Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014
1. Identification of Substance:
 Other means of identification: Catalog Number: DMP900, PDMP900, SMP900
Components: Microplate, Conjugate (contains ProClin 300), Standard (contains ProClin 300), Color Reagent A, Color Reagent B
(contains Tetramethylbenzidine), Assay Diluent (contains ProClin 300), Calibrator Diluent (contains ProClin 300), Wash Buffer
Concentrate (contains ProClin 300), Stop Solution (contains Sulfuric acid).
 GHS product identifier: Human MMP-9 Quantikine ELISA Kit
 Application of the substance / the preparation: For Research Use Only
 Manufacturer/Supplier:
R&D Systems Inc.
614 McKinley Place N.E.
Minneapolis, MN 55413 USA
 For product related questions call: 1-800-343-7475. In Europe call: +44(0)1235-529449.
Emergency information: In case of a chemical emergency, spill, leak, fire, or accident call CHEMTREC at 1-800-424-9300
(US or Canada). Outside USA and Canada: +1 703-527-3887 (collect calls accepted).

2. Hazard Identification:
 Classification: Regulation (EC) No. 1272/2008 [CLP/GHS]
Stop Solution contains Sulfuric Acid: Skin Irrit. Class 2

 Signal Word: WARNING

 Hazard statements: Causes skin irritation and serious eye irritation.
 Precautionary statements: Wash hands thoroughly after handling. Wear protective gloves, clothing and eye and face protection.
Response:
IF ON SKIN (or hair): Immediately remove contaminated clothing and wash before re-use. Wash skin immediately with soap
and water. Get medical attention if irritation persists after washing.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing. If eye irritation persists, get medical attention.
IF SWALLOWED: Call a POISON CENTER or physician if you feel unwell. Rinse mouth.
 Classification according to Directive 67/548/EEC: Irritating to eyes and skin.
 Hazard Symbol / R-Phrase / S-Phrase: Xi, Irritant / R36/38, Irritating to eyes and skin. / S26, In case of contact with eyes, rinse
immediately with plenty of water and see medical advice.
 Other hazards: none

3. Information on Ingredients:
Description: Sulfuric Acid, Formula: H2SO4.
Contains CAS No. EC-No. Index-No. Content
Water 7732-18-5 231-791-2 NA ~90.2%
Sulfuric Acid 7664-93-9 231-639-5 016-020-00-8 ~ 9.8%

4. First Aid Measures:

 IF IN EYES: Rinse thoroughly with water for at least 15 minutes and immediately consult a physician.
 IF ON SKIN (or hair):
Immediately take off contaminated clothing or shoes. Wash with plenty of soap and water. Consult a physician.
 IF INHALED: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
 IF SWALLOWED: Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water.
Immediately consult a physician.
 Potential acute / delayed health effects:
Eye contact: Causes serious eye irritation / causes burns
Skin contact: Causes skin irritation / causes burns
Inhalation: Harmful if inhaled. Exposure to decomposition products may cause a health hazard. Serious effects may be delayed
following exposure.
Ingestion: Harmful if swallowed. Irritating to mouth, throat and stomach. / Causes burns
Rev 3
Page 1 of 11
 Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014
 Notes to physician: Consult a physician. Show this safety data sheet to the doctor in attendance.

5. Fire Fighting Measures:

 Suitable extinguishing agents: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
 Hazards from the substance or mixture: In case of fire, toxic and corrosive gases may be formed.
 Special precautions for fire-fighters: Self contained breathing apparatus and full protective clothing must we worn in case of fire.

6. Accidental Release Measures:

 Person-related safety precautions: Use appropriate personal protective equipment to prevent contamination of skin, eyes and personal
clothing. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.
 Measures for environmental protection: Keep away from drains.
 Measures for containment and cleaning: Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable,
closed containers for disposal.

7. Handling and Storage:

 Precautions for safe handling: Avoid inhalation of vapour or mist. Use normal measures for preventive fire protection.
 Conditions for safe storage: Store in a cool, dry place. Keep container tightly closed in a dry and well-ventilated place. Containers which
are opened must be carefully resealed and kept upright to prevent leakage.

