BRAND GENERIC NAME MANUFACTURER INDICATIONS CONTRAINDICATIONS SPECIAL PRE Mechanism of Action

NAME CAUTION

ANTIOX Mebendazole Johnson & Treatment of single or Hypersensitivity. Children below 1 yr. Inhibit the synthesis of
Johnson mixed GI worm Pregnancy & old microtubules (Responsible for
infestations by lactation. moving various things in the
roundworm, whipworm, cell like organelles) for and
hookworm, pinworm, destroys already existing ones
threadworm & blocking the uptake of
tapeworm. glucose and other nutrients
resulting in immobilization and
eventual death of helminths.
REXIDOL Paracetamol Inhibits the synthesis of
prostaglandins by inhibiting
the enzyme cyclooxygenase.

Note:
Prostaglandin produces pain
and fever.
LASIX Furosemide Loop diuretic Inhibits
reabsorption of water and
sodium and other ions in the
loop of Henle causing most of
the filtrate (what will be urine)
to remain in the body.

Note:
Loop of Henle is part of the
nephrons (functional unit) in
the kidney where reabsorption
of nutrients and ions take
place.
LORMIDE / Loperamide Slows the intestinal activity by
LORAMIDE HCL blocking calcium channels
and other activities.
BUSCOPAN Hyoscine-N- Sanofi-aventis Acute GI biliary & TAB: Myasthenia Avoid driving and Antispasmodics.
butylbromide genitourinary spasm gravis & megacolon. operating Anticholinergic, causing
including biliary & renal Should not be used in machinery after smooth-muscles to relax
colic. Parenterally also patients who have parenteral through reducing calcium
 as an aid in diagnostic prior sensitivity to administration. mobilization and inhibiting the
& therapeutic hyoscine-N- physiological action of
procedures e.g. butylbromide or any acetylcholine.
gastroduodenal component of
endoscopy, radiology Buscopan. Note:
INJ: untreated Calcium’s role in muscular
narrow-angle contraction is to release
glaucoma, prostate binding sights on actin for
hypertrophy w/ myosin to move actin.
urinary retention, and
mechanical stenosis Acetylcholine is a
in the GIT, neurotransmitter that starts
tachycardia, muscular activity.
megacolon, and
myasthenia gravis.
IM INJ in patients on
anti-coagulants.
Paralytical and
obstructive ileus.
BRICANYL Terbutaline AstraZeneca INJ & TAB: bronchial Hypersensitivity. INJ: Thyrotoxicosis, Terbutaline is a selective Beta
Sulfate asthma, chronic In Obstet: Intrauterine severe CV disorders 2 receptor agonist that
bronchitis, emphysema infection, severe pre- e.g. ischemic heart produces relaxation of smooth
& other diseases of the eclampsia and disease, muscles, specifically in
lungs where ablatioplacentae. tachyarrhythmias or bronchial, vascular and
bronchospasm is a severe heart failure; uterine tissue.
complicating factor. diabetics. Acute
Pre-term labor. severe asthma. Note:
Hypokalemia may Beta 2 adrenergic receptors:
occur. Monitor K Activation of these receptors
levels. Pregnancy & causes the relaxation of
lactation. smooth muscles in the lungs
and dilation of airways.
MIDOL Ibuprofen Menarini Relief of minor aches & Hypersensitivity to Do not take for Relieves pain by inhibiting the
pains associated w/ ibuprofen or aspirin. pain for more than enzyme cyclooxygenase,
menstrual cycle e.g. Allergic reaction e.g. 10 days. CV, renal, white is required for
headache, muscular asthma , swelling, hepatic disease; GI prostaglandin synthesis.
aches, backaches & shock or hives. bleeding or GI
menstrual cramps. bleeding disease.
Do not use during
 pregnancy (3rd
trimester)
NEOZEP 5ML SYRUP: Unilab Inc. Relief of runny nose, Hyperthyroidism, HTN, Glaucoma, Phenylephrine: Alpha 1
 Phenylep nasal congestion, post- coronary & CV cardiac, renal or Adrenergic agonist. Stimulates
hrine HCL nasal drip, itchy & diseases, ventricular hepatic disease; alpha 1 receptors causing
(2.5 mg) watery eyes, fever, arrhythmia, acute- diabetes, asthma; vasoconstriction, increase in
 Chlorphe body pains & narrow glaucoma, alcoholics may blood pressure. Dilated blood
namine headache associated pheochromocytoma impair ability to vessels in the nose can cause
maleate w/ common cold, flu, . MAOI therapy; drive or operate congestion so this causes
(0.5 mg) upper resp. infections, nephropathy machinery. blood vessels to constrict.
