P re par at ion O f MS D S

Prepared & Presented by-

Rohit Mane
Training Objectives
• What is MSDS ?
• To be familiar with MSDS.
• To understand importance of MSDS.
• To be familiar with different MSDS format.
• To be familiar with the safety signs about chemical hazards.
• For all the chemical reagents we may use daily, we need
to understand what they are made of, the hazards they
present, and how to dispose of them.
• But there are a lot of chemicals in our labs.
• Thankfully, for almost every chemical, all that
information is at our fingertips, in their Safety Data
Sheets.
• Let’s take a look at Safety Data Sheets in more detail.
We’ll cover what they are, the information within them,
and how you can use them in your lab.
What Is a Material Safety Data Sheet?

• A Material safety data sheet (MSDS) is well organised documents that contains all
information about a given chemicals.
It includes name, composition, hazards, first aid measures, fire fighting measures,
information regarding the proper steps to take with spills, handling and storage,
personal protection to be used, physical and chemical properties, and information
about stability & reactivity, toxicology, disposal, transporting, and regulatory
requirements.
MSDS is analogous to the manual of an instrument/equipment. Just look at the
manual of any household electronic item. What the manual contains? The manual
contains the manufacturer identity. Technical specification. Operating instruction.
Maintenance or trouble shooting instruction. Safety instruction etc.
Every quality software must have well organised documentation or help desk which
give all information about the software. This is also analogous to the MSDS.
When should you review a MSDS?

• Before Storing, Handling

and Working with a
chemical in any manner,
you should become
familiar with the
information provided in
the chemical’s MSDS
 Importance of MSDS-
Please observe the picture carefully, then you will get a quick overview
about the importance of MSDS. All necessary tools and guidelines are
clearly defined in MSDS to response in an emergency situation-
Standard formats of MSDS
• MSDS are available in different formats. Although the appearance are
different but the contents are almost same. We will discuss on some of
them which are most extensively followed by various industry-

• OSHA FORMAT
• ANSI FORMAT
• NFPA FORMAT
• HMIS FORMAT
 OSHA Standard For MSDS-

• The standards for MSDS specified by OSHA (Occupational Safety And Health
Administration) is organised in 9 sections. These are as-

• Section I : Supplier Information.

• Section II : Hazardous Ingredients / Identity Information.
• Section III : Physical and Chemical Properties.
• Section IV : Fire and Explosion Hazard Data.
• Section V : Reactivity Data.
• Section VI : Health Hazard Data.
• Section VII : Precautions for Safe Handling and Use.
• Section VIII : Control Measure.
• Section IX : Shipping Information.
OSHA MSDS (Example)-

Section I : Supplier Information.

Section II : Hazardous Ingredients OR

Identity Information.

Section III : Physical and

Chemical Properties.

Section IV : Fire and Explosion Hazard Data.

Section V : Reactivity Data.

Section VI : Health Hazard Data.

OSHA MSDS (Example)-

Section VII : Precautions for Safe Handling and Use.

Section VIII : Control Measure.

Section IX : Shipping Information.

OSHA Standard For MSDS-

While the format can vary, there is an Occupational Safety & Health Administration
(OSHA) recommended format that is commonly used.
− This format includes 9 sections and these are-

• Section I : Supplier Information-

It include Manufacturer’s Name and Contact Information.
- Name
- Address
- Phone
- Emergency Contact Number
- Date of MSDS was prepared
• Section II : Hazardous Ingredients / Identity Information-
- Trade Name
- Synonyms
- Chemical Abstract Service (CAS) Number
- Molecular Formula
- Molecular Weight

• Section III : Physical and Chemical Properties-

This section provides physical and chemical characteristics
- Boiling Point
- Vapor Pressure
- Vapor Density
- Specific Gravity
- Melting Point
- Evaporation Rate
- Solubility in Water
- Appearance and Odour
- pH
• Section IV : Fire and Explosion Hazard Data-
This section provide information on Fire and Explosion Hazard.
- Flash Point
- Flammable Limit
- Extinguishing Media
- Special Fire Fighting Procedure
- Unusual Fire and Explosion Hazard