8. Exposure Controls and Personal Protection:

 Control parameters: Contains no substances with occupational exposure limit values
 Appropriate engineering controls: Use with adequate ventilation including local extraction. Ensure that eyewash stations and safety
showers are close to the workstation location.
 Individual protection measures: Wash hands thoroughly after handling chemical products and before eating, smoking or using the toilet.
Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing.
Eye/face protection: Wear approved safety goggles.
Skin/hand protection: Handle with protective gloves, plastic or rubber. Use proper glove removal technique (without touching glove's
outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and
good laboratory practices. Wash and dry hands.
Body protection: Wear suitable protective clothing as protection against splashing or contamination.
Other skin protection: Appropriate footwear and any additional skin protection measures should be selected based on the task being
performed and the risks involved.
Respiratory protection: In case of inadequate ventilation, use a suitable respirator. If the respirator is the sole means of protection,
use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards
such as NIOSH (US) or CEN (EU).

9. Physical and Chemical Properties:

 Appearance: Colorless Liquid Upper/lower flammability or explosive limits: Not available
 Odor: pungent Vapor density : Not available
 Odor threshold: Not available Vapor pressure: Not available
 pH: ~1 Relative density: Not available
 Melting point/freezing point: Not available. Solubility in/Miscibility with Water: Soluble
 Boiling point/Boiling range: Not available Partition coefficient: noctanol/water: Not available
 Flash point: Not available Auto igniting: Not available
 Evaporation rate: Not available Decomposition temperature: Not available
 Flammability (solid, gas): Not available Viscosity: Not available

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 Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014

10. Stability and Reactivity:

 Reactivity: Contact with metals produces highly flammable hydrogen gas. Addition of water liberates excessive heat..
 Chemical Stability: Stable under recommended storage conditions.
 Possibility of hazardous reactions: Under normal conditions of storage and use, hazardous reactions will not occur.
 Conditions to avoid: Bases, Halides, Metals, Alkalis, Acetonitrile.
 Incompatible materials: Most metals, oxidizers, reducers, bases, metal carbonates, cyanides, sulphides, carbides, oxides, metal
acetylides, hydrides, halogens, organic or combustible materials, percholorates, acetonitrile, permanganates, alcohols, picrates.
 Hazardous decomposition products: Products formed under fire conditions: Oxides of Sulphur, Hydrogen gas.

11. Toxicological Information:

 Acute toxicity: Can cause severe burns upon contact while the vapours or mist are corrosive and can cause severe irritation or
damage to the nose, throat and lungs. Ingestion of this product causes pain, nausea and vomiting and may be fatal if large doses
are ingested.
 Skin corrosion/irritation: Can cause severe burns
 Serious eye damage/irritation: Can cause severe burns
 Respiratory or skin sensitization: No data available
 Germ cell mutagenicity: No data available
 Carcinogenicity: No data available
 Reproductive toxicity: No data available
 Specific target organ toxicity (STOT) -single exposure: No data available
 Specific target organ toxicity (STOT) -repeated exposure: No data available
 Aspiration hazard: Can cause severe burns
 Information on likely routes of exposure: Routes of entry anticipated; oral, dermal, inhalation.
 Symptoms related to the physical, chemical and toxicological characteristics:
Inhalation: May be harmful if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory
tract.
Ingestion: May be harmful if swallowed. Causes burns.
Skin contact: May be harmful if absorbed through skin. Causes burns.
Eye contact: Causes eye burns.
 Delayed and immediate effects and also chronic effects from short and long term exposure:
Short term exposure: Potential immediate effects: Not available. Potential delayed effects: Not available.
Long term exposure: Potential immediate effects: Not available. Potential delayed effects: Not available.
 Effects of chronic exposure: Repeated skin contact with this product may lead to dermatitis while repeated inhalation may cause
bronchitis, conjunctivitis, respiratory infections, emphysema and digestive disturbances. May cause erosion and discoloration of the teeth.
 Numerical measures of toxicity: Not available
 Other Information: NA

12. Ecological Information:

 Ecotoxicity: This product may affect the acidity (pH-factor) in water with risk of harmful effects to aquatic organisms.
 Biodegradability: No data available.
 Bioaccumulative potential: No data available.
 Mobility in soil: No data available.
 Other adverse effects: No data available.

13. Disposal Considerations:

 Disposal methods: Dispose of waste in accordance to applicable national, regional, or local regulations.
 Contaminated packaging: Dispose in the same manner as unused product.
 Special precautions: Dispose of small amounts of spilled material as described in section 6. Large spills must be dealt with separately by
qualified disposal personnel. Avoid dispersal of spilt material to soil, waterways, drains and sewers.

