Scrotal Swelling
`By
  Kasyeba Sowedi
   MBChB-III
                Outline
• Anatomy of the scrotum
• Differential diagnosis
• Approach to a patient with scrotal
  swelling
• Painfull scrotal swelling
• Painless scrotal swelling
  The wall of scrotum has the following
          layers(imp for mcq)
1-skin
2-superficial fascia
3-external spermatic fascia
   derived from the external
   oblique
4-cremasteric muscle derived
   from the internal oblique
5- internal spermatic fascia
   derived from the fascia
   transversalis
6-tunica vaginalis(remnant of
Peritoneum )
• Coverings of the spermatic cord:
  * Tunica vaginalis covers the anterior surface of
  the spermatic cord just above the testis
  * Internal spermatic fascia
  (transversalis/endoabdominal fascia)
  * Cremasteric fascia (fascia of internal oblique
  muscle)
  * External spermatic fascia (aponeurosis of the
  external oblique muscle)
  * The cremasteric fascia contains loops of
  cremasteric muscle, which draws the testis
  superiorly in the scrotum when it is cold.
        Contents of spermatic cord
• Ductus deferens (conveys sperm from the epididymis to the ejaculatory
  duct)
  * Arteries
  * Testicular artery (arises from the abdominal aorta at L2)
  * Artery of the ductus deferens (arises from inferior vesical artery)
  * Cremasteric artery (arises from the inferior epigastric artery)
  * Veins
  * Pampiniform plexus (formed by up to 12 veins, drain into right and left
  testicular veins)
  * Nerves
  * Sympathetic nerve fibers on arteries
  * Sympathetic and parasympathetic nerve fibers on the ductus deferens
  * Genital branch of the genitofemoral nerve supplying the cremaster
  muscle
  * Lymphatics
  * Lymphatic vessels draining the testis and closely associated structures
  * lumbar lymph nodes
               ASSESMENT
We have 3 ways of DDX of scrotal swellings ;
1- acute vs chronic
2- painful vs painless
3- get above it vs can’t
Differential diagnosis of scrotal
            swelling
 APPROACH TO A PATIENT WITH
     SCROTAL SWELLING.
• History
  – timing of onset: acute or insidious onset
  – associated symptoms or prior episodes
  – age at presentation
• Physical examination
  – general appearance
  – lie of testes(to diffrentiate between torsion and epidiymo
    orchitis), scrotal skin, fluid collection,
  – testes or epididymis tenderness
  – Get above the swelling ?
          Investigation:
• Urinalysis: bacteria, WBC’s, crystals
   – commonly in epididymitis
• Obtain urine culture(why ? If pt have +ve
  culture with epidedmytise R/O congenital
  anomaly by US or MCUG (in pediatrics )
• CBC may be helpful
• Radiographic studies
   – Ultrasonography , Nuclear Scan
   – Doppler US.
                            Diagnostic test
                Color Doppler ultrasound
• Noninvasive assessment of
  anatomy and determining
  the presence or absence of
  blood flow.
   – sensitivity: 88.9%
     specificity of 98.8%
   – operator dependent.
                                 FIGURE 1. Color Doppler
                                 ultrasonogram showing acute
                                 torsion affecting the left testis
                                 in a 14-year-old boy who had
                                 acute pain for four hours. Note
                                 decreased blood flow in the left
                                 testis compared with the right
                                 testis
            Color Doppler ultrasound
                                      FIGURE 3. Color Doppler
FIGURE 2. Color Doppler               ultrasonogram showing
ultrasonogram showing late torsion    inflammation (epididymitis) in
affecting the right testis in a 16-   a 16-year-old boy who had
year-old boy who had pain for 24      pain in the left testis for 24
hours. Note increased blood flow
around the right testis but absence   hours. Note increased blood
of flow within the substance of the   flow in and around the left
testis.                               testis.
• Color Dopplar US is imp to differentiate between
  epidedmytis and torsion , the first we will see high
  blood supply in the affected site(infection) while
  in the second decrease blood supply(torsion )
 PAINFUL
 SCROTAL
SWELLING
          1-Testicular torsion(imp)
• It is an Emergency.
• Due to twisting of the testis
  with interference to the arterial
  blood supply.
• May have torsion of cord or
  appendages.
• Incidence is highest between
  10-20 y.o.
                  Clinical Feature
• Testicular pain
  &swelling( Sudden)
  radiating to the lower
  abdomen
• Nausea and vomiting
• previous similar
  episode
• No voiding complaints
• Most cases spontaneous torsion.
• Anterior surface of each testis run towards the
  midline.
                               Types:
 Extravaginal:
  exclusive to
  perinatal (torsion, the
  testis, spermatic cord and
  tunica vaginalis twist en
  bloc) .It is usually
  ASYMPTOMATIC(cuz we
  discover it early before
  appearnce of
  symptoms )...and therefore
  could be managed by
  observation.
                               A) extravaginal; (B)
 Intravaginal: 90%
                                intravaginal
  of adolescent age
  group.
