Halcyon

system

VARIAN CONFIDENTIAL – INTERNAL USE ONLY

Varian Medical Systems
Halcyon™ Fair Balance Safety Statement

INTENDED USE SUMMARY

Halcyon™ is intended to provide stereotactic radiosurgery and precision radiotherapy for lesions, tumors, and conditions
anywhere in the body when radiation treatment is indicated.
IMPORTANT SAFETY INFORMATION
Radiation treatments may cause side effects that can vary depending on the part of the body being treated. The most
frequent ones are typically temporary and may include, but are not limited to, irritation to the respiratory, digestive, urinary
or reproductive systems, fatigue, nausea, skin irritation, and hair loss. In some patients, they can be severe. Treatment
sessions may vary in complexity and time. Radiation treatment is not appropriate for all cancers.
MEDICAL ADVICE DISCLAIMER
Varian as a medical device manufacturer cannot and does not recommend specific treatment approaches. Individual
treatment results may vary.

2 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY * Not all products or features available for sale in all markets
Halcyon™ system
Varian’s newest accelerator platform

New Standard
of Efficiency

3 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Varian’s newest accelerator platform

The 3 pillars of Halcyon™ system

• High quality of care
• Operational excellence
• Human-centered design

4 CONFIDENTIAL –PROPRIETARY:
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Definition of Halcyon

Halcyon was the

California home town
of the Varian brothers.

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Varian’s complimentary platforms
Every department has different needs.

The TrueBeam® system is designed for The Halcyon™ system is designed for operational
versatility to support a wide range of excellence and high quality image-guided IMRT
radiotherapy and radiosurgery. and RapidArc® radiotherapy technology.

6 CONFIDENTIAL –PROPRIETARY:
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Varian’s complimentary platforms

The two products are

complementary
• TrueBeam® system is optimized for
clinical versatility
• Halcyon™ system is optimized for
operational efficiency.
• TrueBeam® system DNA was used to
create the newest member of the
Varian linac family portfolio.

7 CONFIDENTIAL –PROPRIETARY:
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Varian’s complimentary platforms

With its 9 step clinical workflow,

~15sec CBCT image acquisition, and
2 RapidArc’s per minute, Halcyon™ system
is designed to be fast and easy to use with
the goal of making high quality radiotherapy
more streamlined.

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Proven architecture

Elements from TrueBeam®

• Maestro control system
• Precision engineered components
(submillimeter accuracy)
• Easy to use user interface
• Robust machine performance check
• Carbon-fiber couch top

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Halcyon™ system

Inspiration
and
Innovation
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Goals for a transformative platform
We looked at everything

Volumetric
IMRT
image RapidArc® at
treatment
acquisition in a 2 revolutions
as fast as
single breath per minute
RapidArc®
hold

Treat a patient Install the Achieve high

in 10 steps or machine in less patient
less than 2 weeks comfort

11 CONFIDENTIAL –PROPRIETARY:
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A broader definition of innovation
To solve the forthcoming challenges in radiotherapy

High
Patient
Quality
Safety
Therapy

Capital Operational
Efficiency Efficiencies

Halcyon™ system

Staff Patient
Satisfaction Experience

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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system

Workflow
Demo

•
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Simulated treatment process

14 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY Video 54
Halcyon™ system
Simulated treatment process

15 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY Video 54
Halcyon™ system

New
Technology

•
16 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Technical system overview

Gantry 100 cm bore, linear-drive ring motor

Stand Small footprint, no modulator cabinet, beam stopper

Beam 6 FFF @ 800 cGy/min
Collimation New, patented dual-layer MLC
Imaging 100% IGRT, ~15 second MV CBCT
Control System Shared with TrueBeam® system

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Halcyon™ system
Highlights

Ring gantry system

Water cooled system

Beam stopper

Imaging panel

Solid state modulator(s)

Magnetron

Linear accelerator

Dual layer multi-leaf Collimator

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Halcyon™ system
Highlights

Ring gantry system

Water cooled system

Beam stopper

Imaging panel

Solid state modulator(s)

Magnetron

Linear accelerator

Dual layer multi-leaf Collimator

19 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Highlights

Ring gantry system

Water cooled system

Beam stopper

Imaging panel

Solid state modulator(s)

Magnetron

Linear accelerator

Dual layer multi-leaf Collimator

20 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Highlights

Ring gantry system

Water cooled system

Beam stopper

Imaging panel

Solid state modulator(s)

