IAETSD JOURNAL FOR ADVANCED RESEARCH IN APPLIED SCIENCES                                                      ISSN NO: 2394-8442
Ayurceuticals: Recent Development and Future
                                                                Perspectives of Ayurveda
                                                                                                1
                                                                                                    Vinita, 1Morya, G.C.K.,
                                                                                             P.G. Department of Dravyaguna
                                                               L.H.S.P.G. Ayurvedic College and Hospital, Pilibhit (U.P.), India
                                                                                                      gmorya18@gmail.com
   Abstract: Ayurceuticals may be the quite new term for the world of Ayurveda and is a combination of Ayurveda and
   Nutraceuticals. Ayurvedic dietetics and nutrition are novel approach to the world. It evolved with various methods and
   processes as well as nutritional benefits of herbs. Rasayana is the best example of this kind; it nourishes as well as improves
   immunity and keep away from the diseases. So Rasayana preparations are the primitive and broad approach in the field of
   Neutraceuticals. The phytochemicals present in plants are bioactive compound and which are responsible for preventing
   disease and promoting health. In recent years these have been taken much attention in field of health care system. Many
   studies have been still going on for identification and isolation of the chemical components, establishment of their biological
   potency both by in vitro and in vivo studies. Till now study’s findings suggest that phytochemicals may reduce the risk of
   coronary heart disease, detoxify body and neutralize free radicals, the prevention and treatment of diabetes, high blood
   pressure, and macular degeneration. Classical preparations Rasayana have all benefits which are promising today in
   phytochemicals. Present review study aims to highlight the Ayurvedic potential by the name of Ayurceuticals.
   Keywords: Ayurceuticals, Rasayana, Phytochemicals, Neutraceuticals.
                                                  INTRODUCTION
   The term Ayurceuticals suggested that the combination of Ayurveda and Nutraceuticals. It may be the quite new term for
   the world of Ayurveda. As a holistic system of medicine, Ayurveda promotes health, wellness and longevity by its nutritional
   potential such as Rasayana (promoting longevity and vitality), Jeevaniye (promoting vitality), Brihaniye (promoting over
   nutrition), Vayahsthapaniye (promoting longevity) and Balya (promoting strength to the body)1. The fundamental principle of
   nutrition in Ayurveda is based upon the Panchmahabhautika theory, Tridosha siddhanta and Samanya-Visesha siddhanta. These
   three theories constitute the basis of sustenance of life through diet and medicine. Ahara (diet) Nidra (sleep) and Brahmacarya
   (abstinence) are recognized as the three Upasthambhas (sub pillars) essential for the life2. Ahara is considered as the best
   sustainer of life (Annam Vrittikaranam Sreshtam)3 and also Mahabhaisajya4. A balanced diet in Ayurveda is planned in relation
   to the specific known Panchabhautik composition and their Tridoshik impacts in the living body. Acharya Charaka said that
   body is the product of Food and Food is harbinger of happiness and suffering. Food, diet and dietetics have given much
   attention among all classical text. Food sustains the life of all living beings; and complexion, clarity, good voice, longevity,
   genius, happiness, satisfaction, nourishment strength and intellect are all conditioned by the food.
   Ayurveda and Nutrition:
   The Panchmahabhuta theory explains the evolution of microcosm as well macrocosm. Whole universe and its components are
   composed of Panchmahabhuta. Sushruta described that body as well as food are mainly constituted by five Mahabhutas. These
   Mahabhutas have dynamic exchange properties and it is the only way to nourishing as well therapeutic factors for the body.
   All the dietary articles are composed of Panchamahabhutas and their biological derivatives and representatives in the body are
   Tridoshas (Vata, Pitta and Kapha). After consuming the food and their digestion with the help of Jatharagni (digestive fire) and
   then Bhutagni nourishes their respective Panchamahabhutik constituents in the body.
VOLUME 5, ISSUE 1, JAN/2018                                      77                                       http://iaetsdjaras.org/
IAETSD JOURNAL FOR ADVANCED RESEARCH IN APPLIED SCIENCES                                                      ISSN NO: 2394-8442
   A novel concept about Pathya Aahar (wholesome diet- nutrients suitable for an individual are called Pathyas) are delineated
   in Ayurveda. Lolimbaraja said that “If one eats the right kind of food, what is the need of medicine. If one doesn’t eat the
   right kind of food, then no need of medicine”5. There is also a minute attention to the Viruddha aahara (dietary
   compatibilities). There are much more considerations about the diet and nutrition in Ayurveda than other systems.