-   extravaginal in        Regarding Rx;
  neonates , and means - In adults we do a
  the whole unit torte .     testicular incision
- Intravaginalis in adults - in children we do
  , means the testes         inguinal incision ? Cuz
  only tort around it self   it’s usually associated
  while the tunica           with hernia
  vaginalis is not
• On Ex:
• Swollen, painful, testis
  drawn up to the groin.
• Absent of cremastic
  reflex on the affected
  site
• Elevation of scrotum
  doesn’t provide relife of
  pain (-ve prehn sign )
• If you in doubt in case of
  acute painful scrotum so
  the scrotum must be
  explored.
• If untreated infarction of
  testis will result.
• Untwisting should be
  carried on within 6 hrs. of
  symptoms.
• The best "test" to
  diagnose torsion is
  SURGICAL
  EXPLORATION once
  suspected
                management
• Rx: EMERGANCY
 Explore the testis.
 Untwist the testis.
 If viable so fix to scrotum
  by anchoring it to scrotal
  septum and if the other
  testis is abnormal fix it.
 If infarcted so remove it.
           2-Torsion of testicular
             appendage(imp):
• Most common structure to twist
  is the appendix of the testis
  (pedunculated hydatid of
  morgagni )
• Usually a more gradual onset,
  pain moderately severe
• Blue dot sign.
• Age:12 – 24 years age .
                                   Blue dot sign.
                            Management
• If dx is in question, surgical
  exploration
Rx ;
- If ur not sure if it’s 1 or 2 do an exploration
  surgery .
- If ur sure Rx conservatively
• immediate operation with ligation
  and amputation of the twisted
  appendage.
• when the appendix torsion is late in
  presentation, it could resemble testicular
  torsion
              3-Testicular trauma
• Usually in sports
  injuries or violance.
• may result in bleeding
  into the layers of tunica
  vaginalis resulting in
  haematocele.
• S&S: severe pain,
  scrotal swelling,
  bruising, tender,
  enlarged testis.
                    Management
• Investigation:
   – scrotal ultrasound (beware of an underlying malignancy).
• Treatment: CONSERVATIVE
   • Bed rest
   • Scrotal elevation
   • Surgical exploration may be needed if:
   1- expanding scrotal hematoma
   2- To evacuate the haematocele and to repair the split in
     tunica albugenea.
   3- very severe pain
  4- Infections of testis & epididymis
• May be acute or chronic.
• Acute or chronic orchitis may be due to mumps.
• Acute epididymo-orchitis may be due to coliform
  organisms or gonorrhoea.
• Also can follow instrumentation or operations on
  prostate.
• Chronic epididymo-orchitis :common cause of is a
  partially treated acute one & TB or brucellosis .
               clinical features :
• pain, edematous, swelling redness of the scrotum,
  often associated with pyrexia.
• +/- symptoms of UTI
• In children differentiation from torsion is often
  impossible and scrotum should be explored.
• Enlarged tender testis and epididymis.
Prehn sign is +ve
Bilatral swelling and pain could be caused by
  lymphoma
                           Management
• Investigation:
   – FBC, MSU, Early morning urine specimens for TB culture.
• Treatment:
      Acute: Bed rest, Analgesia,
      ABx: I.V cipro until culture and sensitivity.
•    Examine the pt in 3 days, if better continue antibiotics, , if pain
    worsens, consider chronic causes
      Chronic: TB-antituberculous drugs.
      Orchidectomy if fails.
      Long ABx treatment for non tuberculous epididymo-orchitis.
 PAINLESS
 SCROTAL
SWELLING
               1- Hydrocele;
• Is collection of abnormal
  quantity of serous fluid in
  the tunica vaginalis.If it
  contains pus or blood it is
  called pyocele or
  haematocele
  respectively.Hydrocele is
  more common than the
  two other varieties.
                             etiology
1-primary;(newborns)
• The cause is unknown
• Associated with patency
  of proccessus vaginalis.
• It is classified as follows;
1-communicating;
it connect with the
   peritoneal cavity.
2-
  noncommunicating;
  it dose not connect
  with peritoneal
  cavity.
2- secondary;  where the fluid
 accumulate secondary to pathology
 inside the testis like epididymo-
 orchitis,testicular tumor and trauma.
infection --- increase production
 +decrease excretion
         Clinical presentation;
 Age;
    primary hyrocele are most common newborns
    Secondary are more common between 20 to 40 years.
 Symptoms;
 1-painless swelling
   2-frequent and painful micturation may occur if hydrocele is
     secondary to epididymo-orchitis
 Hydrocele not affect fertility
                Clinical picture
Examination;
  Position; the swelling usually unilateral but can be bilateral
   .if communicating can not feel the cord above the lump.
