NONAN, MARIA WENA GRACE NONAN 09/25/2023
BSN 4B
DRUG NAME MECHANISM INDICATION/ ADVERSE EFFECT NURSING RESPONSIBILITIES
OF ACTION CONTRAINDICATION
Generic: Inhibits Indications: used to relieve CNS: Dizziness, drowsiness, tremors, BEFORE:
Ketorolac prostaglandin moderately severe pain, usually seizures Dx:
synthesis by pain that occurs after an a. Monitor for aspirin sensitivity,
Brand: Toradol decreasing an operation or other painful CV: Hypertension, flushing, syncope, asthma; patients may be
enzyme needed procedure pallor, edema, vasodilatation, CV more likely to develop
Therapeutic for thrombotic events, MI, stroke hypersensitivity to NSAIDs
class: biosynthesis; Contraindication: pregnancy D b. Monitor for pain: type,
Nonsteroidal analgesic, anti- (3rd trimester), hypersensitivity, EENT: Tinnitus, hearing loss, blurred location, intensity, ROM
anti- inflammatory, asthma, hepatic disease, peptic vision, transient burning/stinging before treatment
inflammatory anti-pyretic ulcer disease, CV bleeding Tx:
(NSAID), non- effects. GI: Nausea, anorexia, vomiting, a. Keep emergency equipment
opioid Drug to drug interaction: alcohol, diarrhea, constipation, flatulence, readily available at time of
analgesic aspirin: increased GI effects cramps, dry mouth, peptic ulcer, GI initial dose, in case of severe
Aspirin: increased ketorolac bleeding, perforation, taste change, hypersensitivity reaction
Pharmacologic: levels, contra indicated hepatitis, hepatic failure EDx:
Acetic acid Cefamandole, cefoperazone, a. Instruct patient to take with a
cefoTEtan, clopidogrel, GU: Nephrotoxicity: dysuria, full glass of water to enhance
Dosage: eptifibatide, plicamycin, hematuria, oliguria, azotemia absorption
30 mg ticlopidine, tirofiban, valproic b. Teach patient that product
acid: increased risk of bleeding HEMA: Blood dyscrasias, must be continued for
Route: IV CycloSPORINE, lithium, prolonged bleeding prescribed time to be
methotrexate, pentoxifylline, effective; to avoid aspirin,
INTEG:
probenecid: increased toxicity alcoholic beverages, other
NSAIDs, acetaminophen
Purpura, DURING:
Dx:
a. Assess patient’s eyes:
rash, redness, swelling, tearing,
itching
Tx:
a. Provide safety measures (e.g.
NONAN, MARIA WENA GRACE NONAN 09/25/2023
BSN 4B
pruritus,
adequate lighting, raised side
rails, etc.) to prevent injuries.
EDx:
sweating, a. Instruct patient to report
change in urine pattern,
weight increase, edema; pain
angioede in joints, fever, blood in urine
(indicates
nephrotoxicity);bruising,
ma, black tarry stools (indicates
bleeding)
Stevens- AFTER:
Dx:
Johnson a. Monitor for pain: type,
location, intensity, 1 hr after
treatment
syndrome, Tx:
b. Monitor for side effects.
a. Provide comfort measures
toxic (e.g. voiding before dosing,
taking food with drug, etc.) to
epidermal
help patient tolerate drug
effects.
EDx:
necrolysis a. Advice to report use to all
health care provider not to
use with other products
INTEG: Purpura, rash, pruritus,
sweating, angioedema, Stevens- unless approved by
Johnson syndrome, toxic epidermal prescriber; use for #5daysb.
necrolysis Instruct patient to verbalize
feelings and concerns.
