HISTOLOGY OF THE EYE
BatariTodjaUmar
THE EYE
 Spherical structure,  25 mm in diameter
 Suspended in the bony orbital socket  6 extrinsic muscles
 Wall of the eye  3 concentric layers
 Fibrous tunic
 Vascular tunic
 Nerve tunic
SCLERA
Athickfibrouslayer,coverstheposterior5/6of
theeyeball
 Dividedinto3layers:
 Episclera
 Externallayer
 Looseconnectivetissueadjacenttotheperiorbital
fat
 Stroma(Substantiapropria)
 =Tenonscapsule
 Composedofdensenetworkofthickcollagenfibers
LaminaFushcae
 Inneraspect,adjacentto
thechoroid
 Containsofthinner
collagen&elasticfibers
 Melanocyte
Function:
Protects&maintains
theshapeandthe
volumeoftheeyeball
Corneoscleral Limbus
 Transitionalzone
betweenthecornea&
sclera
 1.52mmwide,1mm
thick
 Iridocornealangle
apparatusfortheoutflow
oftheaqueoushumor
trabecularmeshwork
Cornea
 Transparent,0.5
mmthickatthe
center,avascular,
5layers
Cornealepithelium
Nonkeratinizing
squamousepithelium
Basalcelllayergivesrise
to57superficiallayers
Freenerveendings
terminateinthis
epithelium
Adherestotheadjacent
cellsbydesmosomes
BowmansMembrane
810mthick
Composedoffinecollagen
fibrils
Barriertothespreadof
infection
Notregenerate
Cornealstroma
Constitutes90%ofthe
cornealthickness
Composedofabout60thin
lamellae
Eachlamellaeconsistof
parallelbundlesofcolagen
fibrils
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Descemetmembrane
Basallaminaof
endothelialcells
Homogen
Elastic,transparent
710m
Cornealendothelium
Asinglelayerof
squamouscells
Metabolicexchange
betweenthecornea&
aqueoushumor
Preciseregulationofthe
watercontentofthe
stromamaintainthe
transparency
Physical&metabolic
changescornealswelling
IRIS
Themostanteriorpartofthevasculartunic,forms
acontractilediaphragminfrontofthelens,a
circularapperture(pupil)changesinsizein
responsetothelightintensity.Eyecolouris
determinedbytherelativenumberofmelanocytes
Composedof4layers
Anteriorlimitingmembrane
Fibroblastic&melanocytecells
Stroma
Loosefibrocollagenoussupporttissue
Bloodvessels,nerve,melaninpigment
Sphinctermuscleofthepupil
Epitheliallayer
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Anteriornonpigmented
epithelium
 Dilatorpupillaemuscle
Posteriorpigmentepithelium
 Facestheposteriorchamberoftheeye
Cilliary Body
 Triangularshape
 Extendsfromthebaseoftheiristotheora
serrata
 2anatomicalregions
 Parsplica
 Parsplana
 Function:
 Aqueoushumorproduction
 Acomodationprocess
 Thelayersaresimilartothe
iris
 Consistof:
 Stroma
 Outerlayerofsmooth
musclecilliary
muscle
 Meridional
(longitudinal
portion)
 Radial(oblique
portion)
 Circularportion
 Innervascularregion
extendsintothe
cilliaryprocess
 Continuouswith
thevascularlayer
ofthechoroid
 Epitheliallayers
 3principalfunctions
 Secretionofaqueoushumor
 Paticipationinbloodaqueousbarrier
 Secretion&anchoringthezonulafibers
 Theinnercellslayernonpigmented
 Theoutercellslayerpigmented
CHOROID
Darkbrownvascularsheet,
0.25mmthickposteriorly,
0.1mmthickanteriorly
Liesbetweenthesclera&
retina
Supportstheretina
Containsof:
 Suprachoroidlamina
30mthick
Looseconnectivetissue
 Choroidalstroma
Numerousvenules&
arterioles
Hallerlayer(outerpart)
Sattlerlayer(innerpart
Choriocapillary
4.
Capillarylayersupportingthedeeplayeroftheretina
Diameter4060m
Thinwall
Bruchsmembrane
14mthick
Interfacebetweenthechoroid&theretinalpigmentepithelium
RETINA
10layers
1. Retinalpigmentepithelium
2. Photoreceptorcells
3. Outerlimitingmembrane
4. Outernuclearlayer
5. Outerplexiformlayer
6. Innernuclearlayer
7. Innerplexiformlayer
8. Ganglioncells
9. Nervefiberlayer
10. Innerlimitingmembrane
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Retinal Layers
Retinal Pigment Epithelium
Photoreceptor cells
REFRACTIVE MEDIA OF THE EYE
 LENS
Transparent,avascular,biconvex
Suspendedbetweentheedgesof
cilliarybodyzonulafibers
9mmindiameter,3.5mmthick
 Capsule
 Athickbasallamina
 Producedbytheanteriorlenscells
 Subcapsularepithelium
 Cuboidallayerofcells
 Onlyontheanteriorsurfaceofthelens
 Lensfibers
 Derivedfromsubcapsularepithelial
cells
 VitreousBody
Betweenthelens&theretina
Transparentgelatinousstructure
Attachtothesurroundingstructures
Mainportionishomogenousgelcontaining99%water,
collagen,hyaluronateacid
 Avascular
ACCESORY COMPONENTS OF THE EYE
 Conjunctiva
 Atranslucentmembrane
 Extendsfromcorneosclerallimbusinternalsurfaceof
theeyelid
 2layers
 Stratifiedcolumnarepithelium
 Gobletcellsmucin
 Laminapropria
 Looseconnectivetissue
 Bloodvessels&lymphaticvessels
 Palpebra
 Upper&lowereyelid
 Protectionoftheeye
 Containsof:
Skin
Orbicularisoculimuscle
Tarsalplate
Conjunctiva
Glands
 Meibomianglands
 Sebaceoustype
 Oilylayerofthetear
film
 Embeddedinthetarsal
plate
 GlandsofZeis
 Sebaceousglands
 GlandsofMoll
 Apocrinesweatglands
 GlandsofKrause
 Fornixconjunctiva
 GlandsofWolfring
 Abovethetarsalplate
Lacrimalapparatus
 Lacrimalglands
 Upperlateralsideofthe
orbit
 2parts:orbital&palpebral
parts
 1020ducts
 Severalseparatelobulesof
tubuloacinarserousglands
 Drainsintotheupperfornix
 Washoverthesurfaceof
theeye
 Tearsdrainfromtheeye
throughlacrimalpuncta
 Lacrimalcanaliculiatmedial
angle,
 Mergeintocommonlacrimal
duct
 Openintolacrimalsac,
pseudostratifiedciliated
epithelium
 Continuoustonasolacrimal
ductopentonasalcavity
belowtheinferiorturbinate