Scrotal swelling
Mogesie Tsegaw
                      Supervised by:
    Dr. Gedion (Assistant professor of general surgery)
    Dr. Kejela (General surgery resident)
                              Outline
 Anatomy of the scrotum and testis
 Differential diagnosis
 Approach to a patient with scrotal swelling
 Painful scrotal swelling
 Painless scrotal swelling
         The wall of scrotum has the following layers
1-skin
2-superficial fascia
3-external spermatic fascia derived from the external oblique
4-cremasteric muscle derived from the internal oblique
5- internal spermatic fascia derived from the fascia transversalis
6-tunica vaginalis (remnant of
Peritoneum )
                            Con’t…
 Coverings of the spermatic cord:
• Tunica vaginalis - covers the anterior surface of the spermatic
  cord just above the testis
• Internal spermatic fascia (transversalis/endoabdominal fascia)
• Cremasteric fascia (fascia of internal oblique muscle)
• External spermatic fascia (aponeurosis of the external oblique
  muscle)
The cremasteric fascia contains loops of cremasteric muscle,
  which draws the testis superiorly in the scrotum when it is cold.
                    Contents of spermatic cord
 Ductus deferens (conveys sperm from the epididymis to the ejaculatory duct)
 Arteries
• Testicular artery (arises from the abdominal aorta at L2)
• Artery of the ductus deferens (arises from inferior vesical artery
• Cremasteric artery (arises from the inferior epigastric artery)
 Veins
• Pampiniform plexus (formed by up to 12 veins, drain into right and left
  testicular veins)
                          Con’t…
 Nerves
• Sympathetic nerve fibers on arteries
• Sympathetic and parasympathetic nerve fibers on the ductus
  deferens
• Genital branch of the genitofemoral nerve supplying the
  cremaster muscle
 Lymphatics
• Testis- to para-aortic LNs
• Scrotum- to superficial inguinal LNs
         Differential diagnosis of scrotal swelling
 ACUTE                           CHRONIC
                                 • Hydrocele
• Testicular torsion
                                 • Varicocele
• Testicular appendage torsion   • Inguinal hernia
• Testicular trauma              • Epididymal cysts
                                 • Spermatocele
• Infection/inflammation         • Testicular tumers
  -epididymi-orchitis
                             Con’t…
Painful                        Painless
  • Torsion of testis or          • Intra-scrotal tumors
   appendages                     • Idiopathic scrotal edema
  • Trauma                        • hydrocele
  • Infection/inflammation        • Varicocele
  • Hernia (strangulation)        • Indirect inguinal hernia
                 Approach to a patient with scrotal swelling
 History
  • timing of onset: acute or insidious onset
  • associated symptoms or prior episodes
  • age at presentation
                              Con’t...
Preparation
• expose from the waist down and the scrotum examined with the
  patient first standing, then supine
• pediatric patients may be best in their carer’s lap.
                               Con’t...
Physical examination
Inspection
• General inspection- noting whether the patient is unwell or in pain.
 Next, assess the inguinoscrotal region for colour, testicular lie, size,
 shape, symmetry, presence of lesions/lumps/oedema/ scars, ‘blue
 dot sign (may become visible only when the skin is stretched)
                              Con’t...
palpation
• Ask the patient about pain before palpating and begin with the
  normal side to allow comparison when examining the abnormal
  side.
• Palpation is easiest in the supine position,
• varicocele/hernia are best appreciated with the patient standing
• Due to testicular mobility, it is recommended to ‘fix’ each testicle
  between both thumbs and index/ middle fingers.
                              Con’t…
• palpate the epididymis (head body and tail).
• Palpate the spermatic cord at the scrotal neck by rolling it
  between thumb and index finger; the vas deferens is appreciated
  as a rubbery, cord-like structure slipping between the fingers.
• Finally, palpate the groin lymph nodes particularly if
  infection/neoplasm are suspected.
                            Con’t…
What to assess on Palpation ?
