Proton Beam and Heavy
Plenary Session                                                                                 Spatial Fractionation (SFRT)
                                                                                    Ions Track
                                                                                                                                 FLASH in Pre-Clinical and
                            FLASH Modalities Track                           FLASH Mechanisms Track
                                                                                                                                   Clinical Settings Track
                                                                      Proton Beam and Heavy Ions & Spatial
                           FLASH Teaching Lectures                                                                              Industry Sponsored Session
                                                                            Fractionation (SFRT) Track
                                                                   Session including audience voting
                Conference Time Zone: Toronto, Ontario - Eastern Standard Time (EDT/GMT-4)
                                                                  Tuesday, 5 December 2023
    Halls                Metropolitan Ballroom West                                 Queen Quai                                               Bay
                             Welcome Words &
                          Plenary Opening Lecture:
09:00 - 09:50
                   "What Is Expected in the Field by 2030?"
                              Albert Koong (USA)
09:50 - 10:00                                                                          Short Break
                              FLASH Modalities:
10:00 - 10:30                      Protons
                             Anthony Mascia (USA)
10:30 - 10:50                                                                Coffee Break & Networking Time
                             FLASH Mechanisms
                 An Alternative Role of Oxygen in the FLASH
10:50 - 11:20
                                    Effect
                            Mirna El Khatib (USA)
11:20 - 11:30                                                                          Short Break
                       ORAL PRESENTATION SESSION 01:                     ORAL PRESENTATION SESSION 02:                       ORAL PRESENTATION SESSION 03:
11:30 - 13:00     Facility Overviews & Radiation Protection                In Vivo Pre-Clinical Studies                   Clinical Trials, TPS and Clinical Delivery
                              (FLASH Modalities I)                            (FLASH Mechanisms I)                     (FLASH in Pre-Clinical and Clinical Settings I)
13:00 - 14:15                                                                          Lunch Break
                        Proton Beams and Heavy Ions:
14:15 - 14:45                   Carbon Ions
                         Walter Tinganelli (Germany)
14:45 - 14:55                                                                          Short Break
                             FLASH Modalities
14:55 - 15:25                 VHEE/Photon I
                     Magdalena Bazalova-Carter (Canada)
15:25 - 15:40                                                                 Coffee Break in the Exhibition
                                                                                E-Poster Discussion #1-3
                                                                                     Exhibition Area
                                                                         E-Poster Station 01: FLASH Modalities I
15:40 - 16:40
                                                                        E-Poster Station 02: FLASH Mechanisms I
                                                            E-Poster Station 03: FLASH in Pre-Clinical and Clinical Settings
                                                                        ORAL PRESENTATION SESSION 04:
15:40 - 16:45                                                            Proton Beam and Heavy Ions &
                                                                           Spatial Fractionation (SFRT)
16:40-17:10                                                      Networking Time, E-Poster Viewing in the Exhibition Area
                              FLASH Mechanisms
                Ionizing Radiation‐Induced Acoustics in FLASH
17:10 - 17:40
                           and CONV Radiotherapy?
                            Julie Lascaud (Germany)
17:40 - 17:50                                                                          Short Break
                   FLASH in Pre-Clinical and Clinical Settings
17:50 - 18:20        Proton FLASH in Vivo – What Matters
                       Brita Singers Sorensen (Denmark)
18:20 - 18:30                                                                          Short Break
                      ORAL PRESENTATION SESSION 05:                 ORAL PRESENTATION SESSION 06: Highest                   ORAL PRESENTATION SESSION 07:
18:30 - 20:00            Highest Scored Absracts                               Scored Absracts                               QA and Dosimetry for the Clinic
                           (FLASH Modalities II)                            (FLASH Mechanisms II)                      (FLASH in Pre-Clinical and Clinical Settings II)
                                                                             Jingle Bells Welcome Reception
   20:00
                                                                   Exhibition Area | Open to all conference participants
                                                                             Proton Beam and Heavy
                                Plenary Session                                                                              Spatial Fractionation (SFRT)
                                                                                    Ions Track
                                                                                                                              FLASH in Pre-Clinical and
                            FLASH Modalities Track                           FLASH Mechanisms Track
                                                                                                                                Clinical Settings Track
                                                                      Proton Beam and Heavy Ions & Spatial
                           FLASH Teaching Lectures                                                                           Industry Sponsored Session
                                                                            Fractionation (SFRT) Track
                                                                 Wednesday, 6 December 2023
    Halls                Metropolitan Ballroom West                                 Queen Quai                                           Bay
07:00 - 08:00                                                                    FRPT FLASH Yoga Class
                        Spatial Fractionation (SFRT):
                 Proton Minibeam Radiobiology and Immune
08:30 - 09:00
                                  Response
                             Lorea Iturri (France)
09:00 - 09:10                                                                          Short Break
                   FLASH in Pre-Clinical and Clinical Settings
09:10 - 09:40                Clinical Perspectives
                              Alexander Lin (USA)
09:40 - 10:00                                                                Coffee Break & Networking Time
                              FLASH Mechanisms
10:00 - 10:30                Model - Oxygen Role
                               Jennifer Zou (USA)
10:30 - 10:40                                                                          Short Break
                      ORAL PRESENTATION SESSION 08:                      ORAL PRESENTATION SESSION 09:                    ORAL PRESENTATION SESSION 10:
10:40 - 12:10     Quality Assurance and Real Time Dosimetry                 In Vivo & In Vitro Studies               Mathematical Modelling & Physico-Chemistry
                             (FLASH Modalities III)                          (FLASH Mechanisms III)                           (FLASH Mechanisms IV)
                                                                                   12:20- 12:50
12:10 - 13:25                     Lunch Break                                                                                        Lunch Break
                                                                            Industry Sponsored Session
                       Proton Beams and Heavy Ions:
                 Toward Clinical Trial. From Preclinical Studies
13:25 - 14:05
                to Domestic Animals Trials and Human Patients
                        Serena Psoroulas (Switzerland)
14:05 - 14:15                                                                          Short Break
                          FLASH Teaching Lecture
14:15 - 14:45          Hypoxia and Radiation Response
                        Marianne Koritzinsky (Canada)
14:45 - 15:00                                                                 Coffee Break in the Exhibition
                                                                                E-Poster Discussion #4-6
                                                                                    Exhibition Area
                                                                        E-Poster Station 01: FLASH Modalities II
15:00 - 16:00
                                                                       E-Poster Station 02: FLASH Mechanisms II
                                                                  E-Poster Station 03: New Technologies & Mechanism
16:00-16:30                                                      Networking Time, E-Poster Viewing in the Exhibition Area
                               FLASH Modalities
16:30 - 17:00                   VHEE/Photon II
                             Vincenzo Patera (Italy)
17:00 - 17:10                                                                          Short Break
                                Debate Session:
                   Are Circulating Immune Cells the Critical
                         Factors for the FLASH Effect?
