Low 2017
Low 2017
DOI 10.1111/jep.12713
ORIGINAL ARTICLE
KEY W ORDS
J Eval Clin Pract 2017; 1–9                              wileyonlinelibrary.com/journal/jep                           © 2017 John Wiley & Sons, Ltd.           1
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    Dispositionalism, a philosophical theory of causation, may help           3 | CAU SAL COMP LEXI TY —N O N ‐ L I N E A R
with such difficulties.                                                       INTERACTION AND MUTUAL
    The dispositional theory of causation proposed by Mumford and             MANIFESTATIONS
Anjum10 interprets the concept of cause as a cluster of powers, or
dispositions, orientated toward an effect. Powers can be thought of           Many causal factors have been cited in respect to low back pain onset
as the causal component of the properties of things. For example, a           and maintenance. Examples include cognitive factors (negative beliefs,
wine glass has a disposition of fragility. The glass has certain properties   fear avoidance behaviours, catastrophising, hypervigilance, and poor
that could causally explain why it may break if it were to fall to the        pacing),22 psychological and emotional factors (anxiety, depression,
ground because of the material from which it is made. However, the            stress, and maladaptive coping strategies),23 physical factors (pain
fact that the glass has fallen onto the floor does not necessarily mean       provocative postures and movement behaviours and muscle guarding
that it will break. Other causal powers may interrupt, counteract, or         and deconditioning),17 lifestyle factors (inactivity, social withdrawal,
intervene. The effect is reached when a single or combination of              sedentary behaviours, and sleep deficits),24–26 and environmental
dispositions exceed a threshold. This can be graphically represented          factors that include socioeconomic factors,2 negative childhood experi-
as a vector model.                                                            ences, and allostatic load.6 All of these factors may coexist, are context
    The purpose of this paper is not to compare or contrast                   dependent, and interact in a nonlinear fashion. In contrast, a traditional
philosophical accounts of causation or to offer robust accounts of            Humean view of causation favours empirical‐based observations that
                                                             11
causal explanation beyond those in the current literature.        However,    are seen with regularity, temporal asymmetry and occur together with
this paper does attempt to describe how a dispositional theory of             respect to time and space. This Humean view is one that sees the same
causation has been beneficial for the author in its utility in clinical       cause producing the same effect and therefore, in a healthcare context,
practice and that it may benefit from further research and                    the same treatment would provide the same effect in each clinical
development in the future.                                                    encounter. The complex interactions of causal relationships are not
                                                                              accounted for and can only be seen as correlations. Causation in clinical
                                                                              practice simply cannot be reduced this way into regular and linear
2   |   DIAGNOSIS AND CAUSAL CLAIMS                                           observable events. Such complexity in clinical practice requires a differ-
                                                                              ent ontological view of causation.25 Mumford and Anjum10 describe
Diagnosing conditions is regarded as an essential element of medical          that dispositions, or powers, can exist unmanifested but through inter-
practice,12 and correspondingly acquiring an acceptable diagnosis is a        action with other dispositions can facilitate causal processes to be initi-
significant feature within the patient’s illness experience that offers       ated. Therefore, no causal factor or mutual manifestations necessitate
practicality, provides psychological reassurance, and provides social         an effect. A disposition can lead to a number of different effects, depend-
acceptance.13 Diagnosis effectively ascribes a causal claim, which sug-       ing on their causal context. This theory and model favours uniqueness,
gests a biomedical explanation of illness, whereby the illness can be         context sensitivity, and holism, in contrast with the traditional reduction-
controlled and treated14 with the potential for subsequent optimism           ist medical approach. A model that successfully conveys this is the vector
and hope about the future. Additionally, diagnosis has legal and political    model (Figure 1).
implications giving individuals the opportunity to access welfare bene-           The vector model provides an overview of the causal powers that
fits. It also plays a significant social function by validating illness.15    act in a specific situation. They convey the relative strengths of power
Diagnosis is therefore of exceptional importance in the management            indicated by a vector’s length in relation to each other and direction
of medical conditions. Non‐specific low back pain is defined as low back      towards or away from the manifestation of an effect or not. The overall
pain not attributable to a recognisable, known specific pathology (eg,        tendency is a composition of all the powers that mutually manifest in a
infection, tumour, osteoporosis, fracture, structural deformity, inflam-      given context.