A) Palpation of the Swelling and appreciate :
• Location, size, shape, surface, warmness, tenderness,
  consistency, Characterise any lumps and determine if they are
  separate from the testis .
• Varicocele is soft, with typical feel of ‘bag of worms’’.
• Hydrocele is smooth and soft
• Testis not felt separately in case of hydrocele
                              Con’t…
B) Get above the swelling:
• In standing position cord is palpated for structures by placing
  thumb in front and fingers behind the root of the scrotum.
• In hydrocele one can get above the swelling – means only cord
  structures are felt and nothing else.
                              Con’t…
• In inguinoscrotal hernia, one can not get above the swelling.
• Cord with additional structures are also felt.
                             Con’t…
C) Check Reducibility
• Inguinal and inguinoscrotal hernia is reducible.
• Hydrocele is not reducible.Exception is congenital hydrocele
  which communicates with abdominal cavity.
• Varicocele gets reduced while lying down but slowly and
  gradually.
                               Con’t…
D) Fluctuation:
• Upper part of the scrotum is held between thumb and fingers of one
  hand to steady the swelling; thumb and fingers of other hand are held
  at lower pole.
• Intermittent pressure from lower fingers will push apart the fingers over
  upper part and vice versa.
• Test is repeated in opposite direction.
• Hydrocele, encysted hydrocele, epididymal cyst, spermatocele, are
  fluctuant swellings in the scrotum.
                           Con’t…
Special tests
 Impulse on coughing
• Hernia shows expansile impulse on coughing.
• Varicocele shows impulse on coughing
                             Con’t…
 Transillumination
• It is done in a dark room using a pen torch.
• Pen torch is placed laterally in the
anterior part of the scrotum.
• Never place it posteriorly as testis
will interfere with proper illumination.
• Hydrocele and epididymal cyst are
• transilluminant
                             Con’t…
 Cremasteric reflex-  is a superficial reflex observed in human
  males.
• elicited by lightly stroking or poking the superior and medial
  (inner) part of the thigh . The normal response is an immediate
  contraction of the cremaster muscle that pulls up
  the testis ipsilaterally.
• may be absent with testicular torsion
                       Investigation
• CBC
• Urinalysis: bacteria, WBC’s, crystals
   commonly in epididymitis
• Radiographic studies
   Ultrasonography(to see haematocele, pyocele, secondary
     hydrocele, varicocele, testicular tumour.
   Doppler US.
   tumor markers: α-fetoprotein, β-human chorionic gonadotropin, and
     lactate dehydrogenase
   • urine culture
PAINLESS SCROTAL SWELLING
                                Hydrocele
• an abnormal collection of serous fluid in a part of the processus vaginalis,
  usually the tunica
Etiopathogenesis- 4 d/t ways
1) Excess fluid production with in the sac
2) Defective fluid absorption
3) Interference with lymphatic drainage
4) Communication with peritoneal cavity
                              Con’t…
Types
1. Congenital- processus vaginalis remains patent or closes defectively
 Defective fluid absorption/Communication with peritoneal cavity.
Includes:
A) Congenital (communicating) or true hydrocele- processus vaginalis
  is patent & communicates with peritoneal cavity.
 Seen in infants
B) Infantile hydrocoele -The sac from the scrotum is patent up to the
  deep inguinal ring.
                           Con’t…
C )Encysted hydrocele - aloculated fluid collection along the
  spermatic cord as a result of aberrant closure of the processus
  vaginalis.
D) Vaginal hydrocoele -Occurs when hydrocoele sac is patent only
  in the scrotum.
E) Funicular hydrocele-has got two communicating sacs, one
  above and one below the neck of scrotum. Upper one lies in the
  inguinal canal.
Con’t…
                                   Con’t…
2. Acquired hydrocoele- either idiopathic (primary) or due to secondary
  causes.
Idiopathic hydrocele- is the most common type of hydrocoele which is
  seen in young adults, middle age and beyond.