Magnetron

Linear accelerator

Dual layer multi-leaf Collimator

21 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Highlights

Ring gantry system

Water cooled system

Beam stopper

Imaging panel
Solid state
modulator(s)
Magnetron

Linear accelerator

Dual layer multi-leaf Collimator

22 CONFIDENTIAL –PROPRIETARY:
VARIAN CONFIDENTIAL/ INTERNAL USEDISCLOSED
ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Highlights

Ring gantry system

Water cooled system

Beam stopper

Imaging panel

Solid state modulator(s)

Magnetron

Linear accelerator

Dual layer multi-leaf Collimator

23 CONFIDENTIAL –PROPRIETARY:
VARIAN CONFIDENTIAL/ INTERNAL USEDISCLOSED
ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Highlights

Ring gantry system

Water cooled system

Beam stopper

Imaging panel

Solid state modulator(s)

Magnetron

Linear accelerator

Dual layer multi-leaf Collimator

24 CONFIDENTIAL –PROPRIETARY:
VARIAN CONFIDENTIAL/ INTERNAL USEDISCLOSED
ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Highlights

Ring gantry system

Water cooled system

Beam stopper

Imaging panel

Solid state modulator(s)

Magnetron

Linear accelerator

Dual layer multi-leaf Collimator

25 CONFIDENTIAL –PROPRIETARY:
VARIAN CONFIDENTIAL/ INTERNAL USEDISCLOSED
ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Highlights

Linear accelerator

Multi-leaf collimator

Beam stopper

Imaging panel

IGRT, smooth move couch

Utility space

26 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Highlights

Linear accelerator

Multi-leaf collimator

Beam stopper

Imaging panel

IGRT, smooth move couch

Utility space

27 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Highlights

Linear accelerator

Multi-leaf collimator

Beam stopper

Imaging panel

IGRT, smooth move couch

Utility space

28 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Highlights

Linear accelerator

Multi-leaf collimator

Beam stopper

Imaging panel

IGRT, smooth move couch

Utility space

29 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Highlights

Linear accelerator

Multi-leaf collimator

Beam stopper

Imaging panel

IGRT, smooth move couch

Utility space

30 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Highlights

Linear accelerator

Multi-leaf collimator

Beam stopper

Imaging panel

IGRT, smooth move couch

Utility space

31 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Collimation subsystem

Primary
Collimator

Design features
• No jaws, large clearance
• Staggered upper/lower leaves
• 16 cm of tungsten in leaves
• Low Transmission (0.01%)
• Heavy duty drive mechanism
• 100% overtravel

32 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Collimation subsystem

Primary
Collimator

Design features
• No jaws, large clearance
Secondary
• Staggered upper/lower leaves Collimator
• 16 cm of tungsten in leaves
• Low Transmission (0.01%)
• Heavy duty drive mechanism
• 100% overtravel

33 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Collimation subsystem

Primary
Collimator

Design features
• No jaws, large clearance
Secondary
• Staggered upper/lower leaves Collimator
• 16 cm of tungsten in leaves
• Low Transmission (0.01%)
• Heavy duty drive mechanism Upper Leaf
• 100% overtravel

34 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Collimation subsystem

Primary
Collimator

Design features
• No jaws, large clearance
Secondary
• Staggered upper/lower leaves Collimator
• 16 cm of tungsten in leaves
• Low Transmission (0.01%)
• Heavy duty drive mechanism Upper Leaf
• 100% overtravel
Lower Leaf

35 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Collimation subsystem
Target

Primary
Collimator

Design features
• No jaws, large clearance
Secondary
• Staggered upper/lower leaves Collimator
• 16 cm of tungsten in leaves
• Low Transmission (0.01%)
• Heavy duty drive mechanism Upper Leaf
• 100% overtravel
Lower Leaf

36 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Collimation subsystem
Target

Primary
Collimator
Ion Chamber
Design features
• No jaws, large clearance
Secondary
• Staggered upper/lower leaves Collimator
• 16 cm of tungsten in leaves
• Low Transmission (0.01%)
• Heavy duty drive mechanism Upper Leaf
• 100% overtravel
Lower Leaf

37 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Collimation subsystem
Target

Primary
Collimator
Ion Chamber
Design features
• No jaws, large clearance
Secondary
• Staggered upper/lower leaves Collimator
• 16 cm of tungsten in leaves Fixed Outboard
Collimator
• Low Transmission (0.01%)
• Heavy duty drive mechanism Upper Leaf
• 100% overtravel
Lower Leaf

38 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Dual-layer multi-leaf collimator

