Endre Dobó
> fibrous coat
                                            > cornea
                                            > sclera
                                         > vascular coat / uvea
         blind part of retina
                                            > choroid
             [1+1 layers]
                                            > ciliary body
                                            > iris
             ora serrata
[boundary; 9 layers reduced to 1 here]
                                         > nervous coat / retinal layer
                                            > as to the development
         optic part of retina
                                               > neural layer
             [1+9 layers]
                                               > pigment epithelium
                                            > as to the structure
                                               > blind part of retina
                                               > (ora serrata)
                                               > optic part of retina
                                                     > retina proper
main layers:
> fibrous coat / corneoscleral layer (tunica fibrosa)
         > cornea
         > (corneo-scleral junction)
         > sclera
> vascular coat / uveal layer (tunica vasculosa bulbi / uvea)
         > choroid
         > ciliary body (corpus ciliare)
         > iris
> sensory coat / nervous layer (tunica nervosa bulbi)
         > as to the development of the eyeball
                    > neural layer (str. cerebrale)
                    > pigment layer (str. pigmentosum / str. pigmenti retinae)
         > as to the anatomical structure
                    > blind part (pars coeca retinae)
                    > (ora serrata)
                    > optic part (pars optica retinae)
                             > retina proper
retina
choroid
sclera
extra-ocular muscle
layer of the afferent fibers (9.)
ganglion cell layer (8.)
inner nuclear layer (6.)
outer nuclear layer (4.)
rod and cone processes (2.)
pigment cells (1.)
choroid
sclera
> anterior one-sixth of the this main layer
> transparent
> its junction with the conjunctiva: limbus
> sensory innervation by long ciliary nerves [n. V/1]
> lacks vasculature (!)
> layers
            > corneal epithelium (epithelium corneae / epithelium anterius corneae)
                      > stratified squamous epithelium
                                  > underneath, there are no connective tissue papillae
                                  > free nerve endings from ophthalmic nerve [n. V/1.]
            > Bowman's membrane (lamina limitans anterior / membrana limitans anterior)
                      > acidophil, cell-free membrane
                      > if injured, it loses its transparency
            > substantia propria corneae
                      > stroma
                      > keratocytes
                      > highly regular form of dense collagenous tissue
            > Descemet's membrane (lamina limitans posterior)
                      > acidophil basement membrane
            > corneal endothelium / corneal mesothelium (endothelium camerae anterioris)
                      > simple squamous epithelium
> posterior five-sixths of the this main layer
> opaque
> contains few blood vessels
> provides insertion for the extra-ocular muscles
> layers
       > lamina fusca sclerae
               > thin layer with occasional melanocytes
               > may be considered articial layer on the inner surface of sclera
       > scleral stroma
               > densely collagenous, hypocellular tissue with elastic fibers
       > episcleral layer
               > connected with Tenon's capsule by fine delicate collagenous fibers
> important anatomical part
       > lamina cribrosa
               > perforated layer of the slcera for the passage of optic nerve fibers
> from external view
            > conjunctival ring
                        > beginning of the conjunctiva of the eyeball
            > scleral sulcus
> in the middle"
            > limbus corneae (corneoscleral junction)
> from internal view
            > Descemet s membrane terminates, and trabecular meshwork begins
            > iridocorneal angle (angulus iridocornealis)
                        > trabecular meshwork (spongiosa sclerae)
                                     > drainage of aqueous humor (humor aquosus)
                                     > parts
                                                 > trabecules / pectinate ligaments
                                                 > spaces of Fontana (spatia anguli iridocornealis)
                                                             > there is NO endothelial lining
                                                             > is not continuous with the canal of Schlemm
            > canal of Schlemm (sinus venosus sclerae / canalis Schlemmi)
                        > single circular vessel, lined by endothelium
                        > minute channels (venae aquosae) through the sclera lead to the episcleral venous
                                     system
corneal epithelium
conjunctival ring
substantia propria corneae
Descemet s membrane
iridocorneal angle
trabecular meshwork
canal of Schlemm
ciliary epithelium
> layers
     > suprachoroidal lamina (lamina suprachoroidea)
           > contains only a few vessels and pigment
           > houses the ciliary nerves, posterior ciliary arteries and the vorticose veins
           > perichoroidal space (spatium perichoroideale)
                > spatial system, part of which forms lymph pathways
     > vascular lamina (lamina vasculosa / lamina vascularis)
           > precapillary arterioles and postcapillary venules
     > choriocapillary layer (lamina choroidocapillaris / lamina choriocapillaris)
           > network of fenestrated capillaries
     > Bruch's membrane (lamina vitrea / lamina basalis)
           > double layer of basement membranes
                > blood-retina barrier
> anatomical structure
            > orbiculus ciliaris (pars plana)
                           > ciliary m. (m. ciliaris)
                                        > fibrae meridionales
                                        > fibrae radiales
                                        > fibrae circulares
            > corona ciliaris (pars plicata)
                           > ciliary folds (plicae ciliares)
                           > ciliary processes (processus ciliares)
                                        > aqueous humor (humor aquosus) is secreted here
                                        > zonula ciliaris [lencse függeszt készüléke]
                                                     > suspensory ligament of Zinn (fibrae zonulares)
                                                                > attached to the coronal equator of the lens
> histological structure
            > stroma corporis ciliaris
                           > loose connective tissue, with capillary network and ciliary muscles
            > epithelium (pars ciliaris retinae)
                           > outer layer is pigmented
                           > inner layer is NOT pigmented
stroma corporis ciliaris
epithelium ciliare
outer pigmented layer
inner NOT pigmented layer
ciliary processes
> anatomical structure
            > pupillary margin (margo pupillaris)
                         > lesser arterial circle of iris (circulus arteriosus iridis minor)
            > ciliary margin (margo ciliaris)
                         > greater arterial circle of iris (circulus arteriosus iridis major)
                         > pectinate ligaments (ligamenta pectinata)
                                     > among them: spaces of Fontana (spatia anguli iridocornealis)
> histological structure
            > anterior surface (endothelium camerae anterioris)
                         > discontinuous epithelium, intermingled with melanocytes and fibrocytes
            > stroma iridis
                         > constrictor m. of the pupil (m. sphincter pupillae)
                                     > innervated by parasympathetic fibers from the oculomotor n.
