UNIVERSITY OF NEGROS OCCIDENTAL-RECOLETOS
College of Allied Medical Health Sciences
Medical Technology Program
TOPIC OUTLINE
SEROLOGY AND IMMUNOLOGY LECTURE
1ST Semester 2024-2025
Course Description: SEROIM54P is a four-unit lecture and laboratory course that
deals with the basic concepts of Immunology and the principles and
procedures of serological tests and subsequently reading,
interpreting, and proper reporting of results. It seeks to provide students
immunologic and serologic concepts and principles that reinforce better
comprehension of complex concepts in other professional Medical
Technology courses.
Prerequisite: Bacteriology
Course Outcome: At the end of the course, the student should be able to:
1. discuss accurately the historical development of immunology and
serology.
2. explain properly the mechanisms of the immune system of the body;
3. apply precisely the principles of immunology in serology and laboratory
diagnosis of specific disease through the use of serological reactions;
4. integrate competently the importance of the course in the diagnosis
and treatment of disease;
5. Manifest clearly the following values: integrity, honesty, solidarity,
love, critical thinking, empathy, religious faith, and value for life in an
Augustinian- Recoleto way.
Schedule: Section M31 : 9:00 – 12:00 NN, Monday
Section M32 : 9:00 – 12:00 NN, Friday
Section M33 : 9:00 - 12:00 NN, Wednesday
Section M34: 4:30 – 7:30 PM, Thursday
Week 1 Aug. 12-16 Orientation/Vision, Mission, and Objectives (VMO)
Week 2 Aug. 19-23 Historical Development
Week 3 Aug. 26-30 Immunity
A. Nonspecific/Natural/Innate Immunity
a.1 External Defense System
a.2 Internal Defense System
a.2.1 Cellular Defense System
a.2.2 Humoral/Soluble Factors
a.2.3 Phagocytosis
a.2.4 Inflammation
B. Specific/Acquired Immunity
b.1 Active vs Passive Immunity
b.2 Humoral vs Cell-mediated Immunity
Week 4 Sept. 2-6 The Immune Response System
A. Lymphoid System
a.1 Primary and Secondary Lymphoid Organs
a.2 B-cell Differentiation
a.3 T-cell Differentiation
a.4 Natural Killer Cells
PRELIM LONG EXAM WEEK
Week 5 Sept. 9-15 Nature of Antigen & Major Histocompatibility Complex
Week 6 Sept. 16- 21 PRELIM EXAMINATION
Week 7 Sept. 23-27 Nature of Antigen & Major Histocompatibility Complex
Week 8 Sept. 30 - Oct.4 Antibody Structure and Function
Week 9 Oct. 7 - 11 Major Classes of Immunoglobulins and
Theories of Antibody Diversities
Week 10 Oct. 14 - 18 Cytokines
MIDTERM LONG EXAM WEEK
Week 11 Oct. 21- 26 MIDTERM EXAMINATION
Week 12 Oct. 28 - Nov. 1 Complement System
1. Classical Pathway
2. Alternative Pathway
3. Lectin Pathway
Week 13 Nov. 4 - 8 Hypersensitivity
Week 14 Nov. 11 - 15 Transplantation
Week 15 Nov. 17 - 23 UNIVERSITY WEEK
Week 16 Nov. 25 - 29 Tumor Immunology
Week 17 Dec. 2 - 6 Autoimmunity
ENDTERM LONG EXAM WEEK
Week 18 Dec. 9 - 13 ENDTERM EXAMINATION
GRADING SYSTEM:
Class Standing: 40%
Quizzes/Reporting/Assignments – 40%
Long Exam – 60%
Periodic Exam: 60%
Final Grade
Prelim Grade = 30 %
Midterm Grade = 30 %
Final Grade = 40 %
______
100%
SEROIM GRADE: 70% Lecture
30% Laboratory
Textbook: Immunology and Serology: A Laboratory Perspective by Christine D. Stevens
References: Immunology and Serology in Laboratory Medicine by Mary Louise Turgeon
Laboratory Immunology and Serology by Neville Bryant
Clinical Diagnosis and Management by Laboratory Methods by John Bernard Henry
“ The quality of an individual is reflected in the standards they set for
themselves”
Prepared by: FATIMA A. MEDEL, RMT, MSMT
SEROIM54P Professor