   Development of Ayurceuticals:
   Ayurvedic dietetics and nutrition are novel approach to the world. It evolved with various methods and processes as well as
   nutritional benefits of herbs. All classical text described the kritanna varga. Food (Ahara) and lifestyle (Vihara) significantly
   affect one’s overall health and the upsurgence of metabolic and degenerative diseases are the result of adaptation of modern
   life style. Most of the incurable diseases are produced due to improper food. Intelligent and self-controlled person should
   consume conductive food in right quantity and at right time to prevent diseases. In this series the concept of Rasayana had
   been evolved to promote longevity and wellness.
   Ayurceuticals and Rasayana:
   The term Ayurceutical is a combination of Ayurveda and Neutraceuticals. Ayurveda described the Anna for nutrition (Rasa
   pradhan) and Ausadha for therapeutics (Virya Pradhan) but it is the physician skills that he can use Anna for therapeutics and
   Ausadh for nutrition. Rasayana is the best example of this kind; it nourishes as well as improves immunity and keep away
   from the diseases. So Rasayana preparations are the primitive and broad approach in the field of Neutraceuticals. The word
   Rasayana is composed of two words Rasa and Ayana. Rasa means Rasa Dhatu (nutritional plasma) and Ayana means pathway
   (microcirculatory channels in the body6. Rasayana is one of the branches of Ashtanga Ayurveda (eight clinical specialities)
   which is not only a drug therapy but is a specialized procedure practiced in the form of rejuvenative recipes, dietary regimen
   and special health promoting conduct and behavior. Rasayana is the way for attaining longevity, memory, intelligence,
   freedom from disorder, youthfulness, excellence of lusture, complexion and voice, optimum level of physical strength and
   sense organs. Rasayana drugs act on work at Dhatu level which reflects its sub-cellular activity. It can be collectively compared
   with antioxidant, regenerative, immuno-modulatory and adaptogenic. Rasayana are not only helps in treating a disease but
   can also be helpful in preventing a disease7
VOLUME 5, ISSUE 1, JAN/2018                                       78                                       http://iaetsdjaras.org/
IAETSD JOURNAL FOR ADVANCED RESEARCH IN APPLIED SCIENCES                                                     ISSN NO: 2394-8442
   Ayurceuticals and Phytochemicals:
                                   Table 1- Bioactive phytochemicals in medicinal plants8
          S.N. Classification              Main groups of compounds             Biological function
                  NSA (Non-starchy         Cellulose, hemicellulose, gums,      Water absorbing capacity, delay
                   Polysaccharides.)       mucilages, pectins, lignins          in nutrient absorption, binding
                                                                                toxins and bile acids
                  Antibacterial &          Terpenoids, alkaloids, phenolics     Inhibits micro-organisms, reduce
                  Antifungal                                                    the risk of fungal infection
                    Antioxidants              Polyphenolic compounds,                free radical quenching, inhibition
                                              flavonoids, carotenoids,               of
                                              tocopherols, ascorbic acid             lipid peroxidation
                    Anticancer                Carotenoids, polyphenols,              Inhibits tumor formation,
                                              curcumine, Flavonoids                  inhibited development of lung
                                                                                     cancer, anti-metastatic activity
                    Detoxifying               Reductive acids, indoles,              Inhibits pro-carcinogen
                    Agents                    tocopherols, phenols, aromatic         activation, inducers of drug
                                              isothiocyanates, coumarins,            binding of carcinogens,
                                              flavones, carotenoids,retinoids,       inhibitors of tumourogenesis
                                              cyanates, phytosterols
                    Others                    Alkaloids, terpenoids, volatile   Neuropharmacological agents,
                                              flavor compounds, biogenic amines anti-oxidants, cancer
                                                                                chemoprevention
                                           Table 2: List of some Rasayana preparations
          Preparations                                 Benefits
          Chyavanprasha                                General health and prevention of respiratory disorders
          Brahma Rasayana                              Protection from mental stress
          Narasimha Rasayana                           Vigor and vitality
          Phala Ghrita                                 Reproductive health
          Arjuna Kshirapaka                            Cardio protection
          Rasona Kshirapaka                            Cardio protection
          Shilajatu Rasayana                           Diabetes mellitus
          Vachadi ghrit                                Improves memory and speech in children
          Brahmi ghrit                                 Improves memory in young and old
                                                      DISCUSSION
   The phytochemicals present in plants are bioactive compound and which are responsible for preventing disease and
   promoting health. In recent years these have been taken much attention in field of health care system. There are many studies
   have been still going on for identification and isolation of the chemical components, establishment of their biological potency
   both by in vitro and in vivo studies. Further more experimental animals, epidemiological and clinical-case control studies in
   man have been also carried on pharmaceutical scale. Till now study findings suggest that phytochemicals may reduce the
   risk of coronary heart disease by preventing the oxidation of low-density lipoprotein (LDL) cholesterol, reducing the
   synthesis or absorption of cholesterol, normalizing blood pressure and clotting and improving arterial elasticity9-10.
