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The document contains detailed information on various blood platelet disorders, coagulation factors, and their associated conditions. It discusses the implications of different blood group antigens, antibodies, and their relevance in transfusion medicine and hemolytic disease. Additionally, it outlines laboratory testing methods and results related to coagulation and blood typing, emphasizing the complexities of blood group serology.

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0% found this document useful (0 votes)
1 views4 pages

4t (4)

The document contains detailed information on various blood platelet disorders, coagulation factors, and their associated conditions. It discusses the implications of different blood group antigens, antibodies, and their relevance in transfusion medicine and hemolytic disease. Additionally, it outlines laboratory testing methods and results related to coagulation and blood typing, emphasizing the complexities of blood group serology.

Uploaded by

Betchy Gaming
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Plt Quanti (↓) Plt pro: BSS,FA,TAR,Viral,Leu,Megal

WAS,MYH9; Plt Des HUS,DIC,ITP,TTP,HIT Spl Seq


Gau,Hodg,Sarc,Lympma,Cirrh,Port hyp; Ma Bl tra
(↑) Reac: Rec splene,Ac Bl los, Surg; Auto ET,CML,
PV, PMF Quali Adh(BSS ar,vWD ad); Agg(Gla ar,He
afi) Sec (a=Gray ar)(d=Her ar,Che,WAS xlr,TAR)
Coag 1-Fib=340k,100-150,200-400mg; <100->PT
PTT; 10/dec; 2-Prot 71.6k, 60,10; 3 Ti Fa/Thropla,
kina 44,inso,none; 4 Ca-40,N/a,8-10; 5 proac/labi
throgen-330k,24,1; 7 50k,6,0.05, Procon,Sta Fac;
8-AHF-A,AHG; 330k,12,0.01; vWF-600k-20m,24,1
9-Chri,AHF-B,PTC;57k,24,0.3; 10- stu-pr;58.8k,48-
52,1; 11-AHF-C,PTAnte;143k,48-84,0.5;>50Ashke;
Rosen->HemoC; 12 Hage/Glas/Conta;84k,48-70,3;
Thrombotic xble; 13 Fib sta/Fibrnase/Laki-320k,
150,2; 5m urea; xCoag Tests; PK-Preka(Fletc)85k,
35,35-50; HMWK Reid/Will/Fitz/Flau 120k,156,5
Fibgen:1,5,8,13; Prothro->2,7,9,10;Contact 12,11,
PK,HMWK Clotting Path 12-HMWK-11-98CaPL;
73CaPL;105CaPL; In-vivo: 3-7-10/9->10-5-2a->Plt,
8,11=8a:9a&5a:10a; PTT: PPP(15m-2500g <15k/uL
,35-45,UFH;PT:PPP;10-13; Warf; INR:2-3(+0.5 Me)
Result PT,PTT,TT,Plt; Norm, plt func, 13 def, Vasc
hem, Fiblys (NNNN); 7(PNNN); intrin/PK/HMWK;
vWF, Circu Anticoag(NPNN); Vit K, Oral
anticoag,5,10,2 (PPNN); Hepari,Liver,Fibge (PPPN)
Throcypenia (NNNL) DIC(PPPL) AC: Cou(oral,VKA,
Pro C&S;VK,FFP,PT complex, rVIIa;UFH IV,thr&10,
Prota sulf(sal sp); ACT->high UFH; LMWH ATIII->
inhi 10a but not 2a; subcuta,↓HIT,↓Herr/osteopo
Other Stypven (russ)->1,2,5,10; x7, dif 7&10 20-25;
Vipera rus; dRVVT=Lup AC(30-35); Throm Time
Fib def, aff by hep; Hep inhi; 15-18s Reptilase Bot
