1601 2

601
(a) Define (any five):

(i)) Frameshift mutation

(i) Pleiotropy
(
(iii) Trisomy

(iv) Test cross

(v) Heterosis

(vi) Epistasis

(b) Give the important contribution of (any five):

(5x1=5)

(i) Carl Correns

(ii) H. J. Muller

(iii) A. Strutevant

(iv) G. H. Hardy and W. Weinberg

3
601
(w) W. Bateson and R. Punnett
(vi) H. Nilsson-Ehle

Answer the
following in one word (any
five)
(51-5)
i) Number of Barr
bodies in a fernale with
chromosomes 44 + XO

(ii) Number of gametes formed in the cross

AABbCc x aabbCc

(ii) When a purine is replaced by

another puríne
in DNA

(iv) Number of linkage groups present in

Drosophila

(v) Name a manmade cereal crop

(vi) The movement of genetic material from one

region to another within the genome

P.I.0.
 1601 4

2 Diferentiate between (any five)

(53-1:
(a) Pure line selection and mass selection

(b) Maternal inheritance and maternal effect

(c) Allopatric and sympatric speciation

(d) Sex-linked and sex-limited characters

(e) Missense and nonsense mutation

() Codominance and incomplete dominance

3 Write short notes on any three of the

following
(3x5=15)
(a) Lethal alleles

(b) Chemical mutagens

(c)
Introduction of plant species
(d) Sex
determination in humans

5
1601

ie) CIB method for detection of mutation in

Drosophila.

4
(a) What is polygenic inheritance? Explain with the
help of a cross using suitable example. Write any
three characteristic features of this mode of

inheritance. (7)

(b) Explain the origin of amphidiploid Gossypium:

hirsutum (New world cotton) and hexaploid wheat
from their progenitors with the help of suitable

crosses.
(4+4-8)

5 A mutant stock of Drosophila homozygous for three

sex linked genes -sc(scute), ec(echinus) and
cv(crossveinless) was crossed to a wild type. A
female F, heterozygous for all the three genes when
test crossed with a homozygous recessive parent, gave

the following result:

P.TO.
601 Del
befi

ntt

Phenotypic class No. of progeny

444 370

cc + SV 45
(a)

44 cV 75

50

ce sc CV 385

ec sc + 70

+ sc cv 2

ec ++ 3

(i) Which classes represent the parental types, single

cross overs and double cross overs. (3)

(ii) Determine the recombination frequencies

between each pair of genes, their order and map
the distance between the genes on the
chromosome. (6)

Define cocfficient of coincidence and

interference. Calculate the value of cocfficient

afcoincidence for the given data. (6)

(a) Compare and contrast paracentric inversion wih

nericentric inversion with the help of suitable
diagrams. (7)

() A man with type O blood marries a woman with

type AB blood. What proportion of their children

would you expect to have blood types same as

either of their parents? What are the possible blood
types of the children? Explain with the help of
cross.
(5)

(c) What is the expected sex of Drosophila with the

following chromosome arrangements? (3)

(i) 4X4A

P.T.0.

1601 8

(i) 2N3A

(ii) IX3A
 2
4509
(any five)
the follow ing
(a) Define
Criss-cross inheritance

(m) QTL inheritance

(my Transposons

(IN) Penetrance

(v) Lethal alleles (1z5=5)

linkage
(b) ) What are linkage groups? How many

groups are present in Drosophila?

(ii) What are the antigen and antibody components

of blood groups A and B?

(iii) Name a manmade cereal crop.

(iv) What do you understand by genetic drift?

(v) Define speciation.
(1z5=5)

with blood type 0 marries a woman with

man
ch A
AB Among their children, what
hlood tvpe

proportion would you expcct to have blood types

Rrents of either of the two. What proportion

would you cxpect to have blood types different

from both parents. Explain. (5)

Amutant stock of Drosophila homozygous for three

sex linked genes -sc(scute), ec (echinus) and

cvlcrossveinless) was crossed to a wild type. A

female F, heterozygous for all the three genes when

test crossed with a homozygous recessive parent, gave

the following result :

P.T.0.
 P.T.O.

4509

370

44

75

50

CC SC CV 385

CC SC 70

SC Cy 2

(i) Which classes represent the parental types, single

cross overs and double cross overs?
(3)

(ii) Determine the recombination frequencies

between each pair of genes, their order and map
the distance between the genes on the

chromosome. (6)

509

i) Deine coeticient
Coineidence
ntererence. Caleulate the value of
ot coincidenee for the given data.
coefticicnt
(6

3 (a) Explain the genic

balance theory of sex
determination in Drosophila. What is
the expected
sex of an individual with the following chromosome
arrangements?
(8)

(i) 4X4A

(ii) 2X3A

(iii) 1X3A

(iv) 3X4 A

(v) 2X1A

(b) What is epistasis? Explain dominant and recessive

epistasis with one suitable example cach.
(7)

P.T.0.
 P.T.0.