                                      For
17:10 - 17:55                 Ricky Sharma (USA)
                                    Against
                      Paula Ballesteros-Zebadúa (Mexico)
17:55 - 18:05                                                                          Short Break
                          Spatial Fractionation (SFRT):
                Cracking the Code: Microbeam RT at Ultra-High
18:05 - 18:35
                Dose Rates; the Ultimate Radiobiological Puzzle
                    Cristian Fernandez-Palomo (Switzerland)
                                                                                FLASH Networking Event
19:30 - 23:00
                                                                                 Tickets may be purchased
                                                                            Proton Beam and Heavy
                                Plenary Session                                                                                 Spatial Fractionation (SFRT)
                                                                                   Ions Track
                                                                                                                                 FLASH in Pre-Clinical and
                            FLASH Modalities Track                          FLASH Mechanisms Track
                                                                                                                                   Clinical Settings Track
                                                                     Proton Beam and Heavy Ions & Spatial
                           FLASH Teaching Lectures                                                                              Industry Sponsored Session
                                                                           Fractionation (SFRT) Track
                                                                   Thursday, 7 December 2023
    Halls                Metropolitan Ballroom West                                Queen Quai                                               Bay
                             FLASH Mechanisms
                 Multiscale Modeling of Ultrahigh Dose Rate
08:30 - 09:00
                                 Response
                           Emanuelle Scifoni (Italy)
09:00 - 09:10                                                                         Short Break
                        Proton Beams and Heavy Ions:
09:10 - 09:40                     Protons
                              Michele Kim (USA)
09:40 - 10:00                                              Coffee Break & Networking Time, E-Poster Viewing in the Exhibition
                           Spatial Fractionation (SFRT):
                Spatial Fractionation of The Dose: Getting New
10:00 - 10:30
                 Insights with Vibrational Microspectroscopy
                          Imma Martinez-Rovira (Spain)
10:30 - 10:40                                                                         Short Break
                      ORAL PRESENTATION SESSION 11:
                Quality Assurance and Real Time Dosimetry &            ORAL PRESENTATION SESSION 12:                      ORAL PRESENTATION SESSION 13:
10:40 - 12:10
                           New Horizons in FLASH                          Late-Breaking Abstracts I                          Late-Breaking Abstracts II
                            (FLASH Modalities IV)
12:10 - 12:20                                                                         Short Break
                           FLASH Teaching Lecture
12:20 - 12:50             The AI Era in Radiobiology
                            David Jaffray (Canada)
12:50 - 14:05                                                                        Lunch Break
                               FLASH Modalities
                  Exploring FLASH and Spatially Fractionated
14:05 - 14:35       Radiation Therapy (SFRT) with a X-Ray
                               Scanning System
                               John Wong (USA)
14:35 - 14:45                                                                         Short Break
                   FLASH in Pre-Clinical and Clinical Settings
14:45 - 15:15           Preclinical in Vivo- Tg Mouse
                             David Kirsch (Canada)
                                                                               E-Poster Discussion #7
15:20 - 16:20                                                                       Exhibition Area
                                                                          E-Poster Station 01: Late Breaking
16:20-16:35                                                                  Coffee Break in the Exhibition
                   FLASH in Pre-Clinical and Clinical Settings
                  Preclinical Studies to Inform the Design of
16:35-17:05
                 Early Phase Clinical Trials of UHDR in Patients
                                Lesley Jarvis (USA)
17:05-17:15                                                                           Short Break
                              Balloon Debate:
                 The Biggest Advance in Radiotherapy in the
                       Next 10 Years Will Come From..?
                                    FLASH
                         Constantinos Koumenis (USA)
                          Spatially Fractionated RT
17:15-18:15            Christian Fernandez (Switzerland)
                           Combination Treatments
                          Andrew McPartlin (Canada)
                           Artificial Intelligence (AI)
                              David Jaffray (USA)
18:15-18:30                                                                           Short Break
                             Closing Ceremony
18:30 - 19:00     Announcing the Best Oral Awards & Best E-
                               Poster Awards