It is due to following causes:
a. Defective absorption of fluid
b. Defective lymphatic drainage
                               Con’t…
Secondary hydrocoele- due to underlying conditions such as:
• Infection such as ( filariasis, TB, epididymitis, syphilis)
• Trauma
• Malignancy
• Post-herniorrhapy
Con’t…
                             Con’t…
• inspection-Asymmetrical swelling
• Palpation findings- Fluctuant swelling, not reducible.
 Depending on type of hydrocoele: may or may not be able to get
  above mass. Testis and epididymis may not be definable,
  generally non-tender.
• special tests -Translucent, no cough impulse.
                      Inguinal hernia
• most common ( young , Rt. Side )
• 10% bilateral .
• Hernia in babies are a result of persistent processus vaginalis.
• If strangulated >> painful and may cause testicular atrophy
• Surgery is usually recommended .
                           Con’t…
• Inspection-Unilateral swelling, abdomen may be distended.
• Palpation -May be soft and reducible, or firm and irreducible.
 Unable to get above mass, testis and epididymis definable,
  may be tender (if irreducible/ strangulated, or non-tender).
• special tests -Presence of bowel sounds on auscultation; cough
  impulse may be present.
                          Varicocele
• an abnormal dilatation and enlargement of the scrotal venous
  plexus (pampiniform) draining the testis
• Afecting 10–20% of adult males.
• Mostly idiopathic
• About 90% are left sided, b/c :
 LTV is longer than RTV
 RTV enters right angle to renal vein
 LTA arching over LTV
 Loaded sigmoid colon compressing the LTV
 nutcracker’ effect
                               Con’t…
Note- absence or failure of the antirefux valve an the junction of
 TVs and RVs/IVC could be possible etiology.
• If a left varicocele is identifed, there is a 30–40% probability that it
  is a bilateral condition.
• Typically develop during late childhood and adolescence.
• Varicoceles occur in around 15–20% of all males but are found in
  about 40% of infertile males.
                             Con’t…
Clinical features
• most are asymptomatic,
• dragging discomfort that is worse on standing at the end of the
  day.
• in the erect position, the scrotum on the affected side often hangs
  lower than normal
• Inspection-‘Bag of worms’ may be seen.
• Palpation- Asymmetrical soft swelling, not reducible, bag of
  worms”, testicular atrophy in long standing cases
                               Con’t…
 Able to get above mass, testis and epididymis definable, generally
  non-tender
 lying down the veins empties the veins by gravity and provides an
  opportunity to ensure that the underlying testis is normal to palpation.
• special tests - No transillumination, “, cough impulse may be
  present.
                                Con’t…
• Obstruction of the testicular vein by a renal tumour or nephrectomy
  is a cause of varicocele in later life.
• In such cases the varicocele does not decompress in the supine
  position.
• Isolated right-sided varicocele is extremely rare. But, If patient
  presents, exclude a retroperitoneal mass and deep vein thrombosis
                       Epididymal cysts
• are clear fluid filled cystic degeneration and epididymis
• They are very common, usually multiple and vary in size at
  presentation.
• usually found in middle age and are often bilateral.
• The clusters of tense cysts feel like tiny bunches of grapes that
  lie posterior to, and quite separate from, the testis.
• They should transilluminate. The diagnosis can by confrmed by
  ultrasound
• Testis can be felt separately
                            Con’t…
HX
• Painless scrotal swelling
• Gradual onset
P/E
• get above +ve
• Testis palpable separate from
  the lesion
• Transilluminates
                           Spermatocele
• Unilocular retention cyst derived from a portion of the sperm-
  conducting mechanism of the epididymis.
• It is usually softer and laxer than other cystic lesions in the
  scrotum but, like them, it transilluminates.
• The fluid contains spermatozoa and resembles “barley water in
  appearance”.
• Spermatoceles are usually small. Small spermatoceles can be
Con’t…
                         Testicular cancers
• Most cases of primary testicular cancer are germ cell origin (95%);
  the remainder are stromal (Leydig cell) or sex cord (Sertoli cell)
  tumors.
