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PO Vasotec: Generic Name Enalapril Maleate Classification Dosages and Route Trade Name

Enalapril maleate (trade name Vasotec) is an ACE inhibitor used to treat hypertension, heart failure, and left ventricular dysfunction. It works by blocking the conversion of angiotensin I to angiotensin II, decreasing blood pressure. Common side effects include headache, dizziness, fatigue, cough, and GI issues. It is contraindicated in pregnancy and with angiotensin sensitivity. Nursing implications include monitoring for hypotension, avoiding dehydration, and using contraception during treatment.

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732 views2 pages

PO Vasotec: Generic Name Enalapril Maleate Classification Dosages and Route Trade Name

Enalapril maleate (trade name Vasotec) is an ACE inhibitor used to treat hypertension, heart failure, and left ventricular dysfunction. It works by blocking the conversion of angiotensin I to angiotensin II, decreasing blood pressure. Common side effects include headache, dizziness, fatigue, cough, and GI issues. It is contraindicated in pregnancy and with angiotensin sensitivity. Nursing implications include monitoring for hypotension, avoiding dehydration, and using contraception during treatment.

Uploaded by

schnique
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Generic Name Classification Dosages and Route

ENALAPRIL MALEATE PO
Trade Name ACE inhibitor Tablets—2.5, 5, 10, 20
VASOTEC Antihypertensive mg; injection— 1.25
mg/mL

Indications: Contraindications: Nursing Implications:


Oral ● Contraindicated ● Do not stop taking the

with pregnancy, medication without


●Treatment of allergy to enalapril. consulting your health
hypertension alone or in care provider.
com- bination with other ●Use cautiously with
antihypertensives, espe- impaired renal Be careful in any
cially thiazide-type function; salt or ●

diuretics volume depletion situation that may lead


(hypotension may to a drop in blood
●Treatment of acute and occur); lactation. pressure (diarrhea,
chronic heart failure sweating, vomiting,
Adverse Effects: dehydration).● Avoid
●Treatment of over-the-counter
asymptomatic left ● CNS: Headache, medications, especially
ventricular dysfunction dizziness, fatigue, cough, cold, and allergy
(LVD) Parenteral insomnia, medications that may
paresthesias interact with this drug.
●Treatment of
hypertension when oral ●CV: Syncope, chest You may experience
therapy is not possible pain, palpitations, ●

hypo- tension in salt- these side effects: GI up-


Therapeutic Actions: or volume-depleted set, loss of appetite,
Renin, synthesized by patients change in taste
the kidneys, is released perception (will pass
into the circulation ● GI: Gastric with time); mouth sores
where it acts on a irritation, nausea, (frequent mouth care
plasma precursor to vomiting, diarrhea, may help); rash; fast
produce angiotensin I, abdominal pain, heart rate; dizziness,
which is converted by dyspepsia, elevated light-headedness
ACE to angiotensin II, a liver enzymes (usually passes in a few
potent vasoconstrictor days; change position
that also causes release ●GU: Proteinuria, slowly, limit activities to
of aldosterone from the renal insufficiency, those not requiring
adrenals; both of these renal failure, alertness and precision)
actions increase BP. polyuria, oliguria,
urinary frequency, ● Use of contraception is

SCHNIQUE GRANT
Enalapril blocks the impotence advised while taking this
conversion of drug; fetal abnormalities
angiotensin It ●Hematologic: or death may occur.
angiotensin II, Decreased Hct and
decreasing BP, Hgb
decreasing aldosterone
secretion, slightly ●Other: Cough,
increasing serum K+ muscle cramps,
levels, and causing Na+ hyperhidrosis
and fluid loss; increased
prostaglandin synthesis
also may be involved in
the antihypertensive
action. In patients with
heart failure, peripheral
resistance, afterload,
preload, and heart size
are decreased.

Reference:

2012 Lipincott’s Nursing Drug Guide


Amy M. Karch, RN, MS

Nursing Diagnosis Pocket Guide Second Edition


Sheila Sparks Ralph

SCHNIQUE GRANT

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