Renal Failure
Acute vs. Chronic II
Chronic Renal Failure                                          Memory Trick
                                                               - 3 Ps
 Signs & Symptoms                         !                    P - Potassium is
                                                           !   P - Priority - since it
                                                  !            P - Pumps the HEART muscles
Oliguria - LOW urine output
                                                               High potassium Over 5.0
Excess waste & electrolytes in the blood -                     HIGH PUMPS in the heart resulting in
Broken Washing machine!                                        Peaked T waves & ST Elevation
  H+ ions (Acid)                                                   Kaplan Question:
    Metabolic ACIDosis pH
    below 7.35                                                 Client with kidney disease is weak/ lethargic
  Urea                                                         and bradycardic
  Uremic frost
  Pruritus                                                        • K+ 8.5 mEq/L lab value is suspected
  HIGH Electrolytes
  Sodium Na+ HIGH (norm: 135 - 145)
                                              Sodium
                                                                  Priority Treatment
                                              Na+
  Phosphorus HIGH (norm: 3.0 - 4.5)
                                              Phosphorus
                                                P
                                                               1. IV Calcium Gluconate for Dysrhythmias
  Potassium K+ HIGH (norm: 3.5 - 5.0)
                                              Potasssium
                                              K+
                                                                      Memory trick: Gluconate GLUEs
                                                                      down heart muscles
    • Peaked T waves - 6 - 7 mEq/L                             2. IV 50% Dextrose + Regular INsulin
    • ST elevation - 7 - 8 mEq/L                               3. Kayexalate (polystyrene sulfonate)
    • Wide QRS complex - OVER 8 mEq/L                          4. Dialysis
  Kaplan Question:                                               Top 2 Missed NCLEX Questions
Patient with chronic kidney disease?                           Patient with chronic kidney disease missed 3 dialysis
      • Oliguria is expected                                   sessions… potassium level of 8.1 …
                                                               wide QRS complexes, heart rate of 58 & lethargy.
                                                               Which order should the nurse implement first?
    Critical Complications
                                                                    1. IV 50% Dextrose & regular insulin
Hypertensive Crisis                                                 2. Sodium polystyrene sulfonate
  Priority Key Signs! NCLEX TIPs!!!                                 3. Hemodialysis
      1. Headache
      2. Nausea & Vomiting                                          4. IV calcium gluconate
      3. Change in mental status
                                                               End stage renal disease… potassium 7.2, BUN 35,
Signs of Fluid Volume Overload (FVO)                           creatinine of 3.8, and urine output of 300 ml in 24
                                                               hours. Which order is PRIORITY?
• Crackles in the lungs - wet fluid filled lungs
• JVD - jugular vein distention
• Bounding pulses from that fluid excess!                             1. IV Regular insulinR & 50% Dextrose
                                                                     2. IV loop diuretic
  Anemia - Low RBCs, since kidneys release                           3. Dialysis
  Erythropoietin, the hormone that stimulates                        4. Put in for vacation time?
  bone marrow to produce red blood cells
 Renal Failure
 Acute vs. Chronic
Acute kidney failure -- sudden short -term loss of                       13
                                                                              6
                                                                                  S
                                                                                      14
                                                                                           M
                                                                                               15
                                                                                                    1
                                                                                                    8
                                                                                                        T
                                                                                                            16
                                                                                                                 W
                                                                                                                 9    10
                                                                                                                     17
                                                                                                                          T
                                                                                                                               11
                                                                                                                              18
                                                                                                                                   F
                                                                                                                                        12
                                                                                                                                       19
                                                                                                                                            S
                                                                                                                                                 Chronic Kidney Disease
kidney function. If not stopped & reversed - can
                                                                         20           21       22           23       24       25       26
                                                                         27           28       29           30
lead to Chronic Renal failure (CRD).
                                                                                           vs                                                           Stage   1      Stage   2   Stage                                        3                         Stage   4    Stage    5
Chronic kidney failure --long-term chronic                                Year 3
damage to kidneys - years & years of destruction
                                                                        Year 2
                                                                      Year 1
                                                                                                                                                                       89-            59-                                                                  29-
resulting in permanent damage                                                                                                                           90%+
                                                                                                                                                                       90%            30%                                                                  15%
                                                                                                                                                         Kidney       Kidney         Moderate
                                                                                                                                                                                                                                                           Severe      Kidney failure
   Kaplan
                                                                                                                                                        damgage      damgage         to severe
                                                                                                                                                                                                                                                           loss of    need treatment
                                                                                                                                                         normal      mild loss        loss of
                                                                                                                                                                                                                                                          function        to live
                                                                                                                                                        function    of function      function
Acute Kidney Injury … correct understanding?