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Page 3 of 11
 Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014

14. Transport Information:

 ADR/RID ADN/ADNR IMDG IATA/DOT
ADR/DOT/: UN Number: UN 2796
RID Proper Shipping Name: Sulphuric Acid
Hazard class: 8
Packing group: II

IATA: UN Number: UN 2796

Proper Shipping Name: Sulphuric Acid
Hazard class: 8
Packing group: II

IMDG: UN Number: UN 2796

Proper Shipping Name: Sulphuric Acid
Hazard class: 8
Packing group: II
EmS Number: F-A, S-B
Marine Pollutant: No

15. Regulations:
 US Federal and State Regulations
TSCA (Toxic Substances Control Act): On TSCA Inventory
SARA 313 Components: Not listed
SARA 311/312 Hazards: Acute Health Hazard
CERCLA Reportable Quantity: 1,000 lbs
California Proposition 65: Not listed.

16. Other Information:

 Risk Phrases: R36/38, Irritating to eyes and skin.
 Safety Phrases: S26, In case of contact with eyes, rinse immediately with plenty of water and see medical advice.

 Notice to reader: To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier,
nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final
determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be
used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

2. Hazard Identification:
 Classification: Regulation (EC) No. 1272/2008 [CLP/GHS]
Some components indicated above contain ProClin 300: Skin Sens. 1; H317 – May cause an allergic skin reaction.

 Signal Word: WARNING

 Precautionary statements:
P261: Avoid breathing mist.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear protective gloves.
Response:
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: get medical attention. Wash
contaminated clothing before reuse.

Rev 3
Page 4 of 11
 Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014
 Classification according to Directive 67/548/EEC: The product is classified as a skin sensitizer according to Directive 1999/45/EC and
its amendments.
 Hazard Symbol / R-Phrase / S-Phrase: R43: May cause sensitization by skin contact.
 Other hazards: none

3. Information on Ingredients:
Description: ProClin 300

Contains CAS No. EC-No. Index-No. Content

Modified Alkyl Carboxylate - - - <0.01%
Mixture of 5-Chloro-2- 55965-84-9 - 613-167-00-5 <0.01%
Methyl-4-Isothiazolin-3-
One (26172-55-4) and 2-
Methyl-4-Isothiazolin-3-
One (2682-20-4)
Modified Glycol - - - ≤1.6%

4. First Aid Measures:

 IF IN EYES: Rinse thoroughly with water for at least 15 minutes and immediately consult a physician.
 IF ON SKIN (or hair): Immediately take off contaminated clothing or shoes. Wash with plenty of soap and water. Consult a physician.
 IF INHALED: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
 IF SWALLOWED: Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water.
Immediately consult a physician.

5. Fire Fighting Measures:

 Suitable extinguishing agents: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
 Special precautions for fire-fighters: Self contained breathing apparatus and full protective clothing must we worn in case of fire.

6. Accidental Release Measures:

 Person-related safety precautions: Use appropriate personal protective equipment to prevent contamination of skin, eyes and personal
clothing. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.
 Measures for environmental protection: Keep away from drains.
 Measures for containment and cleaning: Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable,
closed containers for disposal.

7. Handling and Storage:

 Precautions for safe handling: Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Use normal measures for preventive
fire protection.
 Conditions for safe storage: Store in a cool, dry place. Containers which are opened must be carefully resealed and kept upright to
prevent leakage.

8. Exposure Controls and Personal Protection:

 Control parameters: Contains no substances with occupational exposure limit values.
 Individual protection measures: Wash hands thoroughly after handling chemical products and before eating, smoking or using the toilet.
Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing.
Eye/face protection: Wear approved safety goggles.

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Page 5 of 11
 Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014
Skin/hand protection: Handle with protective gloves, plastic or rubber. Use proper glove removal technique (without touching glove's
outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and
good laboratory practices. Wash and dry hands.
Body protection: Wear suitable protective clothing as protection against splashing or contamination.
Other skin protection: Appropriate footwear and any additional skin protection measures should be selected based on the task being
performed and the risks involved.
Respiratory protection: In case of inadequate ventilation, use a suitable respirator. If the respirator is the sole means of protection,
use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards
such as NIOSH (US) or CEN (EU).

