L8 : Pathology 1 : Pathology of
oropharyngeal and salivary gland diseases
1. What is the most common viral cause of cheilitis?
A. Syphilis B. Herpes simplex C. Staph. Aureus D. Monilia
2. Which condition is associated with Koplik’s spots in the mouth?
A. Thrush B. Catarrhal stomatitis C. Aphthous stomatitis D. Measles
3. What is the primary cause of thrush/candidiasis in the mouth?
A. Fungal infection B. Bacterial infection
C. Viral infection D. Vitamin deficiency
4. Which vitamin deficiency is commonly associated with atrophic glossitis?
A. Vitamin A B. Vitamin B2 C. Vitamin C D. Vitamin D
5. What is a common cause of dental (traumatic) ulcers on the tongue?
A. Syphilis B. Dyspepsia C. Teeth irritation D. Tuberculosis
6. Which of the following is a characteristic of a malignant ulcer on the tongue?
A. Undermined edge B. Raised everted edge C. Caseous floor D. Small shallow ulcer
7. What is Plummer-Vinson syndrome composed of?
A. Herpes simplex + candidiasis + aphthous ulcersB
B. Vitamin deficiency + stomatitis + glossitis + cheilitis
C. Syphilis + tuberculosis + gumma + ulcers
D. Iron deficiency anemia + pharyngitis + esophageal obstruction + atrophic glossitis
8. Which condition is caused by streptococcal hemolyticus and can lead to asphyxia and toxemia?
A. Catarrhal pharyngitis
B. Ludwig's angina
C. Aphthous stomatitis
D. Thrush
9. What is the primary cause of catarrhal stomatitis?
A. Viral infections
B. Surface irritants like smoking and spices
C. Bacterial infections
D. Fungal infections
10. Which of the following is a feature of a syphilitic ulcer in the tertiary stage?
A. Ulcerated chancre B. Mucous patches
C. Gummatous ulcer on the dorsum of the tongue D. Small shallow ulcers
1-B 2-D 3-A 4-B 5-C 6-B 7-D 8-B 9-B 10-C
11. Which of the following is a benign tumor of the salivary glands?
A. Squamous cell carcinoma
B. Pleomorphic adenoma
C. Mucoepidermoid carcinoma
D. Adenoid cystic carcinoma
12. What is the most common site for salivary gland duct stones (sialolithiasis)?
A. Parotid gland
B. Sublingual gland
C. Submandibular gland
D. Minor salivary glands
13. What is the behavior of Warthin’s tumor?
A. High recurrence rate
B. No recurrence or malignant transformation
C. Frequent malignant transformation
D. Common in young males
14. What is the most common complication of mumps in adult males?
A. Pancreatitis B. Mastitis C. Oophoritis D. Orchitis
15. Which of the following is a precancerous lesion for squamous cell carcinoma?
A. Haemangioma B. Leukoplakia C. Lymphangioma D. Granular cell tumor
16. Which of the following is a characteristic feature of a salivary gland duct stone?
A. Single, yellow stone with a granular surface B. Multiple, smooth stones
C. Soft, white stones D. Radiolucent stones
17. What is the most common cause of death in patients with advanced squamous cell carcinoma of
the tongue?
A. Hemorrhage B. Cachexia
C. Aspiration bronchopneumonia D. All of the above
18. Which of the following is a feature of Mickulicz disease?
A. Acute suppurative inflammation B. Viral infection of the parotid gland
C. Immune-mediated sialadenitis D. Bacterial infection of the submandibular gland
19. What is the most common site for squamous cell carcinoma of the tongue?
A. Posterior 1/3 B. Anterior 2/3 at the lateral edge
C. Dorsum of the tongue D. Tip of the tongue8
11-B 12-C 13-B 14-D 15-B 16-A 17-D 18-C 19-B
20. What is the most common site for squamous cell carcinoma of the tongue?
A. Posterior 1/3 B. Anterior 2/3 at the lateral edge
C. Dorsum of the tongue D. Tip of the tongue
21. What is the most common benign salivary gland tumor?
A. Warthin’s tumor B. Oncocytoma
C. Pleomorphic adenoma D. Mucoepidermoid carcinoma
22. Which of the following is a characteristic feature of pleomorphic adenoma?
A. Malignant transformation is common
B. Rarely recurs after surgical removal
C. Commonly occurs in the submandibular gland
D. Composed of epithelial and mesenchymal components
23. What is the cell of origin for pleomorphic adenoma?
A. Epithelial cells B. Myoepithelial cells
C. Lymphoid cells D. Oncocytic cells
24. Which of the following is true about Warthin’s tumor?
A. It is composed of cystic spaces with papillary ingrowth
B. It commonly occurs in young females
C. It has a high recurrence rate
D. It is commonly found in the submandibular gland
25. What is the characteristic microscopic feature of oncocytoma?
A. Cystic spaces with papillary ingrowth
B. Solid sheets of large cells with red granular cytoplasm
C. Loose myxoid tissue with cartilage islands
D. Lymphoid aggregates with germinal centers
26. Which of the following is a feature of pleomorphic adenoma on gross examination?
A. Well-demarcated mass with incomplete capsule
B. Pale gray surface with cleft-like spaces
C. Solid and homogenous light brown cut section
D. Encapsulated mass with lymphoid stroma
27. What is the most common site for Warthin’s tumor?
A. Submandibular gland B. Parotid gland
C. Sublingual gland D. Minor salivary glands
28. Which of the following is true about oncocytoma?
A. It has a high recurrence rate
B. It shows malignant transformation frequently
C. It is commonly found in old females
D. It is composed of loose myxoid tissue
20-B 21-C 22-D 23-B 24-A 25-B 26-A 27-B 28-C
29. Which of the following is a characteristic feature of adenoid cystic carcinoma?
A. Sheets of squamous cells
B. Microcystic spaces containing PAS-positive material
C. Solid acini with basophilic cytoplasmic granules
D. Mucus secretion with squamous cell carcinoma
30. Which of the following is a feature of mucoepidermoid carcinoma?
A. Sheets of small dark cells with microcystic spaces
B. Hyalinized stroma with PAS-positive material
C. Solid acini with basophilic cytoplasmic granules
D. Mixed tumor with adenocarcinoma and squamous cell carcinoma
31. What is the prognosis of adenoid cystic carcinoma?
A. Highly malignant
B. Intermediate
C. Less malignant
D. Benign
32. Which of the following is a characteristic of acinic adenocarcinoma?
A. Sheets of squamous cells
B. Solid acini of large round or polygonal cells with basophilic granules
C. Microcystic spaces with PAS-positive material
D. Mucus secretion with adenocarcinoma
33. What is a common gross feature of adenocarcinoma of the salivary glands?
A. Soft, well-demarcated mass
B. Grayish white cut surface with hemorrhage and necrosis
C. Cystic spaces filled with mucinous material
D. Pale gray surface with cleft-like spaces
34. Which of the following is true about mucoepidermoid carcinoma?
A. It is the least common malignant salivary gland tumor
B. It is composed of mixed adenocarcinoma and squamous cell carcinoma
C. It has a highly malignant prognosis
D. It is characterized by hyalinized stroma
29-B 30-D 31-A 32-B 33-B 34-B
