Numrul total de ore (pe semestru) din

planul de nvmnt
114

FIA DISCIPLINEI
Denumirea disciplinei

INFECTIOUS DISEASES

Tipul de evaluare final (E / V /

C)
Regimul disciplinei (Ob obligatorie, Op opional, F Numrul de
Ob
facultativ)
credite
Total ore din planul de
Total ore de studiu
Total ore pe
75
114
nvmnt
individual
semestru
Anul de studiu VI

Semestrul 1

Titularul disciplinei

E
8
189

PROF.DR.CARMEN MIHAELA DOROBAT

* Dac disciplina are mai multe semestre de studiu, se completeaz cte o fi pentru
fiecare semestru
Total
Facultatea

MEDICINA

Departamentul

MEDICALE 2

Profilul

MEDICINA

Specializarea

MEDICINA GENERALA

C**
114

42

Cunotine minime necesare studenilor pentru parcurgerea noiunilor de curs/stagii/lucrri

practice
Students must know the fundamentals of Biochemistry, Immunology, Medical Microbiology,
Parasitology, Pathophysiology.

Obiectivele disciplinei
1. Knowledge of clinical signs in major infectious diseases.
2. Knowledge of specific therapeutic measures major infectious diseases.
3. Submission of current directions infectious diseases: and re-emerging infectious diseases, antibiotic
therapy.

P
72

Programa analitic a cursului

1. Infectious diseases: general data on infectious pathology.
Etiopathogenesis of infectious diseases
-etiology: presentation of the main infectious agents (bacteria, viruses, fungi)
-pathogenesis of infectious diseases (infectious stages, local and systemic
inflammatory response, MODS).
Diagnostic methods in infectious diseases:
-clinical diagnosis (fever syndrome, eruptive syndrome, other syndromes)
-laboratory diagnosis (bacteriological examinations, serological reactions, idr,
additional tests).
And re-emerging infectious pathology.
2 Principles of treatment in infectious diseases
A.Treatament
-seroterapy
- administration of immunoglobulin-specific
B.Anti- infective treatament.
-the essential characteristics of antibiotics (mechanisms of action,
pharmacokinetics, adverse effects).
-principles of antibiotic;
-main classes of antibiotics (representatives of families of antibiotics, indications,
doses);
-antiviral treatment;
- Antifungal treatment;
C. Treatment pathogenic.
3.Streptococcal infections.
Erizipeloidul Rosenbach.
Measles eruptive diseases. Rubella. Chickenpox. Herpes zoster.
Etiology, clinical manifestations, diagnosis positive, differential diagnosis,
complications, treatment, prevention.
4. Acute respiratory infections. Pertussis. Infectious mononucleosis. Mumps.
Influenza and other viruses respiratorii.Difteria.
Respiratory viruses (other than influenza): etiology, clinical manifestations,
complications, treatment.
Influenza: etiopathogenesis, clinical, laboratory diagnosis, prognosis, treatment,
complications prevention.
Bacterial pneumonia: etiology, clinical manifestations, diagnostic-positive and
differential treatment.
Whooping cough: etiology, clinical manifestations, laboratory tests, clinical forms,
evolution, complications, treatment, prevention.