9. Physical and Chemical Properties:

 Appearance: Clear Liquid Upper/lower flammability or explosive limits: Not available
 Odor: Not available Vapor density : Not available
 Odor threshold: Not available Vapor pressure: Not available
3
 pH: Not available Relative density: 1.03 g/cm
 Melting point/freezing point: -40º C Solubility in/Miscibility with Water: Soluble
 Boiling point/Boiling range: 189º C Partition coefficient: noctanol/water: Not available
 Flash point: 118º C – closed cup Auto igniting: Not available
 Evaporation rate: Not available Decomposition temperature: Not available
 Flammability (solid, gas): Not available Viscosity: Not available

10. Stability and Reactivity:

 Chemical Stability: Stable under recommended storage conditions.
 Conditions to avoid: Strong oxidizing agents, reducing agents, Amines, Mercaptans
 Hazardous decomposition products: Hazardous decomposition products formed under fire conditions – Carbon oxides, nitrogen oxides
(NOx), Sulphur oxides, Hydrogen chloride gas.

11. Toxicological Information:

 Acute toxicity: LD50 Oral – rat – 862 mg/kg
LD50 Dermal – rabbit- 2800 mg/kg
 Skin corrosion/irritation: Can cause severe burns. Skin – rabbit – Corrosive
 Serious eye damage/irritation: Rabbit – Corrosive to eyes
 Respiratory or skin sensitization: May cause allergic skin reaction.
 Germ cell mutagenicity: No data available
 Carcinogenicity: No data available
 Reproductive toxicity: No data available
 Specific target organ toxicity (STOT) -single exposure: No data available
 Specific target organ toxicity (STOT) -repeated exposure: No data available
 Aspiration hazard: Can cause severe burns.
 Information on likely routes of exposure: Routes of entry anticipated; oral, dermal, inhalation.
 Symptoms related to the physical, chemical and toxicological characteristics:
Inhalation: Harmful if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed. Causes burns.
Skin contact: Harmful if absorbed through skin. Causes burns.
Eye contact: Causes eye burns.
 Delayed and immediate effects and also chronic effects from short and long term exposure:
Short term exposure: Potential immediate effects: Not available. Potential delayed effects: Not available.
Long term exposure: Potential immediate effects: Not available. Potential delayed effects: Allergic contact dermatitis.
 Effects of chronic exposure: ProClin 300 at levels greater than or equal to 0.1% is not identified as probable, possible or a confirmed
human carcinogen by IARC.
 Numerical measures of toxicity: Not available
 Other Information: NA

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Page 6 of 11
 Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014
12. Ecological Information:
 Ecotoxicity: No data available
 Biodegradability: No data available.
 Bioaccumulative potential: No data available.
 Mobility in soil: No data available.
 Other adverse effects: Toxic to aquatic organisms.

13. Disposal Considerations:

 Disposal methods: Dispose of waste in accordance to applicable national, regional, or local regulations.
 Contaminated packaging: Dispose in the same manner as unused product.
 Special precautions: Dispose of small amounts of spilled material as described in section 6. Large spills must be dealt with separately by
qualified disposal personnel. Avoid dispersal of spilled material to soil, waterways, drains and sewers.

14. Transport Information:

 UN Number: None
 DOT regulations: Hazard class: None
 Land transport ADR/RID (cross-border): Not regulated.
 Maritime transport IMDG: Not regulated.
 Marine pollutant: No
 Air transport ICAO-TI and IATA-DGR: Not regulated.
 Transport/Additional information: Not dangerous according to the above specifications.

15. Regulations:
 US Federal and State Regulations
TSCA (Toxic Substances Control Act): On TSCA Inventory
SARA 313 Components: Not listed
SARA 311/312 Hazards: Acute Health Hazard
CERCLA Reportable Quantity: Not listed
California Proposition 65: Not listed.

16. Other Information:

 Hazard Symbol / R-Phrase / S-Phrase: R43 May cause sensitization by skin contact.