39 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY Video
Halcyon™ system
Dual-layer multi-leaf collimator

40 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY Video
Halcyon™ system
The new standard for efficiency

41 CONFIDENTIAL –PROPRIETARY:
VARIAN CONFIDENTIAL/ INTERNAL USEDISCLOSED
ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
The new standard for efficiency

42 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Imaging subsystem

• 43 cm x 43 cm high-efficiency MV panel
• 7 seconds acquisition for MV/MV pair

MV Imaging –28 cm x 28 cm square (max)

• ~15 seconds acquisition for MV CBCT
–26 cm diameter x 26 cm length (max)

43 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Physics QA requirements

Applicable TG142 QA tasks

• Daily 6 of 17
• Weekly 1 of 1
• Monthly 21 of 38
• Annual 28 of 52
• Total 56 of 108 (52%) applicable

Daily MPC
• 5 minute, automated system self check
• Supplements customer QA

44 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Physics QA requirements

Solid state modulator, ambient

lighting, beam stopper

In-room touchscreen monitors

Integrated couch mounted camera

Integrated lasers

Patient intercom and noise

canceling microphone

45 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Physics QA requirements

Solid state modulator, ambient

lighting, beam stopper

In-room touchscreen monitors

Integrated couch mounted camera

Integrated lasers

Patient intercom and noise

canceling microphone

46 CONFIDENTIAL –PROPRIETARY:
VARIAN CONFIDENTIAL/ INTERNAL USEDISCLOSED
ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Physics QA requirements

Solid state modulator, ambient

lighting, beam stopper

In-room touchscreen monitors

Integrated couch mounted camera

Integrated lasers

Patient intercom and noise

canceling microphone

47 CONFIDENTIAL –PROPRIETARY:
VARIAN CONFIDENTIAL/ INTERNAL USEDISCLOSED
ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Physics QA requirements

Solid state modulator, ambient

lighting, beam stopper

In-room touchscreen monitors

Integrated couch mounted camera

Integrated lasers

Patient intercom and noise

canceling microphone

48 CONFIDENTIAL –PROPRIETARY:
VARIAN CONFIDENTIAL/ INTERNAL USEDISCLOSED
ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Halcyon™ system
Physics QA requirements

Solid state modulator, ambient

lighting, beam stopper

In-room touchscreen monitors

Integrated couch mounted camera

Integrated lasers

Patient intercom and noise

canceling microphone

49 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system

Small 2.6 m

Footprint
3.4 m
2.8 m

50 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Recommended room dimension

8.5 ft.
9 ft.

19.68 ft. 18.17 ft.

11.2 ft.
9.2 ft.

51 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Comparing footprints

100 cm 85 cm

2.6 m 2.6 m

3.4 m 4.7 m
2.8 m 2.8 m

* All dimensions are approx. and

52 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY based on publically available data.
Halcyon™ system
Value propositions

HIGH QUALITY OPERATIONAL HUMAN CENTERED

OF CARE EXCELLENCE DESIGN

53 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system

High
Quality
Care
•
54 CONFIDENTIAL –PROPRIETARY:
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High quality of care

4x Gantry
Speed

2x RapidArc® Large Bore

Optimized technology for therapy
Halcyon™ system is designed to deliver more
arcs or fields per fraction. Collimator FFF Beam
Rotation 800 Mu/Min

2x Couch
Speed

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High quality of care

Low
Leakage

100% 2x Leaf
Interdigitation Speed
New generation dual-layer MLC
For every arc or field, Halcyon™ system is
designed for more modulation and low 100% High
Overtravel Modulation
leakage.
Sharp
Penumbra

56 CONFIDENTIAL –PROPRIETARY:
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High quality of care

~15 Second
CBCT

Image 7 Second
Every Beam Mv-mv Pair
Fast, easy imaging
Halcyon™ system is designed for fast and
easy 100% IGRT. One Step Image Auto
Imaging Matching

Imaging Dose in
Plan Optimization

57 CONFIDENTIAL –PROPRIETARY:
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High quality of care

Select Collimator
Rotation in Bev
(IMRT)
9 Field IMRT
2x RapidArc®
New approach to treatment planning
Unique
Halcyon’s new system technology allows Collimator
innovative ways to achieve high clinical Rotation Thorough
Per Arc Optimization
quality.
Transverse Gantry
Target Shape (IMRT)