matory disorder, radicular syndrome, or cauda equina syndrome). By
its very definition, a biomedical causal claim is contested.16 However,
commonly in clinical practice, back pain is considered from a purely bio-
medical perspective17 despite poor associations between radiological
imaging and symptoms.18,19 On the one hand, having a diagnosis of
exclusion (eg, cancer) is reassuring,20 but, on the other, diagnostic
uncertainty remains where the cause of the pain is unknown, which
appears to lead to pain‐related guilt, disability, and depression.21 Jarvik
et al17 completed a 3‐year prospective study to determine predictors of
new onset of low back pain by reimaging 148 subjects via magnetic res-
onance imaging (MRI). They did not find a relationship between MRI
scan structural changes and first onset of low back pain but did find that
                                                                              FIGURE 1     Example of the vector model.10 The solid vertical line
depression was an independent predictor of first onset of low back
                                                                              indicates the starting situation, F and G represent 2 qualitative
pain, rather than effect. This study is an example of the difficulty in       outcomes, and T is a certain threshold effect. The arrows show causal
establishing perceived causal relationships and the nature of their           factors that dispose towards or away from the threshold effect. The
interactions.                                                                 thick arrow R represents the overall tendency of the situation
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5 | T HE I M P O R TA N C E OF A P E R S O N’ S                             perspectives of the clinician and the patient but is initiated from the cli-
NARRATIVE: A COLLABORATIVE APPROACH                                         nician’s perspective initially. However, it is important to discuss the
                                                                            content of the mind map in an open way with permission given to
The person’s narrative generates the context for the causal powers.         the patient to change any element, as they feel appropriate in an
Careful history taking in the spirit of motivational interviewing can       attempt to bridge the intersubjective space. This process encourages
elicit a rich story through the use of open questions, affirmations,        active listening, empathy, and openness, qualities that have been
reflective questions, and summaries.42                                      recognised as important in practitioner/patient interaction.42 Opportu-
    A systematic and appropriate physical examination evaluates the         nities to discuss the complex interaction of causal factors can be initi-
supporting and negating information regarding hypotheses related to         ated particularly in relation to tendencies rather than necessities. This
the condition. Attention is paid in particular to red flags and features    approach also reduces the risk of the patient feeling judged, which
of sinister pathology. Completion of the physical examination provides      may inhibit the therapeutic relationship and cause barriers to facilitat-
further evidence that needs to be carefully evaluated and openly            ing change.42 Establishing empathetic rapport and addressing the
discussed with the patient.                                                 patient’s issue has been associated as significant factors for facilitating
    All patients, particularly those whose symptoms are medically           behaviour change for a positive therapeutic outcome.37 Causal expla-
unexplained, require their experiences to be heard, understood, and         nation is complex, and a number of explanatory models exist in the lit-
related to. Kirkengen and Thornquist eloquently call for medicine to        erature ranging from amplification and sensitivity theories to illness
embrace the lived body that is free from objectification in favour of       behaviour and autonomic nervous system dysfunction theories.46
an approach that appraises the values and meanings of an ethically          However, without the context of the narrative to frame such explana-
informed epistemology.43 The lived body acknowledges that human             tions, they can become misunderstood, potentially threatening and
experience is embodied in the world and embraces a phenomenologi-           facilitate a negative therapeutic outcome.47 It is therefore imperative
cal view beyond subjectivity and values embodied intersubjective            that if causal powers are provided in a vector model and are to be used
communication. The bringing together of the patient’s narrative,            collaboratively with the patient as part of a reasoning process, that it is
thoughts, feelings, beliefs, and previous experiences combine with that     based upon the patient’s narrative and carefully gathered from a phys-
of the therapist. The combining and sharing of these two worlds come        ical examination. Using this method of collaborative and coconstructed
together into an intersubjective space where careful respect and            approach may support a positive patient‐therapist interaction that is
understanding are required to convey a useful, purposeful, and shared       associated with improved rehabilitation outcomes.48
clinically reasoned impression that informs further decision making
(Figure 2). Both primary and secondary intersubjective methods are
simultaneously used to engage with the patient and are explained in         6 | T H E V E C T O R M O D E L— A V A L U A B L E
detail by Øberg et al.44 and by Edwards et al.45 A mind map can help        C L I N I C A L R E A S O N I N G TO O L
communication and bridge the “intersubjective space” through the
inclusion of key aspects of the history and the dialectical reasoning       The causal factors are added to a vector model with the relative and
processes to provide a collaborative tool for both clinician and patient.   resultant tendencies towards or against the manifestation of the
The mind map acts as a bridge between the intersubjective                   current complaint. The vector model represents the current contextual
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FIGURE 3 A mindmap representing Jack’s narrative and potential relationships between them
elements at the present time through coconstruction with the patient.        was particularly difficult. In addition, his long‐term relationship with
It provides a snapshot of all known causal powers that have been             his girlfriend was ending and had become increasingly socially isolated.