 Notice to reader: To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier,
nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final
determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be
used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

2. Hazard Identification:
 Classification: Regulation (EC) No. 1272/2008 [CLP/GHS]
Color Reagent B contains Tetramethylbenzidine in a Proprietary Buffer
Irritant, Dermal – Category 2
Reproductive Toxicity – Category 1B
Acute Toxicity, Dermal – Category 4
Acute Toxicity, Inhalation – Category 4
Eye Irritation – Category 2A
 Signal Word: DANGER
Rev 3
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 Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014

 Hazard statements: H315 Causes skin irritation. H319 Causes serious eye irritation. H312 Harmful in contact with skin. H332 Harmful if
inhaled. H335 May cause respiratory irritation.H360 May damage the unborn child.
 Precautionary statements: P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read
and understood. P261 Avoid breathing fumes. P264 Wash hands thoroughly after handling. P270 Do not eat, drink or smoke
when using this product. P271 Use only in a well-ventilated area. P280 Wear protective gloves and protective clothing. P281
Use personal protective equipment as required.
IF SWALLOWED: Call a poison control center or doctor if you feel unwell.
IF ON SKIN: Wash with plenty of soap and water. Call a poison control center. Wash contaminated clothing before reuse.
IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a poison control center or
doctor/physician if you feel unwell.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF EXPOSED OR CONCERNED: Get medical advice/attention.
 Potential Health Effects:
Inhalation: May be harmful if inhaled. Causes respiratory tract irritation.
Skin: May be harmful if absorbed through skin. Causes skin irritation.
Eyes: Causes eye irritation.
Ingestion: May be harmful if swallowed.

 Classification according to Directive 67/548/EEC: T: Toxic. Repr.Cat.2: Reproductive toxins. Xi: Irritant
 R-Phrase: R61 May cause harm to unborn child, R20/21 Harmful by inhalation and in contact with skin, R36/37/38 Irritating to eyes,
respiratory system and skin.
 S-Phrase: S26 in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 Wear suitable
protective clothing and gloves. S45 In case of accident or if you feel unwell, seek medical advice immediately. S53 Avoid exposure – obtain
special instructions before use.
 Other hazards: Rapidly absorbed through skin.

3. Information on Ingredients:
Description: Tetramethylbenzidine in a Proprietary Buffer

Contains CAS No. EC-No. Index-No. Content

Proprietary Buffer NA NA NA >99%
Tetramethylbenzidine 54827-17-7 259-364-6 NA <0.05%

4. First Aid Measures:

 Consult a physician – Show this MSDS to the doctor in attendance.
 If Inhaled: Move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
 In case of skin contact: Wash off with soap and plenty of water. Consult a physician.
 In case of eye contact: Rinse thoroughly with plenty of water for 15 minutes. Consult a physician.
 If swallowed: DO NOT INDUCE VOMITING. Never give anything by mouth to an unconscious person. Rinse mouth with water. Conult a
physician.
 Most important symptoms and effects, both acute and delayed: To the best of our knowledge, the chemical, physical and toxicological
properties have not been thoroughly investigated.

5. Fire Fighting Measures:

 Suitable extinguishing agents: For small fires, use media such as “alcohol” foam, dry chemical or carbon dioxide. For large fires, apply
water from as far as possible. Use large quantities of water applied as a mist or spray. Solid streams of water may be ineffective. Cool
affected containers with flooding quantities of water.
 Hazards from the substance or mixture: Carbon oxides, Nitrogen oxides(NOx)
 Special precautions for fire-fighters: Self contained breathing apparatus and full protective clothing must we worn in case of fire. Use
water spray to cool unopened containers.

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 Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014
6. Accidental Release Measures:
 Person-related safety precautions: Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.
Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations.
Vapors can accumulate in low areas.
 Measures for environmental protection: Prevent further leakage or spillage if safe to do so. Do not let enter drains.
 Measures for containment and cleaning: Contain spillage, and then collect with non-combustible absorbent material (eg. sand,
diatomaceous earth, vermiculite). Place in a container for disposal according to local regulations.

7. Handling and Storage:

 Precautions for safe handling: Avoid exposure, obtain special instructions before use. Avoid contact with skin and eyes. Avoid inhalation
of vapor and mist. Keep away from origins of ignition. No smoking. Take measures to prevent the build up of electrostatic charge.
 Conditions for safe storage: Store in a cool place. Keep container tightly closed in a dry, well ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.

8. Exposure Controls and Personal Protection:

 Component: Tetramethylbenzidine – Not an occupational hazard at these levels.
 Component: Proprietary buffer
3 3
UK EH40 WEL – Workplace Exposure Limits: Value: STEL, 20 ppm, 61 mg/m . Value: TWA, 10 ppm, 30 mg/m . Can be absorbed
through skin. The assigned substances are those for which there are concerns that dermal absorption will lead to systemic toxicity.