4509
explain the
mutagens? Brietly
co

(a) What are

erop improvement.
phvsical mutagens in

in sh
mechanism of inheritance
(b) Eplain the
coiling of snails.

i
cytological basis of crossing over
(c) Explain the
(5)
maize.

Differentiate between the following (any five)

i) Deletion and duplication

(i) Auto and allopolyploidy

(ii) Test cross and back cross

(iv) 2-point and 3-point test cross

(v) Segregational and neutral petites

(vi) Gene and genotype frequency

(3x5-15)

7 pea
comb R and
s09 genes for rose Alternate
noultry, the
le walnut comb.
produce a
comb P
together condition (rrpp)
homozygous
in a possible
llcles of both be the
What would
comb.
produce a single
the
following crosses:
ratios in
phenotypes and their

RrPp
(i) RrPp X

(ii) RrPp X Rrpp

(iiü) Rrpp X rrpp

(iv) RRPP X Rrpp

(5)
(v) rrPP X RRpp

the number
are Barr bodies? What would be
(b) What
male.
human cells of normal
of such bodies in the
with Down's
Turner's syndrome and a female
(5)
syndrome.

pericentric
(c) Differentiate between para-and
inversions with suitable diagrams. (5)
 (a)In poultry, comb. AI
produce a walnut
comb P
together condition (rrpp)
homozygous
in a possible
lcles of both would be the
comb. What
produce a single following crosses:
ratios in the
phenotypes and their

RrPp
(i) RrPp X

Rrpp
(ii) RrPp X

(ii) Rrpp X rrpp

Rrpp
(iv) RRPP X
(5)
(v) rrPP X RRpp

bodies? What would be the number

(b) What are Barr
male,
such bodies in the human cells of normal
of
female with Down's
Turner's syndrome and a
(5)
syndrome.

pericentric
(c) Differentiate between para-and
inversions with suitable diagrams. (5)

4509
8
(a)
Elaborate on the
Seymour and Benzerexperi
to
ment performe
structure of gene. understand the
(b) What is sex
linked
suitable example. inheritance? Explain witk
 of this question paper.
2 All Questions carry equal marks.
3. Question No. 1is compulsory.
4. Attempt five questions in all including Question No.
1.

1. (a) Define (any five) of the following:

(i)) Pseudodominance

(ii) Frameshift mutation

P.T.O.

2
1418
(ii) Trisomy

(iv) Epigeneties

(v) Dicentric chromosome

(vi) Transposon (1x5=5)

(b) Give one contribution of (any five) of the following

(i) Carl Correns

(ii) Barbara McClintock

(ii) Sutton and Boveri

(iv) R. C. Punnett

(v) Hugo de Vries

(vi) Alfred Strutevant

(1x5=5)
(c) Fill in the blanks:

(i) Human females have

linkage
groups.
 1418 3

(ii) Double monosomy is rcprescntcd as

(iii) Short legged brccd of sheep was

narned as
by Seth Wright.

(iv) is an example of sex- linked

rccessive trait.

(v) When a gene affects many

aspects of
phenotype, it is said to be
(1x5=5)

2 Write short notes on (any five) of the

following

(i) Photoreactivation repair

(ii) Base Analogs

(ii) Dominant Epistasis

(iv) cis trans complementation test

P.T.0.

1418 4

(v) Retrotransposons

(vi) Reciprocal translocation

(vii) Mitochondrial inheritance in Ycast

(3x5=15)

3 Differentiate between (any five):

(i) Penetrance and Expressivity

(ii) Codominance and Incomplete Dominance

(ii) Test cross and Reciprocal cross

(iv) Paracentric and Pericentric inversion

(v) Allopatric and Sympatric speciation.