• Section V : Reactivity Data-

It provides information about potential problem in mixing or storing the chemical with another.
- Stability
- Storage and Usage Condition to Avoid
- Incompatibility
- Hazardous Decomposition or By-product
- Hazardous Polymerization
• Section VI : Health Hazard Data-
- Route of Entry (Inhalation, Skin, Ingestion)
- Health Hazard (acute- immediate; chronic- build up over time)
- Carcinogenicity
- Signs and Symptoms of Exposure
- Medical Condition aggravated by Exposure
- Emergency and First Aid Procedures

• Section VII : Precautions for Safe Handling and Use-

This section have information of precautions for safe handling and use of the substance.
- Step to be taken in case Material is Released or Spilled
- Waste Disposal Material
- Precaution to be taken in Handling and Storage
- Other Precautions
• Section VIII : Control Measure-
This section provide information on control measure.
- Respiratory Protection (must be trained and fitted)
- Ventilation
- Protective Gloves
- Eye protection
- Other PPE

• Section IX : Shipping Information-

It contains detailed information on the contents of your shipment with a
technical breakdown of the components or substances in your item to prove that
it does not fall under the dangerous goods (DG) category.
ANSI Standard For MSDS-
The standards for MSDS specified by the ANSI (American National Standard Institute)
is organised in 16 sections. These are as-

• Section 01 : Product and Company • Section 09 : Physical and Chemical

Identification. Properties.
• Section 02 : Composition or Information • Section 10 : Stability and Reactivity.
of Ingredients. • Section 11 : Toxicological Information.
• Section 03 : Hazards Identification. • Section 12 : Ecological Information.
• Section 04 : First Aid Measures. • Section 13 : Disposal Considerations.
• Section 05 : Fire Fighting Measures. • Section 14 : Transportation Information.
• Section 06 : Accidental Release Measures. • Section 15 : Regulatory Information.
• Section 07 : Handling and Storage. • Section 16 : Other Information.
• Section 08 : Exposure Controls or
Personal Protection.
ANSI MSDS (Example)-

Section 01 : Product and Company Identification.

Section 02 : Composition or Information of Ingredients.

Section 03 : Hazards Identification.

Section 04 : First Aid Measures.

ANSI MSDS (Example)-

Section 05 : Fire Fighting Measures.

Section 06 : Accidental Release Measures.

Section 07 : Handling and Storage.

Section 08 : Exposure Controls or

Personal Protection.
ANSI MSDS (Example)-

Section 09 : Physical and Chemical Properties.

Section 10 : Stability and Reactivity.

Section 11 : Toxicological Information.

ANSI MSDS (Example)-

Section 12 : Ecological Information.

Section 13 : Disposal Considerations.

Section 14 : Transportation Information.

Section 15 : Regulatory Information.

Section 16 : Other Information.

 ANSI Standard For MSDS-
Hazard communication Standard 29_CFR_1910.1200 requires 16 Section that must be on
MSDS and these are-
• Section 01 : Product and Company Identification-
Identifies the chemical on the MSDS as well as the recommended uses. It also provides the
essential contact information of the chemical supplier such as contact number, Email ID,
Address, etc.
- Product Identifier. (Product name and any other common names or synonyms by
which the substance is known)
- Supplier Details. (Name, address, phone number of the manufacturer or
Importer, or other responsible party and emergency phone number).
- Recommended use of the chemical and restrictions on use.
 ANSI Standard For MSDS-
• Section 02 : Composition or Information of Ingredients-
The ingredients contained in the product indicated on the MSDS, including impurities and
stabilizing additives. This section includes information on the formulation of substances,
mixtures, and all chemicals.
• Substances
- Chemical Name, Common Name and Synonyms.
- Chemical Abstract Service (CAS) Number.

