MELS 265
KISII UNIVERSITY
UNIVERSITY EXAMINATIONS
SECOND YEAR EXAMINATION FOR THE AWARD OF THE DEGREE OF
BACHELOR OF SCIENCE IN MEDICAL LABORATORY SCIENCE
SECOND SEMESTER 2022/2023
[JAN – APRIL, 2023]
MELS 265: MEDICAL PARASITOLOGY
STREAM: Y2 S2 TIME: 3 HOURS
DAY: THURSDAY, 9:00-12:00 P.M. DATE: 30/03/2023
INSTRUCTIONS
1. Do not write anything on this question paper.
2. Answer ALL questions in Section A and B (Compulsory). In section C, Answer
any two questions.
SECTION A Multiple Choice Questions: Attempt all questions (20 MKS)
1. The deposition of eggs in the perianal area is a characteristic of which of the
following?
A. Enterobius vermicularis
B. Fasciola hepatica
C. Ascaris lumbricoides
D. Wuchereria bancrofti
2. An intermediate host whose presence may be required for the completion of
a parasite's life cycle but in which no development of the parasite occurs.
A. Reservoir host
B. Definitive host
C. Paratenic host
D. All of these
3. Cutaneous larva migrans (CLM) occurs due to subcutaneous migration of
the ________larvae
A. Nematode
B. Cestode
C. Trematode
D. Protozoan
4. Humans are _________for S. stercoralis infections
A. Reservoir host
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B. Definitive host
C. Paratenic host
D. None of these
5. The level of a pathogen in a population, as measured in blood serum is
called ____
A. Seroprevalence
B. Prevalence
C. Mesoprevalence
D. All of these
6. Motility of Trichomonas vaginalis is described as
A. Amoeboid
B. Jerky
C. Falling leaf like
D. Stately
7. Onchocerciasis worms can be diagnosed by:
A. Examination of skin snip
B. Direct method
C. Sedimentation method
D. Floatation method
8. Leishminiasis grows intracellularly and inhibits the respiratory burst by?
A. Suppression of Th-1 response
B. Activation of Th-1 response
C. Suppression of Th-2 response
D. Shifting Th-1 to Th-2 response
9. Each of the following statements concerning Giardia lamblia is correct
except?
A. G lamblia has both a trophozoite and cyst stage in its life cycle
B. G lamblia is transmitted by the fecal-oral route from both human and
animal sources
C. G lamblia causes hemolytic anemia
D. G lamblia can be diagnosed by the string test
10. Swollen of the lymph nodes in African trypanosomiasis is called as
A. Winterbottom’s sign
B. Springbottom sign
C. Both
D. None
11. Chaga’s disease can be diagnosed by
A. Xenodiagnosis
B. Thymol turbidity test
C. Both
D. Mercuric chloride test
12. Which of the following drugs is effective against Trichomonas vaginalis?
A. Penicillin
B. Streptomycin
C. Metronidazol
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D. Pentamidine
13. The flask-shaped ulcers in the mucosa of the large intestine in humans
are caused by
A. Cryptosporidium
B. Giardia
C. Entamoeba
D. Toxoplasma
14. The unilateral conjunctivitis together with oedema of upper and lower eye
lids and cheek Trypanosoma cruzi infection is known as?
A. Romana’s sign
B. Winter bottom’s sign
C. Spring bottom’s sign
D. Summer bottom’s sign
15. Cutaneous leishmaniosis or “oriental sore” in humans is caused by
A. Leishmania donovani
B. Leishmania chagasi
C. Leishmania infantum
D. Leishmania tropica
16. The tachyzoite of Toxoplasma are
A. Crescent or banana-shaped
B. Oval shaped
C. Pear shaped
D. Rod shaped
17. Protozoal parasites belonging to class Mastigophora are characterized by
having
A. Cilia
B. Flagella
C. Cyst
D. Rhizopoda
18. Each of the following statements concerning Ascaris lumbricoides is
correct except:
A. Ascaris lumbricoides is one of the largest nematode
B. Ascaris lumbricoides can cause pneumonia
C. Both dogs and cats are intermediate host of Ascaris lumbricoides
D. Ascaris lumbricoides is transmitted by ingestion of eggs
19. Trophozoites, schizonts, and gametocytes of all the malarial parasites are
seen in the peripheral blood smear except;
A. P. falciparum
B. P. malariae
C. P. ovale
D. P. vivax
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20. Match the following dots with the Plasmodium species in which it is
prominently seen
a. Maurer’s dots I Plasmodium vivax
b. Schüffner’s dots II Plasmodium falciparum
c. Ziemann’s dots III Plasmodium ovale
d. James’ dots IV Plasmodium malariae
A. a-I, b-II, c-IIII, d-IV
B. a-II, b-I, c-IV, d-IIII
C. a-III, b-II, c-IV, d-I
D. a-II, b-I, c-IV, d-IIII
SECTION B: Attempt all questions (20 MKS)
1. Draw a well labelled diagram of G. lamblia trophozoite
2. Outline the major differences between members of sarcodina
3. Briefly, discuss transmission and control of strongydiasis
4. Discuss the pathology and pathogenesis of T.vaginalis
5. Outline laboratory diagnosis of Echinococcosis
SECTION C: Attempt any TWO questions (30MKS)
1. a) In detail, discuss the differences between the malaria species. (10 marks)
b) discuss the pathology and pathogenesis of malaria infection. (5 marks)
2. Outline the life cycle, clinical presentation and control of S.haematobium.
(15 marks)
3. Differentiate between the various Leishmania based on: (15 marks)
a) vectors
b) clinical presentation
c) form of infection
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