(vi) Down's syndrome and Klienefelter's syndrome

(3x5=15)
 (VIJDOwn's syndrome and Klienefelter's syndrome

(3x5=15)

1418 5

4. (a) In pen plant, T'all (T) is dominant over dwarf (t),

Ycllow sccd (Y) is dominant over grcen (y) and
Round sccd (R) is dominant ovcr wrinklcd sccd
(r). A homozygous dwarf, grcen and wrinkled pea
plant is crossed to a homozygous tall,
yellow and
round plant. Using forked line
method give the
genotypes and phenotypes of parents, F, and F,
progenies.
(8)

(b) Give an account of the

inheritance of Kappa
particles in Paramecium with diagrams. (7)

5. (a) In a population of 5000, cystic fibrosis is

seen in
125 individuals. How many individuals in the
population are the carrier of the gene for cystic
fibrosis?
(5)

(b) Mutations are caused by both environmental and

chemical insults. Describe how chemical mutagens
induce mutations. Give two examples of useful
induced mutations in crop improvement. (10)
P.T.0.

1418
(a) An individual heterozygous at thrcc gene loci A.
Nn. Rr is crosscd with thc
homozygous rcccssive
parcnt aa nn rr . The frequency of progeny with
different genotypes is as follows:
 (b) Mutations are caused by both environmental and
chemical insults. Describe how chemical mutagens
induce mutations. Give two examples of useful
induced mutations iF crop improvement. (10)
P.T.O.

1418

(a) An individual hetcrozygous at thrcc gcnc loci

Aa,
Nn, Rr is crosscd with the homozygous rcccssive
parcnt aa nn rr. The frcquency of progeny with
differcnt genotypes is as follows:

ANR 347

ANr 52

Anr 357

Anr 90

AnR 49

AnR 6

a NR 92

a Nr 7

Total progeny 1000

1418 7

(i) Which classes represent the parental types?

(2)
1418
(i) Which classes represcnt the parcntal types?
(2)
(iü) Which classes
reflect theoccurrence of single
cross overs and
double cross overs? (2)
(iii) Construct the genetic map of the 3 loci
involved indicating both map
distance and
Correct gene sequence.
(5)
(iv) What is the
coefficient of
coincidence
involved? Also find out the
degree of
interference.
(3)
(b) What is
Position effect? Explain with the
a suitable example. help of
(3)
(a) Explain the inheritance of skin
color in humans
(b) What do (5)
you
series? Explainunderstand
by
AB0 blood group
its
genetic basis of
inheritance.
(S)
P.T.O.

1418
8
(c) How can
you
haploidy and distinguish bctwecn the terms
produced and monoploidy? How can
utilized in plant haploids be
brecding? (s)
 SET A
BSc. (Hons.) Botany/II Sem
Unique Paper code: 32161303_OC
Paper Name: Genetics
Time: 3+1 Hours Max Marks: 75
Attempt any Four questions. All questions carry equal marks.
1. Distinguish between monogenic and polygenic inheritance. In a dihybrid cross, two
corn plants with green seedlings were crossed and in the F2 generation, 142 green and
34 purple seedlings were obtained. Find out the probable segregation ratio and also
explain the genetic basis of segregation. Write down the genotypes and phenotypes of
parents, F, and Fz plants. Briefly explain penetrance and expressivity. (6+8.75+4)

2. Describe an experiment performed in Maize that served as an evidence for cytological

basis of crossing over. Female Drosophila heterozygous for three recessive mutations e
(ebony body), st (scarlet eyes). and ss (spineless bristles) were testcrossed, and the
following progeny were obtained:
Phenotype
+ ++
Number
67
e ++ 8
e st + 68
e+ ss 347
e st ss 78
+ st + 368
+ st ss 10
++ Ss 54

(a) What indicates that the genes are linked? Using proper nomenclature,
determine the genotypes of the P and Fi parents.
(b) Determine the sequence and map distance between the genes.
(c) Calculate the coefficient of coincidence? Does it represent positive or negative
interference? Explain its significance. (6.75+12)

3. How do induced mutations differ from the spontaneous mutations? Describe the
mutagenic effects of Base analogues, UV radiations and Alkylating agents. (6.75+12)
4. With the help of labelled diagrams explain the meiotic behaviour of a paracentric
inversion heterozygote. How has polyploidy contributed towards evolution of crops?
Elaborate with any two suitable examples. (10.75+8)

5. Discuss inheritance of kappa particles in Paramecium. Explain genic balance theory of

sex determination in Drosophila. (10+8.75)

6. How deducing the structure of phage T4 rll locus led Benzer to understand the fine
structure of gene? In a population that is in Hardy-Weinberg equilibrium, the frequency
of the recessive homozygote genotype of a certain trait is 0.09. Calculate the percentage
of individuals homozygous for the dominant allele. (12.75+6)

SET- A
 SET C

Unique Paper Code : 32161303

Name of the Paper: Genetics
Name of the Course : B.Sc. (H) Botany CBCS
Semester III

Duration :3+ 1Hours Maximum Marks: 75

Attempt only four questions in all. All questions carry equal marks.