 Paraceta allergic rhinitis & sinusitis Pregnancy. (Decongestant)
mol (125
mg) Chlorpheniramine: Treats
ML ORAL DROPS: sneezing, watery eyes and
 Phenylep runny nose caused by
hrine HCl histamines. (Antihistamine)
(1 mg)
 Chlorphe Note:
namine Histamine causes vasodilation,
maleate which then causes sneezing
(0.8 mg) and runny nose.
LIPITOR Atorvastatin Ca Pfizer Total – C  Total Hypersensitivity. Moderate Slows down production of
cholesterol Active liver disease or elevations of serum cholesterol in the body to
LDL – C  Low Density unexplained transaminases; decrease the amount of
Lipoprotein Cholesterol persistent elevations increased risk of cholesterol that may build up
HDL – C  High Density of serum myalgia & on walls on arteris and blood
Lipoprotein Cholesterol transaminases more myopathy in flow by inhibiting HMG-CoA
apo – B  then 3 times the conjunction w/ reductase.
Apolipoprotein B upper limit of normal. increased creatine
TG  Triglycerides Women of phosphokinase Note:
Primary childbearing (CPK) levels more HMG-CoA reductase is a rate
hypercholesterolemia potential. Pregnancy than 10 times ULN in controlling enzyme that
 heterozygous familial & lactation. concomitant w/ produces cholesterol and
& non-familial CYP3A4 inhibitors, other isoprenoids (lipids).
hypercholesterolemia) fibric acid
Hyperlipidemia derivatives, niacin,
Fredrickson type IIA & cyclosporine,
IIB erythromycin, azole
Dysbetalipoprotein  antifungals,
 Fredrickson type IIIA colchicines,
Atherosclerosis  total telaprevir or the
atheroma/plaque vol. combination of
tipranavir/ritonavir.
Patients w.
hemorrhagic
stroke. Increased
HbA1c & fasting
serum glucose
levels. Risk of
hyperglycemia.
BISOLVON Bromhexine HCl An expectorant. Bromhexine
acts on mucus-secreting cell
loosening mucus in the chest
and make it easier to cough
up secretions.
ADALAT Nifedipine Bayer CHD e.g. chronic stable Hypersensitivity. CV Severe Reduces arterial blood
GITS angina pectoris shock. Concomitant hypotension; close pressure reducing peripheral
(angina of effort), HTN use of rifampicin. monitoring of vascular resistance.
Pregnancy & dialysis patients w/ Vasodilator that acts directly
lactation. Patients w/ malignant HTN; on smooth muscles. Works by
Kock pouch heart failure, severe blocking calcium going into
(ileostomy after aortic stenosis. Pre- the muscles in heart and
proctolectomy) existing severe GI blood vessels causing them to
narrowing. Severe relax.
hepatic
impairment.
CHLOROMY Chloramphenic Bacteriostatic that inhibits
CETIN (may ol protein synthesis by inhibiting
be off- bacterial ribosomes.
market) SUSP: Palmitate
INJ: Succinate
AUGMENTIN Co-amoxiclav Infections of upper and Hypersensitivity to B- Renal/hepatc Amoxicillin: Inhibits the
(amoxicillin & lower resp. tract, GUT, lactams e.g. impairment. biosynthesis of cell walls in
clavulanic acid) skin & soft tissue, bone penicillins & Suspected bacteria causing ruptures of
& joint, septic abortion, cephalosporins. infectious the cell membrane. (Beta-
puerperal sepsis, intra- History of Augmentin mononucleosis. lactam antibiotic)
abdominal sepsis, associated Prolonged use,
dental infection, female jaundice/hepatic Pseudomembranou Clavulanic acid: Inhibits the
 genital infections, dysfunction. s colitis. beta-lactamase enzyme of
septicemia, peritonitis & Concomitant use bacteria responsible for the
post-surgical infections; w/ anticoagulants. synthesis of peptidoglycan cell
prophylaxis against Ensure adequate wall in bacteria. Prevents the
infections associated hydration & urinary bacteria from destroying
w/ major surgical output especially amoxicillin.
procedure w/ parenteral
therapy or high
doses. Pregnancy
& lactation.
FLANAX Naproxen Na Taisho Relief of mild to Aspirin or other History of GI disease Analgesic, anti-inflammatory,
moderately severe pain NSAID-induced , edema, Na antipyretic properties. Similar
& fever w/ or w/o asthma, rhinitis or intake, to paracetamol, involves in
accompanying urticaria. Active hematological, inhibition of cyclooxygenase
inflammation e.g. peptic ulcer or GI anaphylactic therefore prostaglandin
musculoskeletal bleeding. Pregnancy reactions, ocular synthesis.
trauma, post-op pain & & lactation. Children effects. Impaired
post dental extraction. below 2 yrs. Old hepatic & renal
Relief of pain function. Do not
associated w. use chronically in
postpartum cramping & patients w/ CrCl
dysmenorrhea. below 20-mL/min.
