Aerosols- MCQs
1. Topical pharmaceutical solutions are formulated using
   a) butane
   b) isobutene
   c) propane
   d) all of these
   Answer: d) all of these
2. The particle size for metered-dose inhalants should remain in the micrometer range and
   should be
   a) 2-8 micrometers
   b) 5-10 micrometers
   c) 10-15 micrometers
   d) 2-10 micrometers
   Answer: a) 2-8 micrometers
3. Active ingredients that may be irritating if inhaled can be used as
     a) spray
     b) foam
     c) wet stream
     d) all of these
     Answer: b) foam
4.   In Pressure filling apparatus, the pressure exerted by ____ helps in the flow of the
     propellant into the container
     a) Hydrogen
     b) Argon
     c) CFC
     d) Nitrogen
     Answer: d) Nitrogen
5.   Aerosol containers must be able to withstand pressures as high as ____ at 130 °F.
     a) 100 to 180 psig
     b) 120 to 170 psig
     c) 140 to 180 psig
     d) 140 to 200 psig
     Answer: c) 140 to 180 psig
6.   Glass used for aerosol containers is/are
     a) Uncoated glass
     b) Plastic-coated glass
     c) Both of these
     d) None of these
     Answer: c) Both of these
7.   Valves may be
     a) Continuous spray valve
     b) Metering valves
     c) Both of these
   d) None of these
   Answer: c) Both of these
8. Propellant 114 is
   a) methane derivative
   b) ethane derivative
   c) propane derivative
   d) butane derivative
   Answer: b) ethane derivative
9. Molecular formula of Dichlorotetrafluoroethane is
    a) CCl3F
    b) CCl2F2
    c) CClF2CClF2
    d) None of these
    Answer: c) CClF2CClF2
10. The compounds chosen for Liquefied-gas systems generally have boiling points
    a) below 70°F
    b) below 21°C
    c) above 70°F
    d) a and b
    Answer: d) a and b
11. The compressed gases used as aerosol propellants are
    a) nitrogen
    b) nitrous oxide
    c) carbon dioxide
    d) all of these
    Answer: d) all of these
12. The dip tubes are made from
    a) Nylon
    b) Derlin
    c) Buna-N
    d) Polyethylene
    Answer: d) Polyethylene
13. Which of the following is responsible for developing proper pressure within the
    container?
    a) Propellant
    b) Container
    c) Valve
    d) Product concentrate
    Answer: a) Propellant
14. In Pressure filling apparatus, the propellant stops flowing when the pressure of burette
    and container becomes
    a) equal
    b) 0
    c) 1
    d) none of these
    Answer: a) equal
15. Manufacture of pharmaceutical aerosols can be done by
    a) Pressure filling apparatus
    b) Cold filling apparatus
    c) Compressed gas filling apparatus
    d) All of these
    Answer: d) All of these
16. In Pressure filling apparatus, the pressure exerted by ____ helps in the flow of the
    propellant into the container
    a) Hydrogen
    b) Argon
    c) CFC
    d) Nitrogen
    Answer: d) Nitrogen
17. Metals used for aerosol containers are
    a) Tinplated steel
    b) Aluminum
    c) Stainless steel
    d) All of these
    Answer: d) All of these
18.  Aerosol containers are made up of
    a) metals
    b) glass
    c) plastic
    d) a and b
    Answer: d) a and b
19. Before use, the insulated box in cold filling apparatus should be filled with
    a) dry ice
    b) acetone
    c) ethanol
    d) a and b
    Answer: d) a and b
20. This apparatus consists of a delivery gauge. Identify
    a) Pressure filling apparatus
    b) Cold filling apparatus
    c) Compressed gas filling apparatus
    d) All of these
    Answer: c) Compressed gas filling apparatus