered to have endocrine disrupting properties according to
                                          REACH Article 57(f) or Commission Delegated regulation
                                          (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at
                                          levels of 0.1% or higher.
    Product:
    Additional ecological infor-      :   An environmental hazard cannot be excluded in the event of
    mation                                unprofessional handling or disposal.
                                          Harmful to aquatic life with long lasting effects.
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                    Revision Date:                  Date of last issue: 21.08.2021
1.12                       17.02.2022                      Date of first issue: 30.03.2015
local regulations.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mix-
ture
     REACH - Restrictions on the manufacture, placing on    : Not applicable
     the market and use of certain dangerous substances,
     mixtures and articles (Annex XVII)
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                      Revision Date:              Date of last issue: 21.08.2021
1.12                         17.02.2022                  Date of first issue: 30.03.2015
    Other regulations:
    Take note of Law on the protection of mothers at work, in education and in studies (Maternity
    Protection Act - MuSchG).
    DSL                            :   This product contains the following components that are not
                                       on the Canadian DSL nor NDSL.
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                     Revision Date:               Date of last issue: 21.08.2021
1.12                        17.02.2022                   Date of first issue: 30.03.2015
    ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland
    Waterways; ADR - Agreement concerning the International Carriage of Dangerous Goods by
    Road; AIIC - Australian Inventory of Industrial Chemicals; ASTM - American Society for the Test-
    ing of Materials; bw - Body weight; CLP - Classification Labelling Packaging Regulation; Regula-
    tion (EC) No 1272/2008; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard
    of the German Institute for Standardisation; DSL - Domestic Substances List (Canada); ECHA -
    European Chemicals Agency; EC-Number - European Community number; ECx - Concentration
    associated with x% response; ELx - Loading rate associated with x% response; EmS - Emergen-
    cy Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration as-
    sociated with x% growth rate response; GHS - Globally Harmonized System; GLP - Good La-
    boratory Practice; IARC - International Agency for Research on Cancer; IATA - International Air
    Transport Association; IBC - International Code for the Construction and Equipment of Ships car-
    rying Dangerous Chemicals in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - Interna-
    tional Civil Aviation Organization; IECSC - Inventory of Existing Chemical Substances in China;
    IMDG - International Maritime Dangerous Goods; IMO - International Maritime Organization; ISHL
    - Industrial Safety and Health Law (Japan); ISO - International Organisation for Standardization;
    KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a test popula-
    tion; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose); MARPOL - Interna-
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SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
C.f.a.s. Lipids
Version                     Revision Date:               Date of last issue: 21.08.2021
1.12                        17.02.2022                   Date of first issue: 30.03.2015
    tional Convention for the Prevention of Pollution from Ships; n.o.s. - Not Otherwise Specified;
    NO(A)EC - No Observed (Adverse) Effect Concentration; NO(A)EL - No Observed (Adverse) Ef-
    fect Level; NOELR - No Observable Effect Loading Rate; NZIoC - New Zealand Inventory of
    Chemicals; OECD - Organization for Economic Co-operation and Development; OPPTS - Office
    of Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic sub-
    stance; PICCS - Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quanti-
    tative) Structure Activity Relationship; REACH - Regulation (EC) No 1907/2006 of the European
    Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Re-
    striction of Chemicals; RID - Regulations concerning the International Carriage of Dangerous
    Goods by Rail; SADT - Self-Accelerating Decomposition Temperature; SDS - Safety Data Sheet;
    SVHC - Substance of Very High Concern; TCSI - Taiwan Chemical Substance Inventory; TECI -
    Thailand Existing Chemicals Inventory; TRGS - Technical Rule for Hazardous Substances; TSCA
    - Toxic Substances Control Act (United States); UN - United Nations; vPvB - Very Persistent and
    Very Bioaccumulative
    Further information
    Classification of the mixture:                              Classification procedure:
    Aquatic Chronic 3             H412                          Calculation method
    The information provided in this Safety Data Sheet is correct to the best of our knowledge, infor-
    mation and belief at the date of its publication. The information given is designed only as a guid-
    ance for safe handling, use, processing, storage, transportation, disposal and release and is not
    to be considered a warranty or quality specification. The information relates only to the specific
    material designated and may not be valid for such material used in combination with any other
    materials or in any process, unless specified in the text.
DE / EN / 2104
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