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Meropenem

This document summarizes information about the antibiotic meropenem. It is bactericidal, inhibiting bacterial cell wall synthesis and causing cell death. It is indicated for susceptible intra-abdominal infections, bacterial meningitis in pediatric patients, complicated skin infections, and unlabeled uses including community acquired pneumonia and therapy for febrile neutropenia. Contraindications include allergy to related antibiotics, lactation, and use cautiously with certain conditions. Adverse effects involve the CNS, GI tract, and other issues like superinfections. Nursing considerations include obtaining cultures before use, monitoring for superinfections, and discontinuing for signs of colitis.

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ella joyce
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2K views2 pages

Meropenem

This document summarizes information about the antibiotic meropenem. It is bactericidal, inhibiting bacterial cell wall synthesis and causing cell death. It is indicated for susceptible intra-abdominal infections, bacterial meningitis in pediatric patients, complicated skin infections, and unlabeled uses including community acquired pneumonia and therapy for febrile neutropenia. Contraindications include allergy to related antibiotics, lactation, and use cautiously with certain conditions. Adverse effects involve the CNS, GI tract, and other issues like superinfections. Nursing considerations include obtaining cultures before use, monitoring for superinfections, and discontinuing for signs of colitis.

Uploaded by

ella joyce
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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CLASS

>Antibiotic

ACTION
>Bactericidal: Inhibits synthesis of bacterial cell wall and causes cell death in susceptible cells.

INDICATIONS
>Susceptible intra-abdominal infections caused by viridans group streptococci, E.coli, K. pneumonia, P. aeruginosa, B. fragilis, B. thetaoimicron, and Peptostretococcus >Bacterial meningitis caused by S. pneumoniae, H. influenzae, N. meningitides in pediatric patients 3 mo and older. >Treatment of complicated skin and skin structure infections due to S. aureus, S. pyogenes, S. agalactiae, viridians group streptococci, E. faecalis, P. aeruginosa, E. coli, Peptostreptococcus species >Unlabeled uses: Community acquired pneumonia, therapy for patients with febrile neutropenia

CONTRAINDICATIONS
>Contraindicated with allergy to cephalosporins, penicillins, betalactams; lactation. >Use cautiously with CNS disorders, seizures, renal or hepatic impairment, pregnancy.

ADVERSE EFFECTS
>CNS: Headache, dizziness, lethargy, paresthesias, insomnia >GI: Nausea, vomiting, diarrhea, anorexia, abdominal pain, flatulence, pseudomembranous colitis, liver toxicity >Other: Superinfections, abscess, inflammation at injection site, phlebitis, rash, uticaria, pruritus

NURSING CONSIDERATIONS
>Culture infected area and arrange for sensitivity tests before beginning therapy. >Monitor for superinfections and arrange treatment appropriately. >This drug can only be given IV. >Discontinue drug at any sign of colitis and arrange for appropriate supportive treatment.

GENERIC: >meropenem BRAND: >Merrem IV

GOZUM, ELLA JOYCE A. BSN 4Y1-3 GROUP 632-B

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