58 CONFIDENTIAL –PROPRIETARY:
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Preliminary plan quality assessment

Scoring ( ) vs other HW+SW systems in International Plan Challenge Competitions

100%

Contestants’ Scores 80%

60%

40%

20%

0%

59 CONFIDENTIAL –PROPRIETARY:
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Advanced stage lung
PC2012

63Gy/35fx—2012 AAMD / ROR Plan Challenge (https://www.youtube.com/watch?v=QKpc2OGtFuo)

IMRT 8F (2:27) treatment field delivery time VMAT 5PA (2:01) treatment arc delivery time

60 CONFIDENTIAL –PROPRIETARY:
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Advanced stage lung
PC2012

63Gy/35fx—2012 AAMD / ROR Plan Challenge (https://www.youtube.com/watch?v=QKpc2OGtFuo)

IMRT 8F (2:27) treatment field delivery time VMAT 5PA (2:01) treatment arc delivery time

61 CONFIDENTIAL –PROPRIETARY:
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Advanced stage lung
PC2012

63Gy/35fx—2012 AAMD / ROR Plan Challenge (https://www.youtube.com/watch?v=QKpc2OGtFuo)

IMRT 8F (2:27) treatment field delivery time VMAT 5PA (2:01) treatment arc delivery time

62 CONFIDENTIAL –PROPRIETARY:
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Breast
RTOG1005a2

63 CONFIDENTIAL –PROPRIETARY:
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Breast
RTOG1005a2

64 CONFIDENTIAL –PROPRIETARY:
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Breast
RTOG1005a2

65 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
Breast
RTOG1005a2

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SBRT spine case
From TROG-ProKnow 2017 Plan Competition

67 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
SBRT spine case
From TROG-ProKnow 2017 Plan Competition

68 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
SBRT spine case
From TROG-ProKnow 2017 Plan Competition

69 CONFIDENTIAL –PROPRIETARY:
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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
SBRT spine case
From TROG-ProKnow 2017 Plan Competition

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ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY
SBRT spine case
From TROG-ProKnow 2017 Plan Competition

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Head and neck
2017 QADS-ProKnow

72 CONFIDENTIAL –PROPRIETARY:
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Head and neck
2017 QADS-ProKnow

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Head and neck
2017 QADS-ProKnow

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Design for 100% IGRT
MV CBCT
• 3D Imaging
(~15s) MV CBCT

• 2D Imaging
(<7s) MV orthogonal pair

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Halcyon™ system

Operational
Excellence

76 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system
Total value of ownership

Connected system Latest technology

machine self-check Services Product fast RapidArc® and IMRT
integrated design ultrafast 100% IGRT

High throughput Small vault design

low maintenance Infra- embedded accessories
Finance
Structure
fast installation low electrical usage

Halcyon™ system

IT secured Human Simple, fast training

patient centric Management ease of operation
Resources
safety features reduced physics QA

77 CONFIDENTIAL –PROPRIETARY:
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Operational excellence

2-crate
Shipment

Fast Machine Easy

Assembly Transportation
Fast install/replacement
Halcyon™ system is designed to shorten
time to clinical use. Self Integrated
Shielded Subsystems

Fast
Commissioning

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Operational excellence

Consistent, Simple
Workflow

Reduced Quick
Physics QA Training
High operational value
Halcyon™ system is designed to improve
clinics’ operational value over the life of MPC and Low Electrical
Trending Usage
the system.
SmartConnect®
Enabled

79 CONFIDENTIAL –PROPRIETARY:
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Operational excellence

Consistent, Simple
Workflow

Reduced Quick
Physics QA Training
High capital efficiency
Halcyon™ system is designed to improve
hospitals’ return on investment. MPC and Low Electrical
Trending Usage

SmartConnect®
Enabled

80 CONFIDENTIAL –PROPRIETARY:
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Halcyon™ system

Human
Centered
Design
•
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Human-centered design

Quiet
Accelerator

Smooth Low Couch

Motions Height
Enhanced patient experience
Halcyon™ system is designed to enhance
patient comfort. Large Short Time
100cm Bore on Couch
Integrated
Ambient
Lighting

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Human-centered design

Patient
Verification

Collision
Enclosed
Detection
Gantry
Technology
Patient safety
Halcyon™ system is designed with a
6-point system for patient safety. 100% IGRT Daily MPC

Integrated
Camera and
Intercom

83 CONFIDENTIAL –PROPRIETARY:
VARIAN CONFIDENTIAL/ INTERNAL USEDISCLOSED
ONLY SOLELY FOR IMMEDIATE RECIPIENT ONLY