 Appropriate engineering controls: Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after
handling the product.
 Individual protection measures: Wash hands thoroughly after handling chemical products and before eating, smoking or using the toilet.
Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing.
Eye/face protection: Wear approved safety goggles.
Skin/hand protection: Handle with protective gloves, plastic or rubber. Use proper glove removal technique (without touching glove's
outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and
good laboratory practices. Wash and dry hands.
Body protection: Wear suitable protective clothing according to the concentration and amount of the substance at the workplace.
Respiratory protection: In case of inadequate ventilation, use a suitable respirator. If the respirator is the sole means of protection,
use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards
such as NIOSH (US) or CEN (EU).

9. Physical and Chemical Properties:

 Appearance: Liquid Upper/lower flammability or explosive limits: Not available
 Odor: Not available Vapor density : Not available
 Odor threshold: Not available Vapor pressure: Not available
 pH: Not available Relative density: Not available
 Melting point/freezing point: Not available. Boiling point/Boiling range: Not available
 Partition coefficient: noctanol/water: Not available Auto igniting: Not available
 Flash point: Not available Decomposition temperature: Not available
 Water solubility: Not available Viscosity: Not available
 Evaporation rate: Not available
 Flammability (solid, gas): Not available

10. Stability and Reactivity:

 Reactivity: No data available
 Chemical Stability: No data available
 Possibility of hazardous reactions: No data available
 Conditions to avoid: Heat, flames, sparks
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 Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014
 Incompatible materials: Strong oxidizing agents.
 Hazardous decomposition products: No data available

11. Toxicological Information:

 Acute toxicity: no data available
 Skin corrosion/irritation: no data available
 Serious eye damage/irritation: no data available
 Respiratory or skin sensitization: no data available
 Germ cell mutagenicity: Genotoxicity in vitro – mouse – lymphocyte, Mutation in mammalian somatic cells.
 Carcinogenicity: Not classified to its carcinogenicity based on its IARC, ACGIH, NTP or EPA classification at levels less than 0.1%.
 Reproductive toxicity: May cause congenital malformation in the fetus. Presumed human reproductive toxicant.
 Specific target organ toxicity (STOT) -single exposure: No data available
 Specific target organ toxicity (STOT) -repeated exposure: No data available
 Aspiration hazard: No data available
 Information on likely routes of exposure: Routes of entry anticipated; oral, dermal, inhalation.
 Symptoms related to the physical, chemical and toxicological characteristics:
Inhalation: Toxic if inhaled. May cause respiratory tract irritation.
Ingestion: May be harmful if swallowed.
Skin contact: May be harmful if absorbed through skin. May cause skin irritation.
Eye contact: Causes serious eye irritation.
 Delayed and immediate effects and also chronic effects from short and long term exposure: No data available.

12. Ecological Information:

 Ecotoxicity: No data available.
 Biodegradability: No data available.
 Bioaccumulative potential: No data available.
 Mobility in soil: No data available.
 Other adverse effects: No data available.

13. Disposal Considerations:

 Disposal methods: Dispose of waste in accordance to applicable national, regional, or local regulations. Contact a licensed professional
waste disposal service to dispose of this material.
 Contaminated packaging: Dispose in the same manner as unused product.

14. Transport Information:

 UN Number: None
 DOT regulations: Hazard class: None
 Land transport ADR/RID (cross-border): Not regulated.
 Maritime transport IMDG: Not regulated.
 Marine pollutant: No
 Air transport ICAO-TI and IATA-DGR: Not regulated.
 Transport/Additional information: Not dangerous according to the above specifications.

15. Regulations:
 US Federal and State Regulations
TSCA (Toxic Substances Control Act): Proprietary Buffer and Tetramethylbenzidine are listed.
SARA 313: Proprietary Buffer is listed.
SARA 311/312 Hazards: Acute Health Hazard
CERCLA Reportable Quantity: None of the components are listed.

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 Safety Data Sheet

Product Name: Human MMP-9 Quantikine ELISA Kit

Reviewed on: 22 July 2014
California Proposition 65: None of the components are listed on California’s listing of known or potential carcinogens.

16. Other Information:

 R-Phrase: R61 May cause harm to unborn child, R20/21 Harmful by inhalation and in contact with skin, R36/37/38 Irritating to eyes,
respiratory system and skin.
 S-Phrase: S26 in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 Wear suitable
protective clothing and gloves. S45 In case of accident or if you feel unwell, seek medical advice immediately. S53 Avoid exposure – obtain
special instructions before use.

 Notice to reader: To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier,
nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final
determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be
used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

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