• Mixtures
- Same information requires for substances.
- The chemical and concentration (i.e. exact percentage) of all ingredients which
are classified as a health hazard.
 ANSI Standard For MSDS-
• Section 03 : Hazards Identification-
Includes the hazards of the chemical and the appropriate warning information associated with
those hazards.
- The hazard classification of chemical (e.g. flammable liquid, category-I).
- Signal word (e.g. DANGER and WARNING).
- Hazard Statement (e.g. H300: Fatal if swallowed).
- Pictograms.
- Precautionary statement (P102 Keep out of reach children).
ANSI Standard For MSDS-

▪ Oxidiser ▪ Flammable ▪ Explosive

▪ Pyrophoric ▪ Self Reactive
▪ Emit Flammable Gas ▪ Organic Peroxides

▪ Acute toxicity ▪ Corrosive ▪ Carcinogen

▪ Respiratory Sensitizer
▪ Reproductive Toxicity
▪ Mutagenicity
 ANSI Standard For MSDS-

• Section 04 : First Aid Measures-

It includes symptoms and effects and recommended treatments.
- Description of different routes of exposure (i.e. inhalation, skin and eye contact and
ingestion)
- Most important symptoms/effects and any symptoms that are acute or delayed.
- Recommendation for immediate medical care and special treatment needed, when
necessary.

• Section 05 : Fire Fighting Measures-

- Suitable and Unsuitable extinguishing media.
- Specific hazards arising from the chemicals. (during the fire, such as any hazardous
product created when the chemical burns).
- Special protective equipment's and precautions for firefighter.
 ANSI Standard For MSDS-
• Section 06 : Accidental Release Measures-
- Personal precautions, protective equipment's and emergency procedure. (Use of any
protective equipment to prevent the contamination of skin, eye and clothing during
cleanup).
- Emergency procedure, including instruction for evacuation, consulting experts when
needed and appropriate protective clothing.
- Methods and materials used for containment. (e.g. covering the drain).
- Cleanup procedure.

• Section 07 : Handling and Storage-

It include specific precautions for safe handling and storage, including incompatibility.
- Precaution for safe handling.
- Recommendation on the condition for safe storage, including specific storage
requirements. (e.g. ventilation requirements).
 ANSI Standard For MSDS-
• Section 08 : Exposure Controls or Personal Protection-
- PEL (Permissible Exposure Limit), TLV (Threshold Limit Value), OEL (Occupational
Exposure Limit), STEL (Short Term Exposure Limit) and any other exposure limit used
or recommended by the chemical manufacturer or importer.
- Appropriate engineering control. (e.g. use local exhaust ventilation or use only in an
enclosed system)
- Recommendation for personal protective measures to prevent exposure to
chemicals. (eye, skin or respiratory protection.)
-Any special requirement for PPE, protective clothing or respirators. (e.g. type of
gloves)
 ANSI Standard For MSDS-

Section 09 : Physical and Chemical Properties-

This section identifies physical and chemical properties associated with the substances or mixture.

- Appearance. - Lower Flammability Limit.

- Odor. - Upper Flammability Limit.
- Molecular Weight. - Specific Gravity.
- Flash Point. - Evaporation Rate.
- Auto ignition Temperature. - Viscosity.
- Boiling Point. - pH
- Melting Point.
- Vapor Pressure.
- Vapor Density.
- Solubility in Water.
- Flammability.
 ANSI Standard For MSDS-
• Section 10 : Stability and Reactivity-
Possibility of hazardous reaction and which conditions or materials to avoid.
- Chemical Stability. (Indication of whether the chemical is stable or unstable under normal
ambient temperature).
- Hazardous reaction or Decomposition Product.
- Possibility of hazardous reaction.
- Condition to avoid. (e.g. static discharge, shock or vibration).
- Incompatible materials.
 ANSI Standard For MSDS-
• Section 11 : Toxicological Information-
- Information of route of exposure. (Inhalation, Ingestion, Skin and Eye contact).
- Symptoms related to the physical, chemical and toxicological characteristics.
- Target Organ effect.
- Acute and also chronic effect from short and long term exposure.
▪ Route of Entry– A hazardous material may enter the body through the skin or eye or by inhalation or
ingestion.
▪ Acute Health Effect– The adverse health effect from short term exposure.
▪ Chronic Health Effect– The detrimental health conditions which may results from long term
exposure.
▪ Symptoms of exposure– A description of how victim of exposure might look or act like.
▪ Target Organ– Some materials harm a particular organ of the body. (Heart, Liver, Brain etc.)
ANSI Standard For MSDS-

Acute Oral Toxicity-

Category - Category-1 Category-2 Category-3 Category-4 Category-5

No Symbol
Pictogram-

Signal Word- Danger Danger Danger Warning Warning

Hazard Fatal if Fatal if Toxic if Harmful if May be Harmful

Statement - Swallowed Swallowed Swallowed Swallowed if Swallowed
 ANSI Standard For MSDS-
• Section 12 : Ecological Information-
Impact a spill would have on the environment.
- Ecotoxicity. (aquatic and terrestrial, where available).
- Persistence and degradability. (Is it biodegradable)
- Mobility. (Does it move in air, soil or water).