atrox, fibgen->fibrin, xAff by hep, 10-15s Instrum
mecha/electrome=BBL(emec->conducti) Dia Stag
(emagne->visco) Photo-op(Turb)=OD; Nephele
90d or forward li sca; xOD; Chromo(Ami) oligope,
pNA,Protease, xinhibitors interfere; Substi: aged
ser:1,5,8,2,13; Age pla:5,8; Adso Pla:2,7,9,10; FP
Stat 7 Le(a,b) W/B: +/-22/23; -+72/55; -/-6/22; 2
MnSs M+N+(50/44) S-s+(45/69) S-U-(0/<1); 3 P/28
globo P1 (79/94): P/P1 and No ab; P2k=m rare; 6
Kel K-k+(91/96.5)Kp(97.7/100)Js(a-b+)100/80; 8
Duf a+b- chi(90.8)W(a+b+49)B(a-b-68)
BGS Lew Fuco tran; adso plas; Ag:Infa(a-b-),↓preg;
Ab IgM; MNSs Ag: MN Gly A (SG-M,LQ-N,1/5) Ss (
Gly B,Ag Exp,MT-Ss 29 Ab: An-M xcomp,cold rea,
xenz RC, pH6.5, Glucose dep, Rare: HTR/HDN; An-
N Cold re IgM/G, xcomp, renal px dia w/ form;
Anti-S,s: IgG,rxn 37/AHG, Sev HTR w/ hgburi,HDN
P & Globo Ag: P1 Fetal RC(12w)F 7y,↓store,P1-like
in pla,pige/turtdo drop,eggwhi turtdi; P1-subs
hydatid (E. gran), ext of Lumbri ter, Asca suum An
An-P1 Sera P2, cold-rx,E-gran=strong, C. Sinen, F
bus, O. Vive; An-PP1Pk P-null, Anti-Tja, Rxn wide
range, Spon abor/HDN An-P Allo-an P rare,signi,
IgG in PCH, Donath Test; An-Pk An-PP1Pk sele ad
w/ P1 cells, P1 w/ cirr,AIHA I Ag Ii ↑i:Ac Leu,PNH,
Thala,Megalo an, Rx lympho An An-I Com autoab,
str rxn adult cel, weak cord; xHDN, Benign: Seru,
xIn vivo, Weak IgM, rx:40; Patho: pot IgM, Autoagg
(Reynaud) or IV hemoly; Autoanti-I Micro I-like (M.
Pneu=crossl; L. monocy CAHA ad rabb) An-i rx 4;
IgM: IM, RES(alc cir, Mye Leu, Reticu) IgG: HDN
An-IT transi i->I, Natur Mela/Yano Ind, Parasite,
Hodgki dse. Kell Ag Immunoge, Weak=Mcleod; An
Anti-K Common, Sev HTA/HDN, extravas; An-Kpa,
Jsa: few expo, unex incomp,HDN; An-k, An-Kpb,
An-Jsb few lack ag McLeod XL CGD, males only,
areflex(xtendon flex), choreiform, cardiomeg;
Duffy Ag Fya/Fyb: Fetal RC(6w), An An-Fya/Fyb
IgG AHG, ↑LISS, xEnz RC, HTR not sev; Kidd Ag:
Fetal RC (11w-JKa; 7w-Jkb), x alter enz; An Notori
repu, Imm ab (preg/transf), AHG, comm HTR del,
intra hemoly, extra->liver; Infreq/mild HDN, px rec
aldomet/methdopa autoab; Luthe Ag LuaLub
xadult until 15, poor birth; An An-Lua IgA,M,G; RT,
An-Lub Preg/tra, short sur tr cells and Post jaun
Minor Diego(10) Dia Anthro study Mongol, Anion-
exchange bica->cl; Here Sphero,Cong acan,SE asi
ovalo; can cause HDFN; Cartwri(11) Yta 99.8% Ytb
8%, RBC AcTH; dela HTR, XG(12) Xga → only w/ no
antithe; p-arm X-chro; Adhe CD99 homo; xsignifi
Scianna (13) SC1,2,3; RC-stimu, an-SC3=IgG mild
HTR Dombro(14) Doa/b; Grego/Holl/Josep; xHDN
but mod HTR; Colton(15) CoaCobCo3Coab Trans
prot Cha For Int Pro (CHIP), water channel; kidne,
an-Coa/b → acu to del HTR, Co3 → sev HDN; Chido/
