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Abc 4

The document provides a detailed overview of various pharmacological activities of plant extracts, including anti-cancer, anti-diabetic, anti-fertility, hair growth promoting, and neuroprotective effects. It lists specific parts of the plants used, the type of extracts, doses tested, and the cell lines or animal models involved in the studies. Each section cites relevant literature to support the findings presented.

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arpan
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7 views1 page

Abc 4

The document provides a detailed overview of various pharmacological activities of plant extracts, including anti-cancer, anti-diabetic, anti-fertility, hair growth promoting, and neuroprotective effects. It lists specific parts of the plants used, the type of extracts, doses tested, and the cell lines or animal models involved in the studies. Each section cites relevant literature to support the findings presented.

Uploaded by

arpan
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Flower 95% ethanol 50 µg/ml hydrogen peroxide [36]

80% methanol, 80% DPPH radicals [37]


ethanol

Aqueous 1 mg/ml DPPH radicals [39]

Stem Aqueous, methanolic DPPH, nitric oxide, superoxide [38]


anions, and hydrogen peroxide
radicals

Anti-cancer Oil extract 75 μg and 125 μg Oral cancer cell lines KB (ATCC [43]
CCL-17)
Leaves 90% methanol 250 µg HT-29 colorectal AGS cell lines [44]

Methanolic IC50 87.6 ± 0.91 µg/ml K-562 leukaemic cancer cells [46]
Ethyl acetate IC50 of 57.6 ± 0.61 µg/ml

Aqueous 200 µg/ml Breast MCF-7, liver HepG2, lung [47]


NCI-H23 and colon HT-29 cancer
cells

Flowers Acetone 1000 µg/ml HeLa cell lines [45]


Aqueous 2 mg/ml B16F10 melanoma cells [48]

Anti-diabetic Leaves Alcoholic NOD mice [49]


Ethanolic 2 mg/kg bw Alloxan induced diabetes in rats [51]
Methanolic 400 mg/kg Streptozotocin induced diabetic [52]
rats

Roots 500 mg/kg bw Alloxan induced diabetic type II [50]


rats
Flower Ethanolic 500 mg/kg Alloxan induced diabetes [54]
in hyperlipidemic Wister rats [55]
50, 100, and 200 mg/kg Albino rabbits
Powder Clinical trial on type II [56]
diabetes mellitus patients
aged 30- 60 years

Pharmacological Part used Extract/fraction Dose tested/route of Animals/cell line culture Literature
activity administration cited

Anti-fertility Flower Methanolic 100 mg/mL alkaline phosphatase (In vitro) [57]
Aqueous Spermatogenesis in male albino [58]
rats

Powder Propelyne glycol Albino Wister rats (inhibition of [59]


implants)
Pregnant female albino Wister rats [60]

Hair growth Leaf Petroleum ether Wister albino rats (Sonic stress [61]
promoting activity induced alopecia)
1% Male albino rats [63]
Ethanolic Male albino rats [64]
5% hydrolcholic Wister albino rats [62]
Flower Aqueous 2% Wister rats (In vitro and In vivo) [65]

Neuroprotective Root Methanolic 200 mg/kg i.p Swiss albino mice and Wistar rats [66]

300 mg/kg Male Wistar strain rats [67]

300 mg/kg Wistar albino rats with [68]


scopolamine-induced cognitive

J Ayu Herb Med ǀ Vol 4 Issue 3 ǀ July- September 2018


138

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