elucidated through the narrative and examination, gathered from the          Jack felt that his symptoms needed to be explained through a struc-
patient’s perspective, the clinician’s clinical experience, and current      tural mechanism and focused on how his muscles around his scapula
research literature. From here, strategies can be made to facilitate         must be the cause his symptoms as a previous practitioner described
changes to affect the identified causal factors. The vector model may        him as having scapula dyskinesia. Jack had completed exercises on a
also shed light on factors that may not be amenable to physiotherapy         daily basis to correct this but they did not change his symptoms. He
and that may benefit from treatment from other healthcare profes-            had become frustrated and was anxious because each day appeared
sionals or agencies. In causal factors that are seen as modifiable, plans    to be the same with no end to his pain in sight. He suffered with poor
can be put into place with joint goal setting; for example, movement‐        sleep patterns and felt low in mood. This culminated in negative feel-
related fear may be counteracted through education, graded exposure          ings regarding the future. Jack’s movements appeared guarded with a
activities, and movement modifications. The vector model may bring           tendency to maintain upright and rigid postures, believing them to be
awareness to causal powers to both the clinician and therapist such          helpful in keeping the pain he had at current levels. To add to this,
as specific lifestyle and environmental factors, sometimes overlooked        he tended to hold his breath during low load tasks, which may increase
by alterative clinical frameworks. It is important to note that the vector   spinal loading.49 Despite this, he had maintained a good level of
model is a representation of complexity, context, tendencies, thresh-        physical activity and, although he was fearful of lifting activities, was
olds, linear/nonlinear composition, interference, strength, and direc-       keeping fit.
tion. It is not a model that merely describes causal factors, which              Initially, an exploration of Jack’s narrative of the events and
may determine causal claims.                                                 circumstances that led up to the manifestation of his symptoms was
                                                                             documented as a mind map (Figure 3). Physical examination findings
                                                                             found no loss of range or function of the cervical, thoracic, or shoulder
7   |   C A S E EX A M P L E —J A C K                                        regions; however, a tendency to increase muscle activity prior to
                                                                             movement appeared to occur. Widespread allodynia and hyperalgesia
A 25‐year‐old apprentice lift engineer presents with a two‐year history      were found on sensory testing across the upper aspect of the thoracic
of neck, scapula, and thoracic back pain with no history of injury or        spine and shoulder girdles. Neurological integrity examination was
trauma. Following investigations that included normal MRI scan imag-         normal as was upper limb power. Pain was reported as increased on
ing of the cervical, thoracic and scapulae regions, and normal blood         all movements and steady at rest.
tests, he was referred to physiotherapy. Previous physiotherapy and              A theoretical relationship between the narrative, the context, and
chiropractic intervention had not been successful. His work was very         the subsequent behaviour was explained through the mind map and
stressful due to the nature of his apprenticeship and difficulty with        then the relative powers represented on a vector model (Figure 4).
relationships with his coworkers. Just prior to the onset of symptoms,       The intensity of the powers drawn on the vector model were
his parents were undergoing a breakdown in their relationship, which         coconstructed by the therapist and the patient to bring personal and
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                                                                             The mind map and vector model can be used to recognise and make
                                                                             sense of the number of causal factors that are interrelated and could
                                                                             tend towards the effect of widespread pain.
                                                                                 Other treatment strategies included focusing on Jack’s social
                                                                             interaction with friends and incorporating physical activity in these
                                                                             environments. Jack started boxing training and spent time outside of
                                                                             home and college. These addressed many of the modifiable causal
                                                                             factors in a way to counteract them (reduce stress, fear and anxiety,
                                                                             and reframe beliefs), subtract (pain provocative movement), and
                                                                             interrupt through an improved understanding of pain relieving use of
                                                                             pharmacology such as analgesics, nonsteroidal anti‐inflammatories
                                                                             and neuropathic medications.
                                                                                 The outcomes resulted in self‐reported improvements in pain
                                                                             scores and sleep quality, stress, fear of movement, improved social
                                                                             interaction, and physical activity as well as self‐reported improved
                                                                             confidence and self efficacy. The vector model now shows how the
                                                                             resultant vector (R) is reduced and lies under the threshold (T)
                                                                             (Figure 5).