   Phytochemicals may detoxify body, neutralize free radicals, inhibit enzymes that activate carcinogens and activate enzymes
   that detoxify carcinogens.
VOLUME 5, ISSUE 1, JAN/2018                                      79                                      http://iaetsdjaras.org/
IAETSD JOURNAL FOR ADVANCED RESEARCH IN APPLIED SCIENCES                                                           ISSN NO: 2394-8442
    Phytochemicals have also been reported for the prevention and treatment of diabetes, high blood pressure, and macular
   degeneration11. Classical preparations Rasayana have all benefits which are promising today in phytochemicals. It is well
   understood that in primitive time technologies was not developed. So our Acharya have concentrated on specialized diseased
   conditions to develop a special Rasayana recipe. Chyawanprash Rasayana for complete wellness, Brahmi Rasayana in mental
   illness and dementia, Shatavari kalpa for galactogogues, Ashagandha for general debility, Shilajatu Rasayana for diabetes, Vyaghri
   haritki awaleha in respiratory disease and many more are in listed.
                                                       CONCLUSION
   Phytochemicals are derived from plants source of and are the secondary bioactive compounds in the medicinal herbs. These
   are unknown in primitive time and only be expressed in the way of active potentials. Extract of medicinal herbs serve as
   secondary metabolites and have been used for many Rasayana preparations since Samhita period. Now gradually development
   in the field of pharmaceuticals and nutraceuticals industries, phytochemicals have been the prime choice and actively used
   in the nutraceuticals products. So it is the high time and need of the hour, that to save our potential of Ayurveda and
   Ayurceuticals. There is an urgent need of attention and requirement for the development of Ayurceuticals.
   http://www.cancer.org/eprise/main/docroot/ETO/c
   Ontent/ETO_5_3X_Phytochemicals, June 2000.
   References
      Shukla, V.D. and Tripathi , R.D. (Eds) 2007, Charak Smhita, (CS.Su.4.19)chaukhamba Sanskrit Pratisthan, Varanasi.
      Shukla, V.D. and Tripathi , R.D. (Eds) 2007, Charak Smhita, (CS.Su.11.35)chaukhamba Sanskrit Pratisthan, Varanasi.
      Shukla, V.D. and Tripathi , R.D. (Eds) 2007, Charak Smhita, (CS.Su.25.40)chaukhamba Sanskrit Pratisthan, Varanasi.
      Pal Satya (Ed.) 2009, Kashyapa Samhita (KS. Kh. 4.6) Chaukhamba Sanskrit Series, Varanasi.
      Tripathi, I.D., Vaidyajiwanam (ed.) Vidyotini Hindi commentary (V.J.1.10) Chaukhamba orientalia, Varanasi (1998)
       Singh,A.K., Gupta, A.K., Manish and Singh, P.K. Rasayana Therapy: A Magic contribution of Ayurveda for healthy long life. Int. J.
       Res. Ayurveda Pharm. 5(1) 2014, 41-47.
      Chaudhari, T.G., Kubde, S., Dive, M. Ayurvedic Approach in Nutraceuticals W.S.R. to Rasayana. Ayushdhara, 2016;4 (2):1135-
       1138.
      Saxena, Mamta & Jyoti, S & Rajeev, N & Dharmendra, S & Abhishek, G. (2013). Phytochemistry of Medicinal Plants. J Pharm
       Phytochem. 1. 168-182.
      Mathai K. Nutrition in the Adult Years. In Krause’s Food, Nutrition, and Diet Therapy, 10th ed., ed. L.K. Mahan and S. Escott-
       Stump, 2000; 271: 274-275
      Ahmad, Akil & Asyikinbinti Abdul Aziz, Zarith & Aishah Mohd Ali, Siti & Mohd-Setapar, Siti. (2016). Application of Herbal
       extract and its medicinal value. Der Pharmacia Lettre. 8. 161-167.
      http://www.cancer.org/eprise/main/docroot/ETO/c
      ontent/ETO_5_3X_Phytochemicals, June 2000.
      http://www.cancer.org/eprise/main/docroot/ETO/content/ETO_5_3X_Phytochemicals, June 2000
VOLUME 5, ISSUE 1, JAN/2018                                         80                                         http://iaetsdjaras.org/