                         > pigmented cells (melanocytes)
                         > dilator pupillae m. (m. dilatator pupillae)
                                     > smooth muscle cells (neuroectodermal by origin) or
                                     > pigmented (!) myoepithelial cells
                                     > innervated by sympathetic fibers from the carotid plexus)
            > (membrana limitans iridis)
                         > membrana basalis
            > pigmented epithelium (str. pigmenti iridis / str. pigmentosum / pars iridica retinae)
                         > bilayered epithelium
endothelium camerae anterioris
stroma iridis
melanocytes
sphincter pupillae m.
dilatator pupillae m.
pigmented epithelium
> parts - as to the development
          > neural retina (str. nervosum / str. cerebrale retinae)
                    > 9 inner histological layers
          > pigment epithelium (str. pigmentosum retinae)
                    > 1 layer simple epithelium, which is pigmented
> parts - as to the anatomy
          > light-INsensitive part (pars coeca retinae)
                    > contains NO photoreceptors
                    > pars ciliaris retinae
                    > pars iridica retinae
          > (ora serrata - ora serrata)
                    > here reduce the 10 layers into 2 cell layer of pars
                             coeca
          > light-sensitive part (pars optica retinae)
                    > contains photoreceptors (rodes and cones)
> (1)    > str. pigmentosum / str. pigmenti retinae (pigment epithelium)
                      > pigmented epithelium
> (2)    > str. neuroepitheliale / str. bacilli et coni (rod and cone processes)
                      > processes of light-sensitive cells: rods (bacilli) and cones (coni)
> (3)    > str. limitans externum / membrana limitans externa (outer limiting membrane)
                      > formed by Müller cells (glial cells)
> (4)    > str. granulosum externum / str. nucleare externum (outer nuclear layer)
                      > somata of the photoreceptor cells
> (5)    > str. plexiforme externum (outer plexiform layer)
                      > between the receptor cells and bipolar cells
                      > between the horizontal cells and receptor cells
> (6)    > str. granulosum internum / str. nucleare internum (inner nuclear layer)
                      > neurons: bipolar and horizontal neurons, amacrine cells
                      > cell bodies of Müller cells
> (7)    > str. plexiforme internum (inner plexiform layer)
                      > between the bipolar neurons and ganglion cells
> (8)    > str. ganglionare (ganglion cell layer)
                      > ganglion cells
> (9)    > str. neurofibrarum (layer of the afferent fibers)
                      > unmyelinated optic nerve fibers
                      > here branch the retinal central blood vessels
> (10)   > str. limitans internum / mebrana limitans internum (inner limiting membrane)
                      > formed by Müller glial cells; demarcates the innermost aspect of the retina from the
                                  vitreous body
> principal refracting media of the eye
      > cornea
      > lens of eye (lens crystalina)
> non-refracting optical media of the eye
      > aqueous humor (humor aquosus)
      > vitreous body (corpus vitreum)
> ciliary process of ciliary body
> posterior chamber
> anterior chamber
> spaces of Fontana of the trabecular meshwork
         (between the pectinate ligamants)
> canal of Schlemm (sinus venosus sclerae)
> venae aquosae (small-caliber blood vessels)
> episcleral veins
> bulbar conjunctiva (conjunctiva bulbaris / conjunctiva bulbi)
         > continuous with the cornea
         > non-keratinized stratified squamous epithelium
         > connective tissue papillae
         > lamina propria
> (conjunctival fornix [fornix conjunctivae [reflection])
         > stratified columnar epithelium
> palpebral conjunctiva (conjunctiva palpebralis / conjunctiva palpebrae)
         > stratified columnar epithelium
                   > close to the fornix
                   > goblet cells occur in the outermost layer (!!!)
          > non-keratinized stratified squamous epithelium
                   > close to the anterior palpebral edge
         > small lacrimal glands may appear in the entire conjunctiva
> elastic biconvex structure
> structure
     > lens capsule (capsula lentis)
           > 10-20-mikrometer thick membrana basalis
     > anterior surface
           > subcapsular epithelium (epithelium anterius)
                > single cuboidal epithelium
     > (lens equator)
     > posterior surface
           > lens fibers (fibrae lentis)
                > epithelial cells
                        > losing their nuclei: anucleate fibers
                        > stretch between the anterior and posterior poles of the lens
                        > contain crystalline protein
the eye is partioned by the lens, suspenssory ligament and ciliary body into:
> smaller anterior compartment
           > filled with aqueous humor
                       > watery fluid, hypotonic with respect to plasma
                       > secreted by the ciliary processes of ciliary body
                       > source of nutrients for the non-vascular lens and cornea
           > parts
                       > anterior chamber (camera bulbi anterior)
                                  > bordered by cornea, iris and lens
                       > posterior chamber (camera bulbi posterior)
                                  > bordered by lens, suspensory ligament and ciliary body
> large posterior compartment
           > contains vitreous body
                       > gelatinous mass
                       > consisting of vitreous humor
                                  > 99% is water & hyaluronic acid
           > hyaloid canal / Cloquet s canal (canalis hyaloideus)
                       > hyaloid artery during embryological development
           > vitreous membrane / hyaloid membrane
                       > condensation of fibers on the surface of the vitreous body