Q1 In a plant, purple flower is dominant over white flower and smooth texture is dominant over
wrinkled. When a purple flowered and smooth seeded plant is crossed to a purple flowered and
wrinkled seeded plant, one of the phenotypes in the progeny breeds true for white flowers and
wrinkled seeds. Determine the genotypes of the parents and phenotypic ratio of the progeny.
Explain is there any genetic interaction involved in the above problem. What is epigenetics?
Explain its mechanism. (18.75)
Q2. Describe molecular basis of mutation with reference to different chemical mutagens and
explain CIB method of detection of mutation. Give a detailed account of different
transposable genetic elements found in eukaryotes and prokaryotes. Differentiate between
composite & non composite transposons with diagrams. (18.75)
Q.3 Explain Creighton and MeClintock's experiment through diagrams. Calculate
recombination frequency, coefficient of coincidence, interference and determine order of
the genes from the following data obtained in a three point test cross. (ct = cut wings, cv=
cross wing, v= vermillion red eye) (18.75)

Genotype Progeny
+ + Ct 759
CV V t 766
+ V + 73
CV +Ct 80
+ V
Ct 140
CV + + 158
++ + 3-
CV V Ct
Q.4 Differentiate between maternal inheritance & maternal effect by citing one example each.
Also explain penetrance and expressivity with suitable examples. (18.75)
Q5 Under what conditions ring chromosome and Inversion bridge is formed? Explain their
formation with well labeled diagrams. Explain how polyploidy has resulted in evolution of
new crop species with at least 3 examples. (18.75)
Q6. What is Cis-Trans test for functional allelism? Write a brief account of different
conditions under which Hardy-Weinberg law of equilibrium is followed in a population citing
suitable examples. (18.75)

Set A

Unique Paper Code 32161101_0C

Name of the Paper Microbiology and Phycology
Name of the Course Botany
Deptt. Code 216
C No C1
Semester
7385 2

(ii) L. Cuenot

(iv) H. J. Muller

(v) Hugo de Vries, K. Correns, E.

Tscherma
(vi) S. Benzer

(b) Define the following terms (any 5): (19

(i) Holandric genes

(i) Allele

(iii) Chi-square test

(iv) Recon

(v) Karyotype

(vi) Allopatric speciation

(c) Expand the
following (any S) :
(i) SRY

(i) QTL

(in) 5-BU
 3
7385

(iv) FI

(v) NTG

(vi) cM

(any 3): (5x3)

) Write short notes on the following

(a) Multiple Alleles

(b) CIB experiment

test
(c) Cis-trans complementation
Paramecium
(d) Kappa particle inheritance in

(any 3) : (5x3)
3. Differentiate between the following

(a) Physical and Chemical mutagen

(b) Euploidy and Aneuploidy

(c) Dominance and Epistasis

variations
(a) Continuous and discontinuous

example.
(a) Hardy-Weinberg Law with an
Explain (8)
P.T.O.
 (C) Dominance and Epistasis
(d) Continuous and discontinuous variations

a) Explain Hardy-Weinberg Law with an example.

(8)
P.T.0.

7385 4

(b) Discuss maternal influence

with the
example. help of a

(a) Describe pre-zygotic and post-zygotic mechanien

of reproductive isolation in
Angiosperms. (8)
(b) What do you understand by
penetrance?
expressivity and
(5)
(c) Explain test cross. (2)

6. (a) Explain lethal alleles and their

inheritance with
examples.
(6)
(b) What is
chromosomal inversion? Discuss its
consequence during gamete formation. (9)

7. (a) In Drosophila, Lyra (Ly) and Stubble (Sb) are

dominant mutations located on two
on separate locl
chromosome 3. A recessive
mutation with bright
red eyes was also
shown to be on
Progeny is obtained by crossing a chromosome 3.
female who is
heterozygous for all three
homozygous for bright red
mutations to a male
mutation (br), The
 5
85
generated :
following data is
Number
Phenotype

Ly Sb br 404

+ 422

+
18
Ly
Sb br 16

Ly + br 75
+
+ Sb 59

Ly Sb + 4

+
+ br 2

() Calculate Non crossover, Single crossover

and Double crossover frequencies. (6)

(ii) Determine the correct gene sequence and

the map distance between each loci.
(3)

(ii) Calculate Coefficient of coincidence (C)

and Interference (I). (3)

P.T.O.

6
7385
genetic drift and its implications.
(b) Explain