Rodg(17) 2Rod 4WH Ag; HLA; C4a(ro) and C4b(chi)
Chr 6; High Tit, Low Avi (HTLA); complem sys xsig;
Gerbi(20) Ge2,3,4; Wb/Lsa,Ana,DHa; Glycopo C or
D; Leach pheno=Elliptocy; Cromer(21) 7H and 3L,
Decay Acce Fac, Decay of C3/C5 conve; Knop(22)
Kn,Mccoy,Si,Yk york, Chro 1, comple CR1; xHD/TR
Indian(23) two antithe a=low b=high; CD44 adh,
HLA on RBC Bga =B7; Bgb =B17; Bgc =A28 xHD/TRl
↑IM,Leukemia,PCV,HA; RBC and plt have Bga Ag
High inci (public) 99.9; Augu(Ata),Cro(Cra),Enve
(ena),Gerbi(Ge),Gre(Gya),Holle(Hy),Jacob(Jra),Jos
ep(Joa),Lang(Lan),Oka,Vel(Ve) Low Inci(Pri) 1%;
Wright BGS, Swan(Swa), By, Mta, Tra High-Tit,Low
Avid rxn at high dilu, but agg is weak at any dil;
An-chido, An-Yka, An-Rg(rodge), An-Csa (Cost),
An-Kn(knops),An-McC(Mccoy), An-JMH(john milt)
Det of Ab Enzy Enh: Rh,Kidd,P,I,Le; Inac:MNSs,
Duff,Xg,Yt,Chi/Rod Adso,Elution; Neutra: An-p1:
Hydatid flu, Pigeo drop /tur dove egg white, An-
lewis: Secre sal/ser/pla; An-chi/rodg Plas/seru;
An-Sda Gui pig ur; An-I Mom milk; An-H Saliva
Chemi 0.2DTT inac Kell (ex Kx), Kna,Yta,JMH,Hy
ZZAP inac Kell (ex Kx),M,N,Duffy,Yta,Chi/Rg,Pr,Xga
AET inac Kell (ex Kx),Yta,Hy,Kna,Yka,Lub;
Naturally Ocu: Anti-Lewis, Anti-M (rare cause of
HTR/HDN), An-P, An-Lua; Well Developed @ birth
MNSs, Kell, Duffy, Kidd
Discre Gr1: Newborn,Elder,Leuk/lympho hypoga,
Immusup hypoga,Conge agamaglo, Immudef, BM
trans; Reso: RT(15-30m) 40(15-30); Discre Rev; Ab
Gr2: Subgr A/B, Leuke(weak A/B ag), Hodg, Acq B,
Ab to low inci Ag, Exce BGS spe solu subs (BGSS)
carci sto/panc, chimeri; RT/40; BGSS->wash;Forw;
Gr3:↑Globu(MM,Walde,Plas dyscra, adv hodg lym,
↑Fibgen,Plas expan(Dex,PolyviPVP,Wharton; wash
2-3x xplas,wash cord(6-8x) xwhar; Gr4: Polyagg,
Cold reac(Anti-I), Unexpec ABO isoagg (An-H=>A1
/A1B; An-A1=>A2/A2B; Ab other than An-A/B, cis
AB pheno Polyagg Micro: T,Th,Tk,Tx,Acq B, VA;
Non-Mic:Tn Inhe: Cad,Hgb M-hyde,NOR,HEMPAS
/CDA II → Here erybla multi (+) acid ser, Con dyse
ane ty II T Alk-lab tetra,MNSs-sial; neurami:Pnem
cocci,C perf, V cho; expos T ag, m. comm Th weak
neura Proteu, Bacteroi,E.coli,C.aqua Tk Exo/endo
galacto;↓ABH, Ii,P ag; B.frag,C.albi,A.niger,S. marc,
Here/acq; Acq B: mod A to B,Bacte; colon inf, GrA;
E.co O86, P. vulga, Intes ob, Carci colo/rec, GIT inf
Tn Muta lack B3D galac trans, Acq A->P. mira; CAD
↑Sda; HEMPAS i ag CDA tII normo,(+)multinuc,↑i
ag ↓H ag and sialic; NOR P1 Ag M-Hyde expo N-
acetyglu Band 3; Typing Polyagg
autoadsor,Enz,Cord sera (absent),Aged Sera
(absent),Dilu,Adsorp & Elutio
Panel of Lectin: Tn/Cad/T/Tk: Arac hypo --++ Scla
+---, hormi ++--, Gly soja +++-
Lectin: An-A1: Doli biflo (adso anti-A1: GrB ser tre
w/ A2 cells) anti-H: Ulex europe

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