Nr. ore
3 ore

3ore

3ore

3ore

5. Acute bacterial meningitis.

Viral meningitis.
Tuberculous meningitis.
Fungal meningitis.Acute bacterial meningitis: etiology( according to various
conditions favoring age), pathogenesis, clinical presentation, laboratory diagnosis,
evolution, complications, prognosis, differential diagnosis, principles of
treatment,meningococcal , pneumococcal, H. influnzae, BGN, Listeria, Stafilococ
in nowborn postoperative and posttraumatic meningitis.
Viral menigitis: etiology, clinical presentation, laboratory diagnosis, treatment and
prevention.
Fungal meningitis:etiology, clinicla picture, treatment.
6. Encephalitis.
Polio and other enteroviroze.
Tetanus.
Encephalitis (herpes encephalitis, encephalitis arbovirale, spongiform
encephalopathies): etiology, clinical manifestations, laboratory tests, differential
diagnosis, treatment.
Polio: etiology, clinical diagnosis, treatment.
Tetanus: etiopathogenesis, clinical, laboratory diagnosis, differential diagnosis,
clinical forms, evolution, prognosis, treatment, prevention.
7. Sepsis. Septic shock.
- Definition, Pathogenesis of sepsis, clinical, laboratory diagnosis, and differentialpositive diagnosis, treatment, prevention
8 Infectious diseases digestive input port. (BDA). food Dizenteria.Toxiinfectii
Cholera. Typhoid fever.
Acute diarrheal-disease: etiology, pathogenesis, syndrome of dehydration, treatment
-Dysentery: etiology, clinical complications, differential diagnosis, treatment.
Food-poisoning
-Cholera
-Typhoid: etipatogenie, clinic, laboratory diagnosis, differential diagnosis,
treatment, prevention.
9 ZooantroponozeBotulismul.Trichineloza. Leptospirosis. Brucellosis. Anthrax
Rabies.Lyme.
-Botulism: etipatogenie, clinical manifestations, differential diagnosis, treatment,
prevention.
-Trichinosis: etiology, clinical presentation, laboratory diagnosis, differential
diagnosis, treatment, prevention.
-Leptospirosis: etiopathogenesis, clinical, laboratory diagnosis, differential
diagnosis, treatment, prevention.
- Brucellosis: etiology, clinical complications, laboratory diagnosis, differential
diagnosis, treatment, prevention.
- B. Lyme: etiopathogenesis, clinical, laboratory and differential diagnosis.
-Rabies: etiopathogenesis, clinical, laboratory diagnosis, treatment and prevention.
- Anthrax: etiology, clinical diagnosis, treatment, prevention.

3 ore

3ore

3ore

3ore

3ore

10 .Acute viral hepatitis

hepatitis A: etiology, clinical manifestations, laboratory diagnosis, clinical forms,
differential diagnosis, treatment
Hepatitis B: etiology, clinical presentation, laboratory diagnosis, stages of HBV
infection, clinical forms, prognosis, treatment, prevention.
11 Hepatitis C
Other infections caused by hepatitis viruses
12. Gate skin diseases
Rickettsioze. Malaria. Toxoplasmosis.
-Rabies: etiology, clinical manifestations, laboratory diagnosis, differential
diagnosis, prevention
-Rickettsioze: etiology, clinical manifestations, laboratory diagnosis, clinical
forms, complications, differential diagnosis, treatment, prevention.
-Malaria: etiology, pathogenesis clinical manifestations, laboratory diagnosis,
complications, clinical forms, treatment, prevention.
MODUL HIV/ SIDA 6 ore curs
13. Human immunodeficiency virus infection: etiopathogenesis, clinical and
paraclinical.
14. Human immunodeficiency virus infection /AIDS: diagnostic pozitiv,
stadializare, principii de tratament. positive diagnosis, staging, treatment principles.
Programa analitic lucrri practice/stagii
1 Knowledge of the epidemiological knowledge of clinical and epidemiological
aspects of infectious disease. Medical observation register for patients with
infectious disease.
2. Clinical and paraclinical assessment of the patient with infectious disease
3. Specific data on antibiotic therapy(antibiotics, anti-rabies treatment, antifungal
treatment, etc.
4. Recognizing clinical signs and laboratory in eruptive diseases with airborne
transmission measles, rubella, chicken pox, scarlet . Clinical case presentation
5. Recognition of clinical signs of disease oropharyngeal changes (parodititis,
infectious mononucleosis, infectious stomatitis). 4 ore. Clinical case presentation
(2 h ).
6 . Recognition of clinical and laboratory signs in acute viral hepatitis .4 h. Clinical
case presentation ( 2 ore).
7 .Recognition of clinical and laboratory signs of meningitis cases 4 h. Clinical
case presentation. ( 2 ore).
8. Recognizing clinical signs and laboratory data in acute diarrheal diseases . 4 h.
Clinical case presentation ( 2 h).
9. Sepsis :clinical approach, paraclinical, therapeutic orientation
10. Addressing HIV-positive patient. 6 ore Clinical case presentation. ( 2 h).
11. Biological samples specific infectious diseases
12Collection and delivery of blood to the lab..
13 .Recoltarea, prelevarea si expedierea la laborator a sputei.
14. Harvesting, collection and shipment to the laboratory of sputum.
15. Recoltarea, prelevarea si expedierea la laborator exudatului faringian.
16. Harvesting, collection and shipment to the laboratory of pharyngeal exudate.

