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P   R O   T   E   I   N
B I   O M O L   E C   U   L E
General Biology 2
Lesson 14
Synchronous Class
Learning Topic:
 Biomolecules
     1. Carbohydrates
     2. Lipids
     3. Proteins
     4. Nucleic Acid
Learning Content:
 Describe the structure of proteins, nucleic acids, lipids, and carbohydrates and relate them to
 their function
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    CARBOHYDRATE
• The term carbohydrate is itself a combination of the
  “hydrates of carbon”.
• They are also known as “Saccharides” which is a
  derivation of the Greek word “Sakcharon”
   meaning sugar.
• Some of the most common carbohydrates that we come across in our daily lives are in
  form of sugars.
    • Glucose, Sucrose, Fructose, Cellulose, Maltose.
CARBOHYDRATE
 Simple sugars are monosaccharide and disaccharides.
Monosaccharide (one saccharide)
Glucose               used in dextrose, blood sugar; the form utilized by the
                      human body
Galactose             found in milk and milk products
Fructose              found in fruits and honey
    CARBOHYDRATE
    Simple sugars are monosaccharide and disaccharides.
Disaccharides (two saccharides)
Maltose      glucose + glucose     found in malt
Sucrose      glucose + fructose    found in regular table sugar, sugarcane, and sugar
                                   beet
Lactose      glucose + galactose   found in milk and milk products
  CARBOHYDRATE
  Complex sugars are the polysaccharides
Polysaccharides (many saccharides)
Amylose            storage form of glucose in plants
Amylopectin        storage form of glucose in plants
Glycogen           storage form of glucose animal; stored in the liver and muscles
Cellulose          structural material in plants--cell wall in wood, wood fiber cannot be
                   digested
CARBOHYDRATE
CARBOHYDRATE
                      Carbohydrates
They are made from carbon, hydrogen, and oxygen.
Monomer: saccharides
Examples: rice, cereal, potatoes, fruits, pastas
Function: main energy source of the body
CARBOHYDRATE
Did you know that?
Marathon runners, tri-athletes, and other runners eat carbohydrates
for weeks leading up to a big event.
They call it “carbo-loading”. What’s the point?
As the athletes consume massive amounts of starch and pasta, the
energy begins to store up in their body, saving itself for use during the
event.
CARBOHYDRATE STRUCTURE
Carbohydrates are organic
compounds that contain only
carbon, hydrogen, and oxygen.
• contain a chain of carbons, an
  aldehyde or a ketone, and
  hydroxyl groups
• all consist of one or more smaller
  units called monosaccharides
  CARBOHYDRATE STRUCTURE
Monosaccharides can be classified by:
• the number of carbon atoms they contain:
  diose (2), triose (3), tetrose (4), pentose (5),
  hexose (6), heptose (7), and so on.
• based on whether or not they contain an
  aldehyde (aldose) or ketone (ketose)
• Or a combination of these 2
GLYCOSIDIC BOND
LIPIDS
•   Lipids are macromolecules made up of
    fatty acids monomers
•   Lipids play a great role in the cellular structure
    and are the chief source of energy.
•   Functions of lipids include structural support for
    the cell, energy storage and cell signalling.
•   Are non-pilar and do not interact with water.
LIPIDS
Fat and oil are the most common examples of lipids.
They are under triglycerides because they are composed of glycerol and three fatty
acids.
• Fat refers to solid triglyceride usually from animal sources such as meat, milk, butter, margarine,
  eggs, and cheese.
•   Oil refers to liquid triglycerides from plant sources. Examples are olive oil, corn oil, sunflower oil,
    and soybean oil.
ESTER BOND
                                          Lipids
•   They are made from carbon, hydrogen, and oxygen
•   They are soluble (dissolve) in oil but are insoluble in water
Examples: fats and oils
Function: long-term storage of energy in the body
Monomer: fatty acid
Two classes:
1. Saturated fats is a type of fat in which the fatty acid chains have all single bonds.
        •  Saturated fats are unhealthy fats like butter.
2. Unsaturated fats is a type of fat wherein there is at least one double bond within the
       fatty acid chain
       • Unsaturated fats are healthy, and include oils.
   PROTEIN
• Proteins are some polymers of Amino Acids.
• Proteins are found in our body as Muscles,
  Enzymes, Hormones, Antibodies and many more.
  • Food that contains proteins are Meat, Fish, Eggs, Soya.
Examples of Protein
1. Keratin is a structural protein found in hair, skin, and nails.
2. Fibroin / Silk protein - Fibroin is found in silk.
3. Collagen is a major insoluble fibrous protein found in connective tissues such as
   tendons, ligaments, skin, cartilage, and the cornea of the eye.
4. Enzymes function to catalyse chemical reactions.
    Examples of enzymes
    a. Lipase - help in digestion of fats
    b. Pepsin - help in breaking down proteins into peptides (smaller units)
    c. Sucrase - also called invertase; help in the digestion of sugars and starches
5. Myoglobin is a polypeptide that stores oxygen in muscles. It contains a heme group
   which has an iron where the oxygen is stored.
Amino Acid Structure
Essential amino acids
PEPTIDE BOND
                             Proteins
They are made from carbon, hydrogen, oxygen, and nitrogen
Proteins are made up of amino acids combined through a
dehydration link called a peptide bond.
Monomer: amino acid
There are 20 essential amino acids
NUCLEIC ACIDS
• Nucleic acids are biopolymers, or large
  biomolecules, essential to all known forms of
  life.
• They are composed of nucleotides, which
  are the monomers made of three
  components: a 5-carbon sugar, a phosphate
  group and a nitrogenous base.
• The functions of nucleic acids have to do with the storage and expression
  of genetic information.
• The two main types of nucleic acids are deoxyribonucleic acid (DNA) and
  ribonucleic acid (RNA)
NUCLEIC ACIDS
PHOSPHODIESTER BOND
                                  Nucleic Acids
They are made from carbon, hydrogen, oxygen, nitrogen, and phosphorus.
Monomer: nucleotide
Examples: DNA and RNA
Function:
• Deoxyribonucleic Acid (DNA) –storage of hereditary traits
•   Ribonucleic Acid (RNA)- protein synthesis
DNA is the blueprint of life because it contains instructions on how to make proteins in
the body.
Synthesis
Synthesis
“Take care of your body as if you were
going to live forever, and take care of your
soul as if you were going to die tomorrow.”
- St. Augustine