Name: hadeel Khaled mohamed
1. A 29-year-old primigravida has not had any prenatal care and shows up at
the emergency room in labor with marked vaginal bleeding. An ultrasound
scan shows placental abruption. Her hematocrit is now at 14% and she has
orthostatic hypotension. In this situation, which blood product may be
released for immediate transfusion without routine compatibility testing?
A Frozen, deglycerolized RBC's
B Group O, Rh negative packed RBC's
C RBC's lacking high incidence antigens
D Irradiated blood
E Group AB, Rh negative whole blood
2. A 40-year-old man has the sudden onset of severe hematemesis. On physical
examination he has a temperature of 37.1 C, pulse 106/minute, respiratory
rate 20/minute, and blood pressure 80/40 mm Hg. Laboratory studies show
Hgb 8.2 g/dL, Hct 24.5%, MCV 98 fL, platelet count 75,000/microliter, and
WBC count 4500/microliter. His prothrombin time is 30 seconds and partial
thromboplastin time 63 seconds. Which of the following is the best blood
product in this situation?
A Whole blood
B Cryoprecipitate
C Packed red blood cells
D Granulocytes
E Fresh frozen plasma (FFP)
Name: hadeel Khaled mohamed
3. A laboratory study is conducted to determine the optimal usage of platelets
for transfusion. The blood bank inventory along with the transfusion records
and medical records of subjects who were recipients of platelet transfusion
are reviewed. Which of the following conclusions is most likely to be made
from this study?
A Frozen storage of platelets helps increase the units available
B Platelet units carry no risk for transmission of HIV infection
C Platelet transfusions are rarely successful in patients with autoimmune
thrombocytopenia
D Pooled donor platelets are preferred over single-donor platelets
E Platelet transfusion is not indicated above a level of 10,000/microliter
4. A 55-year-old man has a history of peptic ulcer disease. He is admitted
following an episode of hematemesis in which he remembers vomiting
"about a quart" (1 liter) of dark red bloody emesis into the bathroom sink.
He is found to have orthostatic hypotension. His Hgb is 6.8 g/dL, Hct
19.8%, MCV 76 fL, platelet count 98,000/uL, and WBC count 10,100/uL.
His prothrombin time is 12.1 seconds and partial thromboplastin time 26.8
seconds. Which of the following blood products is most appropriate for this
man?
A Irradiated RBC's
B Cryoprecipitate
C Fresh frozen plasma
D Packed RBC's
E Platelet 6-pack
Name: hadeel Khaled mohamed
5. A laboratory study is conducted to determine the optimal usage of blood
products. Blood bank inventories and transfusion records are reviewed.
Blood products not used by their expiration date must be discarded. It is
observed that the shorter the shelf life of the blood product, the more likely
outdating occurs. Which of the following blood products is most likely to
outdate the quickest?
A Granulocytes
B Whole blood
C Packed red blood cells
D Platelets
E Fresh frozen plasma
6. A 16-year-old boy has had easy bruising, petechiae, and gum bleeding for
the past 2 months. On physical examination his vital signs include T 37 C, P
77/minute, RR 17/minute, and BP 110/75 mm Hg. His neurologic status is
normal. Laboratory studies show his Hgb is 12.7 g/dL, Hct 38%, platelet
count 22,000/microliter, and WBC count 5789/microliter. His prothrombin
time is 12.8 seconds, partial thromboplastin time 28 seconds, and D-dimer 0.
A bone marrow biopsy is performed and microscopic examination shows
increased megakaryocytes. A test for anti-platelet antibodies (glycoprotein
IIb/IIIa) is positive. Which of the following is the most appropriate therapy
for this patient?
A Packed RBC's
B Fresh frozen plasma
C Cryoprecipitate
D Platelets
E No blood products
Name: hadeel Khaled mohamed
7. A 15-year-old girl is diagnosed with acute lymphocytic leukemia. She is
being considered for bone marrow transplantation. However, she may then
require transfusion of multiple blood products. Use of which of the
following products or procedures is most likely to prevent HLA
alloimmunization from blood product therapy in this girl?
A Washed RBC's
B Gamma irradiation
C Leukodepletion filters
D Corticosteroid therapy
E Avoidance of blood products
8. A 23-year-old primigravida delivers a term girl infant following an
uncomplicated pregnancy. However, the placenta subsequently cannot be
completely delivered, and she develops marked vaginal bleeding. A day later
she has schistocytes noted on her peripheral blood smear. Which of the
following therapies is most useful for her eventual recovery and not for her
emergent situation?
A Platelets
B Fresh frozen plasma (FFP)
C Packed RBC's
D Vitamin K
E Cryoprecipitate
Name: hadeel Khaled mohamed
9. While driving to his next clinic visit, a 52-year-old man is involved in a
vehicular accident in which his car is struck broadside at an intersection.
Though the air bag inflates, the car rolls over, and the impact against the
door results in a large laceration to his lower leg. After transport to a local
hospital, he is found to have a Hct of 16%. Coagulation studies reveal a
prothrombin time of 16 seconds and partial thromboplastin time of 26
seconds. His platelet count is 69,000/microliter. Transfusion with which of
the following blood products is most likely to be of benefit to this man?
A Platelet packs
B Packed red blood cells
C Fresh frozen plasma
D Cryoprecipitate
E Whole blood
10.A laboratory study is conducted to determine whether cryoprecipitate or
fresh frozen plasma (FFP) is of greater use in treating different
coagulopathies. A deficiency involving which of the following coagulation
factors is most likely to be found to require FFP therapy?
A Fibrinogen
B Prothrombin
C vonWillebrand factor
D Factor VIII procoagulant activity
E Factor XIII