3ore

3ore
3ore

3ore
3ore

3ore

8ore
3 ore
4 ore
6ore

6 ore
6 ore
6 ore
6 ore
6ore
2 ore
2 ore
1 ora
1 ora
1 ora
1 ora

17. Harvesting, collection and shipment to the laboratory of pathological

secretions.
18. Prepare patient for lumbar puncture.
19.Therapeutic attitude in infectious shock.

1 ora
2 ore
6 ore

Competene practice dobndite la finalul anului/semestrului

- Clinical skill in recognizing infectious diseases;
- Interpretation of analysis reports hematological, biochemical, bacteriological and serological specific
infectious diseases.
- Guidance in determining treatment of infectious diseases

La stabilirea notei finale se iau n considerare

Ponderea n notare exprimat n

procente
(Total = 100%)

- rspunsurile la examen / colocviu (evaluarea final):

50%

- rspunsurile finale la lucrrile practice de laborator

40%

- testarea periodic prin lucrri de control

- activitile gen teme / referate / eseuri / traduceri /
proiecte etc.
- alte activiti (PRECIZAI) : colocviu

10%

Descriei modalitatea practic de evaluare final E/V (de exemplu: lucrare scris (descriptiv i /
sau test gril i / sau probleme etc.), examinare oral, colocviu individual ori n grup, proiect,
etc.)
Teste scrise semestriale, rspunsuri la lucrrile practice
Examen final: examen practic i test gril unic (60 ntrebri cu rspunsuri multiple)

Estimai timpul total (ore pe semestru) al activitilor de studiu individual pretinse

studentului
(completai cu 0 activitile care nu sunt cerute)
10
1. Descifrarea i studiul notielor de
8. Pregtire prezentri orale
10
curs
10
2. Studiu dup manual, suport de curs
9. Pregtire examinare final
10

3. Studiul bibliografiei minimale

indicate
4. Documentare suplimentar n
bibliotec
5. Activitate specific de pregtire
SEMINAR i / sau LABORATOR
6. Realizare teme, referate, eseuri,
traduceri, etc.
7. Pregtire lucrri de control

10

10. Consultaii

10

10

11. Documentare pe teren

12. Documentare pe Internet

13. Alte activiti ....

14. Alte activiti ....

TOTAL ore studiu individual (pe semestru)

= 75 minimum

Bibliografie obligatorie :
1.

Azoicai D., Manciuc. D.C.Ghid de antibioterapie pentru practica medicala in

Spitalul Clinic de Pneumoftioziologie Iasi, editia a VII-a, Editura Dan, Iasi, 2008
2. Azoicai D., Manciuc. D.C.Ghid de antibioterapie pentru practica medicala in
Spitalul Clinic de Pneumoftioziologie Iasi, editia a VII-a, Editura Dan, Iasi.
3. Dorobat C, Miftode E, Luca M, Leca D, Manciuc C., Mihnea Hurmuzache. Boli
infectioase. Curs pentru studenti si studii postuniversitare. Editura Tehnopress,
2011.
4. Egidia Miftode, V.Luca- Infectious diseases for medicale students. Ed.
Gr.T.PopaIasi, 2002
5. Luca V. , Dorobat C, Dorobat Ghe.-Terapia intensiva in bolile
infectioase.Tehnopress,
Iasi, 2001
6.Vata Andrei, Luca C, Dorobat C.- Boli tropicale. Note de curs. Ed. Gr.T.Popa Iasi,
2012
Bibliografie suplimentar pentru materia de curs i lucrri practice
1.Luca C.-Boli Infectioase pentru studentii la medicina generala.Ed.Tehnopress, 2007,
ed.aII-a
2.Miftode E.- Boli infectioase- Editura Junimea, Iasi, 2008

Data completrii:
2012

Coordonator de activitate didactic.

Prof.Dr. Carmen Dorobat