• Section 13 : Disposal Considerations-

Description of waste residue and information on their safe handling and disposal including the
disposal of any contaminated packaging.
- Recommendation for disposal if recycling is not an option.
- Description of the physical and chemical properties that may affect disposal activities.
- Direction for container disposal.
 ANSI Standard For MSDS-
• Section 14 : Transportation Information-
Safe mode of transporting the product. This section provides guidance on classification information for
shipping and transporting of hazardous chemicals by road, air, rail or sea.
- UN Number. (United Nations Number- four figure identification number of the substances)
- UN Proper shipping name.
- Transport hazard class.
- Marine pollutant (Y/N)
(Identify if it is a marine pollutant according to the
International Maritime Dangerous Goods Code IMDG Code)
- Special precaution which a user needs to be aware of or needs to comply with in connection
with transport.
 ANSI Standard For MSDS-
• Section 15 : Regulatory Information-
This section identifies the safety, health and environmental regulations specific for the product that is
not indicated anywhere else on the MSDS, Information may include-
- Any national or regional regulatory information of the chemical or mixture. (including
any OSHA, Department of Transportation, Environmental Protection Agency).
 ANSI Standard For MSDS-
• Section 16 : Other Information-
This section indicates-
- When the MSDS was prepared or when the
last known revision was made.
- Any change have been made to the previous
version and Reason.
- Other useful information.
NFPA Standard For MSDS-

• NFPA (National Fire Protection Association) has developed a system for indicating the health,
flammability and reactivity hazards of chemical in a diamond shaped object called NFPA hazard
rating diamond.

NFPA HAZARD RATING DIAMOND

 NFPA Hazard Rating-
• Colour represents kind of Hazard.
• Blue = Health
• Red = Fire/ Flammability
• Yellow = Instability
• White = Specific Hazard and
Personal Protection
• Number show degree of Hazard.
• 0 = Minimal
• 1 = Slight
• 2 = Moderate
• 3 = Serious
• 4 = Severe
• Specific Hazard =
• OX = Oxidizer
• ACID = Acid
• ALK = Alkali
• COR = Corrosive
• W = No use of Water
NFPA Hazard Rating-
 HMIS Standard For MSDS-

• HMIS (Hazardous Material Identification System) has developed a system for

indicating the health, flammability and reactivity hazards of chemical in a colour bar
called HMIS colour bar.

Rating : 0 - 4

Rating : 0 - 4

Rating : 0 - 4

Letter : A - Z
HMIS COLOUR BAR.
HMIS Standard For MSDS-

• Colour represents kind of Hazard.

• Blue = Health
• Red = Fire/ Flammability
• Orange = Physical
Hazard/Reactivity
• White = Personal Protection
• Number show degree of Hazard.
• 0 = Minimal
• 1 = Slight
• 2 = Moderate
• 3 = Serious
• 4 = Severe
 HMIS Standard For MSDS-

• Hazardous Material Identification System (HMIS) specified Personal Protective Equipment (PPE) are as-
A : Safety glasses.
B : Safety glasses and Gloves.
C : Safety glasses, Gloves and an Apron.
D : Face Shield, Gloves and an Apron.
E : Safety glasses, Gloves and a Dust Respirator.
F : Safety glasses, Gloves, Apron and a Dust Respirator.
G : Safety glasses and a Vapor Respirator.
H : Splash goggles, Gloves and Dust/Vapor Respirator.
I : Safety glasses, Gloves and Dust/Vapor Respirator.
J : Splash goggles, Gloves, Apron and Dust/Vapor Respirator.
K : Airline Hood or Mask, Gloves, Full Suit and Safety Shoes.
L-Z : Custom PPE specified by Employer.