  Colour and temperature; normal
  Tenderness; primary are not tender but secondary may be
   tender
  Composition; fluctuant and have fluid thrill if large enough
  Reducibility; can not be reduced
  Testis impalpable(In communicating type) and
   transillumenate
transilluminate
                     Mangement;
Primary; in children
   Communicating;
       most neonatal hydrocele resolve in first 2 year of
        life if persists repair as herniotomy(inguinal
        incision ).
       NEVER do surgery before 2 years of age.(EXCEPT in
1- very large amount -2- if can’t differentiate between it and hernia
3- increase intrabdominal pressure)
       NEVER do needle aspiration EVEN in the non- communicating
    type(cuz it will reaccumulate)
   Noncommunicating;
       usually resolves spontaneously
 In adult; surgical excision; opening the tunica
  vaginalis longitudinally (scrotal incision ), emptying
  the hydrocele, everting the sac after excising the
  redundant sac and suturing the sac behind the cord
  thus obliterating the potential space
 Secondary treatment of the underlying condition
Case ;
40 y old man came with painless , transeluminate hydrocele .
What's ur next step ?
A; do an US for scrotom to R/O testicular tumor
 2- Indirect inguinal hernia:
– most common ( young , Rt. Side )
– 10% bilateral .
– Hernia in babies are a result of persistent processus
  vaginalis.
– If strangulated >> painful and may cause testicular
  atrophy due to ischemia
– Surgery is usually recommended .
3-Varicocele
                       Definition
• Is dilatation and tortuosity of the pampiniform plexus, which
  is the network of veins that drain the testicle.
• Due to defective valve or compression of the vein by a nearby
  structure, can cause dilatation of the veins
• Very common about 20-30% of normal population will have
  some degree of varicocele.
• More common on left side in 98% of cases.
• Bilatral in up to 50% of cases.
• Always remember it’s not painful ..
                                    IMP
Primary varicocele :
is ONLY +ve at standing
 Secondary varicocele : is when varicocele is +ve
   at BOTH standing and supine positions.
Secondary varicocele could be a sign of a retroperitoneal mass
  like Renal Cell Carcinoma, Wilms tumor and
  phaeochromocytoma
-   Do retroperitonial US to role out renal ca in 2 cases ;
1- varicocele on the rt side
2- secondary .
               Clinical feature
1. Appear on standing and disapear on lying down.
2. Heavy or dragging sensation in scrotum.
3. The veins often described as ‘bag of worms’ but
   feeling like a ’plate of lukewarm spaghetti’.
4. The affected testes may be small.
5. 90% of Bilateral varicocele may cause infertility.
6. Be caution that a sudden onset of a left varicocele
   which does not disapear on lying down in old
   patient may be due to an obstruction of left renal
   vein by a renal cell carcinoma.
                  managment
•       Diagnosis:
    –     Clinical and US.
•       Treatment:
        No treatment required in asymptomatic.
        If symptomatic so intervention required either by
         embolization and oblitration under radiological control or
         if surgery indicated varecocelectomy is via inguinal
         approach,all testicular veins being ligated at deep inguinal
         ring.
        In Rx we can do either open or laparoscopic
         varecocelectomy .
4- Epididymal cyst
         Epididymal cyst (spermatocele)
• Cysts arise from
  diverticula of the vasa
  efferentia, they are fluid
  filled cysts connected with
  epididymis.
• May be small ,large
  ,multiple, uni or bilateral.
• Usually occur over 40
  years.
• S&S: Scrotal swelling,
  slowly enlarges, painless.
• Lie above and slightly
  behind the testes.
• You can get above it.
                 Epididymal cyst
• Usually smooth and lobulated, fluctuant,
  transilluminates if contains clear fliud.
• Rx : none unless large or painfull , so surgical
  excision, and that will compromise the fertility of the
  testis.
 5- Idiopathic scrotal edema :
• Difficult to distinguish from torsion/tumor
• Ages 4 to 12
• Sudden onset, unilateral or bilateral but commonly
  bilatral .
• Minimal tenderness
• Normal gonads by U/S Pathognomic sign is thickness
  of scrotal wall on US
• Self limiting process
   – conservative treatment
                 6- Testicular cancer
• The commonest malignancy
  in young men.
• 90% arise from germ cells
  and are either seminomas or
  teratomas.
• 10% are lymphomas, sertoli
  cell tumours or leyding cell
  tumours.
• Imperfectly descended testes
  have a 20-30 The commonest
  malignancy in young men.
                Clinical feature
•  Painless solid swelling of the testis.
•  Heaviness in the scrotum.
•  May be Hx of trauma.
•  Palpable abdominal mass.
•  Spread to para-aortic nodes and to left
  supraclavicular node.
• Chest symptoms due to metastases.
               Investigation
   US to the testis
   CXR
   Tumour markers: AFP, βHCG, LDH
   CT scan
                  treatment
RADICAL INGUNAL ORCHEDICTOMY .
•  If metastasized :
1. If seminoma: Radiotherapy plus chemotherapy.
2. If teratoma: combination chemotherpay 3
   drugs(etoposide, vinblastine, methotrexate,
   bleomycin, cisplastin)