 • Sudden loss of kidney function due to loss of
   the renal system circulation or glomerular/ tubular                                                                                            5 stages of CKD
   damage
                                                                                                                                                   GFR - Glomerular Filtration Rate
                                                                                                                                                     Over 90 mL/min - normal                                                                                 HESI
   Pathophysiology & Causes                                                                                                                        Stage 1: 90 + GFR
                                                                                                                                                                                                                                                          Polycystic kidney disease
                                                                                                                                                   Stage 2: 89 - 60 GFR                                                                                   • At risk for end stage
Acute Renal Failure:                                                                                                                               Stage 3: 59 - 60 GFR                                                                                     renal disease
1. Prerenal -- think decreased tissue “PRE-fusion”                                                                                                 Stage 4: 29 - 15 GFR
    • Obstruction - blocks blood flow & oxygen                                                                                                      Stage 5: 15 or Less GFR
      (emboli, clots, tumors)                                                                                                                      = End Stage Renal Disease
    • Low Blood Pressure - low perfusion
      (shock, hypovolemia, dehydration
      - from blood or volume loss); low MAP <65                                                                                                   Causes of Chronic Renal failure
    • Low Cardiac Output                                                                                                                        - Older age
                                                                                                                                                - MOST commonly tested
2. INtrarenal                                                                                                                                      - Uncontrolled Diabetes - uncontrolled HIGH sugar
     INside the renal                                    >1.3                                                                                      - Uncontrolled HTN - uncontrolled HIGH blood pressure
       • CT Contrast                                                                                                                            - Unchecked autoimmune disease - body attacks the kidney
                                            CREATININE
            Contrast kills the kidney!
       • Antibiotics
            Vancomycin
            Gentamicin                                                                                                                                                         220
       • Creatinine over 1.3 = Bad kidney
2. Post Renal -- think Past the Renal
     - Kidney stones, tumor, BPH
       Key Numbers:
          - Creatinine Over 1.3 = bad kidney                                                                                                    Diagnostics
          - BUN Over 20
          - Urine output 30 ml/hr Less = Kidneys in distress                                                                                    • Creatinine - Over 1.3 = Bad Kidney
          - Metabolic ACIDosis pH below 7.35                                                                                                    • Creatinine clearance test
                                                                                                                                                        • 24 hours - collect all urine in a container
                                                                                                                                                        • Discard the FIRST urine specimen
   Kaplan
                                                                pH < 7.35
Best indicator of good renal functions
      • 1500 mL urine in 24 hours
  4 Phases                                                                                                                                       Hesi Question
Acute Renal Failure                                                                                                                             Correct understanding of creatinine clearance test?
                                                                                                                                                Save all urine samples in a container for a designated
  1. Onset of injury (initiation)                                                                                                               period after discarding the first urine
  2. Oliguric phase - less than 400ml in 24 hours
     LOW output = thick sticky urine
  3. Diuresis phase - “Polyuric phase” - Diuresis =                                                                                                                                    URINE TEST 4              URINE TEST 5              URINE TEST 6
     drain urine 3-6 L per day!
                                                                                                                                                                                                  URINE TEST 2              URINE TEST 3
  4. Recovery phase - SLOW up to 1 year for recovery
Renal Failure
Acute vs. Chronic III
 Nursing Interventions
                                                                                                    Milk of
• Daily Weights                                                            NSAIDs                   Magnesia
       1 kg = 1 liter of fluid retained
                                                                                  AVO
• Avoid: the top drugs that can cause kidney failure
       NSAIDS                                                                         ID
       Milk of Magnesia (Anti Acid)
       Antibiotics: Vancomycin + Gentamicin                          Vancomycin   Gentamicin
       CT Contrast dye! Thick cement in washers!
  Procedures
Hemodialysis: the machine version of the kidney, used to wash the blood.
It is only used for a number of years until a kidney transplant is available.
  Diet
   • NO Sodium
        No canned / packaged foods -
        No processed meats -
   • NO Potassium                                                                              CE
                                                                                    CHOI
         Apples = BEST choice! NCLEX TIP                               BEST
         NO Salt Substitutes NCLEX TIP
         NO Leafy veggies (spinach)
                                                                                                               Potasssium
                                                                                                               K+
         NO Avocados, Carrots, Tomatoes
         NO Strawberries, Oranges or Bananas
   • Low - Phosphorus
             NO Dairy: Yogurt, Pudding, Milk NCLEX TIP
   • Low - Protein
                HESI Questions                               KAPLAN Questions
     Q: Best food choice for potassium of 6.5?
                                                           Rationale for low protein diet?
         A: Apple slices or apple juice... low K+ levels
     Q: Which statement … need for further
                                                           Answer: preserve renal function
     education?
                                                           Teaching about nutrition has been
       A: "I should reduce my sodium intake by
       using a salt substitute."
                                                           effective when the client states:
                                                           Answer: “I will eat red bell peppers
                                                           and avoid red meats”
                                                                                  AVOID