                                                                                 Jack’s symptoms are improved, in so much as he no longer has
FIGURE 4     A vector model used for Jack in clinical practice and is
relevant at the initial assessment. Causal vectors (a) chronic stress; (b)   constant pain; however, his symptoms can and do return through a
fear of movement; (c) sleep; (d) anxiety; (e) negative beliefs; (f) mood/    potential number of causal ways. One can see that a small change in
depression; (g) social support; (h) negative previous experiences            a single or a number of causal factors (vectors a‐h) can make the resul-
(questionably modifiable) (i) physical activity. Resultant vector (R);       tant vector (R) surpass the threshold (T) and Jack’s constant pain
threshold (T)
                                                                             returns. The variation of his symptoms could be explained though by
                                                                             the complex interrelationships of causal factors. Such variation is
shared meaning. Long term stress, fear of movement, poor sleep, anx-         understandably concerning, when one feels changes in pain through
iety and fear of the future, negative beliefs, lowness in mood, challeng-    no discernable mechanism, but the vector model can convey this mes-
ing social circumstances, poor self efficacy, and negative experiences       sage, and it can be very reassuring.
were plotted a causal relationships that tended towards the manifesta-
tion of Jack’s symptoms as all made his symptoms worse. These causal
powers have been identified in patients with persistent pain.17,22,23,35
Jack’s levels of physical activity were felt to tend away from his symp-
toms. Jack felt better for exercising, even if, as he thought, it was
because he was distracted. Figure 4 shows the resultant vector (R)
has passed the threshold (T) and is beyond the threshold. In this case,
improving just one causal relationship, or indeed, a number may not
be sufficient to reduce Jack’s symptoms. This may indicate a poorer
prognosis of recovery and/or a longer rehabilitation period or repre-
sent a more complex clinical presentation.
    The treatment was initiated by using educational methods and re‐
assurance with regards to the state of the tissues through describing
and detailing the results of the investigations. Pain neuroscience
education was provided within the context of Jack’s narrative paying
particular attention to central sensitisation theory.50 Factors such as
perceived threat,51 predictive, and associative learning52 were normal
responses that could be changed and eventually improve his
symptoms. Altering movement behaviours that were provocative and
modifying them to reduce the pain supported this. The addition of
using breathing control, relaxation techniques, and cognitive reframing
provided moderate pain relief, which was rewarding and motivated
Jack to continue with the treatment plan.53                                  FIGURE 5      A vector model used for Jack after 4 months of treatment.
                                                                             Note the resultant vector (R) lies below the threshold (T). (a) chronic
    It is important to note that caution was made to ensure that Jack’s
                                                                             stress; (b) fear of movement; (c) sleep; (d) anxiety; (e) negative beliefs;
experiences were not ascribed to being purely psychological in nature.       (f) mood/depression; (g) social support; (h) negative previous
This is a common feeling felt by patients with medically unexplained         experiences (questionably modifiable) (i) physical activity. A number of
symptoms where investigations have not yielded a causal explanation.         the causal vectors have changed with the exception of d and h
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    Jack reported feeling more in control of his symptoms and related        later, Jack is now exercising in the gym three times a week, achieving
the vector model to a balance scale. If circumstances “tipped the bal-       success in further education, with considerably less pain and feels
ance,” he felt confident that he could counteract (relaxation techniques     positive about the future.
and focus on breathing control), interrupt (use medication in the short
term), and subtract (pace activity) the causal factors. This was felt to
improve Jack’s self efficacy and sense of control over his condition.        8   |   CO NC LUSIO NS
In this respect, the vector model is dynamic and represents causality
as complex and situation dependent on a range of factors that vary           Philosophical considerations of causation with respect to dispositions,
contextually in time. Jack reflected on his progress and recognised          tendencies, and powers have utility in clinical practice. They facilitate
that, for him, a key element that changed his perspective was a positive     person‐centred care, holistic clinical management, and provide oppor-
change on his focus of attention. He also reflected on his experience        tunities for individualised clinical reasoning and communication. The
and felt that “there is no da vinci code” or singular mechanism that         evidence‐based medicine approach to healthcare is not derived from
would improve his situation in isolation and that he felt empowered          a scientifically neutral ontology but stem from a Humean account
to take control of his situation and explore solutions for himself. A year   for causation.4 Anjum states that the
FIGURE 6  Different ontologies motivate different scientific approaches. From Anjum51 with permission. EBM indicates evidence‐based medicine;
PCH, person‐centered healthcare
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                                                                                   eral practice. Psychol Psychother Theory Res Pract. 2009;82(2):199–217.
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ACKNOWLEDGEMEN TS
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