Treatment of acute Combinations with
migraine attack. NSAIDs/steroids.
May impair ability
to drive or operate
machinery. Elderly.
SOLMUX Carbocisteine Unilab Inc. Relief of cough Peptic ulcer History of gastric or Mucolytic that reduces
associated w/ duodenal ulcer & viscosity of sputum or mucus
excessive & tenacious GI bleeding. and allow to bring up sputum
sputum or phlegm as in Pregnancy & easily.
acute & chronic lactation.
bronchitis, COPD, otitis
media w/ effusion &
glue ear.
CALPOL Paracetamol GSK Consumer Lowering of fever & Hypersensitivity Hepatic or renal Inhibits the synthesis of
Healthcare relief of mild to dysfunction. Do not prostaglandins by inhibiting
moderate pain take more than 4 the enzyme cyclooxygenase.
doses in any 24-hr
 period or more Note:
than 3 days Prostaglandin produces pain
and fever.
ALAXAN Paracetamol, Unilab Inc. Faster relief of mild to Patients in whom Do not use for more Paracetamol: Inhibits the
Ibuprofen moderately severe pain ibuprofen, aspirin & than 10 days for synthesis of prostaglandins by
of musculoskeletal other NSAIDs pain or for more inhibiting the enzyme
origin e.g. muscle pain, precipitate than 3 days for cyclooxygenase.
arthritis, rheumatism, bronchospasm, fever. Peptic ulcer,
sprain, strain, bursitis, angioedema or liver & kidney Ibuprofen: Relieves pain by
tendonitis, backache, nasal polyps. impairment, heart inhibiting the enzyme
stiff neck, tension Advance kidney & failure & high BP> cyclooxygenase, white is
headache, liver diseases. limit alcohol intake. required for prostaglandin
dysmenorrhea, Pregnancy & synthesis.
toothache, pain after lactation.
tooth extraction &
minor surgical
operations. Reduction
of fever.
IBERET- Fe Sulfate, Ca Abbott Treatment & prevention Hypersensitivity. Pernicious anemia. Fe: Important oxygen carrier
FOLIC-500 pantothenate, of Fe-deficiency & Thalassemia, Patients w/ chronic (hemoglobin) and oxygen
folic acid, concomitant folic acid sideroblastic anemia, renal failure & storage (myoglobin)
niacinamide, Vit deficiency w/ associatd hemochromatosis & receiving
B1, Vit B2, Vit B6, deficient intake or hemosiderosis. acetylsalicyclic Folic Acid (Vit B-9): Vital for
Vit B12, Vit C increased need for Vit Children. acid. Hematologic making red blood cells.
B-complex in non- remission may
pregnant adults; vit B- occur while Vit B1 (Thiamine): Essential for
complex deficiencies neurological glucose metabolism. Plays a
manifestations role in nerve, muscle and
remain progressive. heart fxn.
Serum B12 levels
should be regularly Vit B2 (Riboflavin): Essential for
assessed in elderly protein, fat, carbohydrate
& patients w/ metabolism.
condition leading
to Vit B12 depletion. Vit B6 (Pyridoxine): Similar to
Fe therapy could B2, but also help with the
induce relapse of formation of neurotransmitters.
erythropoietic Essential for healthy nervous
protoporphyria system.
 Vit B12 (Cobalamin):
Cooperate with folic acid to
aid the development of red
blood cells.
IMODIUM Loperamide HCl Johnson & Listed in dosage Hypersensitivity. Hepatic Slows the intestinal activity by
Johnson Acute ulcerative dysfunction. blocking calcium channels
colitis or Chronic diarrhea of and other activities.
pseudomembranous unknown etiology.
colitis associated w/ Pregnancy &
broad-spectrum lactation.
antibiotics, primary
therapy in acute
dysentery & when
inhibition of peristalsis
is to be avoided.
Children below 12
yrs. old
ZINNAT Cefuroxime Duncan Lower & upper rep. Hypersensitivity to Hypersensitivity to Bactericidal agent that inhibits
axetil tract, GUT, skim & soft cephalosporins & pencillins & other B- beta lactamase therefore, cell
tissue infections; other B-lactams. lactams. wall synthesis and results in
gonorrhea including Pseudomembranou bacteria death due to lysis.
acute uncomplicated s colitis. Diabetics &
gonococcal urethritis & phenylketonurics. Note:
cervicitis. Early & late Prolonged use. May Lysis: The disintegration of a
Lyme disease in adults impair the ability to cell by rupture of the cell wall
& children above 12 yrs. drive or operate or membrane.
Old. machinery.
Pregnancy &
lactation. TAB:
Jarisch-Herxheimer
reaction.