DRUG STUDY

Prescribed and
BRAND NAME Recommended Mechanism
Nursing
GENERIC NAME dosage, frequency, Of Indication Contraindication Adverse Reaction
Responsibilities
CLASSIFICATION route of Action
administration
Generic name: Usual Adult Dose for You should not use •Have phentolamine IV
Depression: phenelzine if you are ready for
Phenelzine The basic mechanism Phenelzine is indicated allergic to it, or if you • sudden and severe hypertensive crisis
of action of phenelzine for the treatment of have: headache, neck
Early phase treatment:
acts as an inhibitor and nonendogenous, pain , or stiffness.
-Initial dose: 15 mg substrate of • pounding •Inform client it can
Brand name: neurotic, or atypical • pheochromocyt
orally monoamine oxidase heartbeats or take 1-3 weeks to
depression for patients oma being feeling
Nardil which subsequently fluttering in your
3 times a day that do not tolerate (tumor of the effects and 2-3
causes an elevation in chest.
other forms of therapy. adrenal gland). months full effects
brain levels of • fast or slow
-Dose titration: • congestive
Classification: catecholamines and heartbeats.
Increase to at least 60 heart failure.
serotonin. It also • chest pain. •Stay alert to changes
mg per day • severe kidney
Antidepressants, MAO presents a similar • a light-headed in mood or
fairly rapidly, as structure to disease; or
feeling, like you symptoms. Report
Inhibitors • a history of
tolerated might pass out. • any new or
amphetamine which liver problems
sweating worsening
-Maximum dose: 90 explains the effect on or abnormal
(sometimes with symptoms to your
mg/day the uptake and release liver function doctor.
fever and
of dopamine, tests.
sometimes with
noradrenaline, and cold, clammy skin); •Avoid tyramine-
Maintenance:
serotonin. Phenelzine • nausea, vomiting; containing
-Maintenance dose has been reported to or foods/beverages
may be as low as 15 inhibit tyrosine dilated pupils (your during therapy (like
mg orally once a day or aminotransferase, eyes may be more cheese, smoked
15 mg orally every aromatic amino acid sensitive to light). meats, avocados,
other day decarboxylase, and bananas, and soy
-Duration of therapy:
dopamine sauce) and for 2
As long as required
Bhydroxylase. weeks after
discontinuing
phenelzine.

• Avoid any
spoiled or
improperly
refrigerated,
handled, or stored
protein-rich foods
(eg, meat, fish, and
dairy products
[including foods
that have
undergone smoking
to improve flavor]).