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Nicardipine Hydrochloride

This document summarizes information about the calcium channel blocker nicardipine hydrochloride. It is used to decrease blood pressure in hypertension by inhibiting calcium ion influx into cardiac and vascular smooth muscle cells. Common adverse reactions include headache, dizziness, and edema. It can interact with other antihypertensives, nitrates, beta-blockers, NSAIDs, and grapefruit juice to increase hypotension. Nursing considerations include monitoring for signs of congestive heart failure, fluid status, blood pressure, and adverse drug reactions. The drug is administered via continuous intravenous infusion or oral extended release capsules.

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100% found this document useful (2 votes)
10K views1 page

Nicardipine Hydrochloride

This document summarizes information about the calcium channel blocker nicardipine hydrochloride. It is used to decrease blood pressure in hypertension by inhibiting calcium ion influx into cardiac and vascular smooth muscle cells. Common adverse reactions include headache, dizziness, and edema. It can interact with other antihypertensives, nitrates, beta-blockers, NSAIDs, and grapefruit juice to increase hypotension. Nursing considerations include monitoring for signs of congestive heart failure, fluid status, blood pressure, and adverse drug reactions. The drug is administered via continuous intravenous infusion or oral extended release capsules.

Uploaded by

deo_gratias14
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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DRUG CLASSIFICATION INDICATION MECHANISM OF ACTION ADVERSE REACTION DRUG INTERACTION RATE/FREQUENCY/ DOSAGE NURSING CONSIDERATION

Generic name: Calcium channel Decrease BP in A calcium channel blocker that CNS: headache, dizziness, anxiety, Antihypertensives, nitrates: Side drip of 90cc D5LR 3NaCl  Monitor for CHF;
nicardipine blocker hypertension inhibits calcium ion influx across depression, confusion, increase hypotension + I amp nicardipine @ 50 weight gain, rates,
hydrochloride cardiac and smooth muscle cells paresthesia, somnolence cc/hr parenteral jugular venous
but is more selective to vascular B-andrenergic blockers: distension, dyspnea
smooth muscle than cardiac increase bradycardia, CHF
muscle. Also dilates coronary CV: edema, bradycardia,  Monitor BP and pulse
arteries and arterioles. hypotension, palpitations, NSAID’s: decrease
pulmonary edema, chest pain, antihypertensive effects  Assess surgical pain
tachycardia, increased angina. intensity, location,
Grape fruit juices: increase duration, alleviating
hypotensive effects factors
GI: nausea, vomiting, gastric
upset, constipation, hepatitis, Alcohol: increase hypotension  Monitor potassium,
abdominal cramps, liver function test,
renal studies
periodically
GU: nocturia, polyuria
INTEG: rash  Assess fluid volume
MISC: blurred vision, flushing, status{I & O ratio}&
sweating, shortness of breath records weight

Brand name:
Cardene, Cardene
I.V, Cardene SR

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