Angiogenesis occurs Cancer Cells create new blood vessels that sustain secondary tumor growth
LUNGS
BRAIN
-nagging cough/persistent cough -chest pain -difficulty of breathing -productive cough/ nonproductive cough -crackles/ wheezing sound -presence of dullness on the affected side of the lungs -accumulation of fluid in the lining of the lungs (pleural effusion)
-severe head ache -dizziness -blurring of vision -difficulty in sleeping -problem in maintaining balance -fine motor incoordination ( finger to nose)
V.
PATHOPHYSIOLOGY
Precipitating factors: -environment (pollution) -tobacco use -other carcinogen (asbestos) -occupation (factory worker)
Cellular DNA mutation in tracheobronchial airways
Predisposing factors: -genetic -age (40 above)
Carcinogens binds and damages cells DNA Damage results in cellular changes Abnormal cell growth Malignant Cell DNA is passed on daughter cells Malignant Cells transformed to invasive lung carcinoma
-gender (male)
Malignant Cells will begin to metastasis
Lymphatic System Same process as the bloodstream Stock in the narrow channel of the lymph nodes
Blood Stream
Tumors cancer cell detach and pass through the walls of blood