• Risk factors for testicular tumors include cryptorchidism, family
  history of testicular cancer.
• Testicular malignant neoplasms are the most common tumors in men
  between the ages of 20 and 40 years.
                          Con’t…
• Germ cell–derived tumors- divided into pure seminoma and
  mixed nonseminoma germ cell tumors (NSGCTs) 50% each
• Seminomas – classic seminoma (85%) and spermatocytic
  seminoma.
• NSGCTs can be divided into numerous histologic types:
 embryonal carcinoma,
 yolk sac or endodermal sinus tumors,
 choriocarcinoma,
 teratoma,
 mixed germ cell tumors.
                           Features
• Painless solid swelling of the testis(mostly).
• Heaviness in the scrotum.
• may simulate epididymo-orchitis and, rarely, acute painful
  enlargement of the testis occurs because of hemorrhage into the
  tumour, which can mimic testicular torsion.
• Palpable abdominal mass due to metastasis.
• Chest symptoms due to metastases (shortness of breath, or
  hemoptysis)
PAINFUL SCROTAL SWELLING
                                Testicular torsion
• Is surgical emergency the twisting of the spermatic cord and its
  contents such that the testicular blood supply becomes
  compromised.
• accounts for 10–15% of acute scrotal disease in children.
• Torsion of the testis is uncommon because the normal testis is
  anchored and cannot rotate.
• Testicular torsion is most common between 10 and 25 years of age
                                 Con’t…
Types of torsion
• Extravaginal torsion- outside tunica vaginalis
 seen almost exclusively in neonates due to increased mobility of the
  testicle before the descent into the scrotum ( the lower pole of the
  testis is not yet fixed on the scrotum).
• Intavaginal torsion- inside tunica vaginalis as a result of
high investment of the tunica vaginalis, causing the testis to hang within
  the tunica like a clapper in a bell .
 This is the most common cause in adolescents and is typically a
  bilateral abnormality.
Con’t…
                          Con’t…
Treatment:
Definitive treatment- surgical detorsion
Manual detorsion- medial to lateral, “Opening a book” may
  need to rotate 2-3 times for complete detorsion.
                          Con’t…
precipitating/predisposing factors for torsion
 Cryptorchid testis
 Trauma
 Bell clapper abnormality
 straining at stool,
 lifting of a heavy weight,
 sexual activity and sport
 The two main factors determining damage to the testis ?
 the extent of the twist and the duration of the episode.
                              Con’t…
• Twists of 720° cause more rapid ischaemia than twists of 360° or
  less, and if the testis can be untwisted within 6 hours of the
  torsion taking place there is nearly a 100% chance of testicular
  salvage compared with a 20% salvage rate if the surgery is
  delayed for 24 hours.
                            Con’t…
Hx                                Palpation
sudden severe pain in the groin   • Abnormal lie (horizontal, high),
  and the lower abdomen,            firm and tender testicle
  nausea, vomiting                 able to get above swelling,
P/E                                 testis and epididymis may or
inspection                          may not be definable
Swelling, erythematous or dark    special tests -Absent
  hemiscrotum.                      cremasteric reflex, no
                                    transillumination
             Torsion of a testicular appendage
• cannot always be distinguished with certainty from testicular
  torsion.
• The most common structure to twist is the appendix of the testis
  (the hydatid of Morgagni)
                             Con’t…
Hx
Usually a more gradual onset, pain moderately severe
P/E
• Inspection- ‘’Blue dot sign’’ (due to blood loss to the piece of
  tissue)
• Palpation - Normal lie, soft testicle with pinpoint tenderness.
• special tests - Cremasteric reflex present, no
  transillumination.
                        Testicular trauma
• Usually in sports injuries or violance.
• may result in bleeding into the
layers of tunica vaginalis resulting
 in haematocele.
Clinical features
 severe pain, scrotal
 swelling, bruising, tender,
 enlarged testis.
        Infections of the testis and epididymis
Epididymo-orchitis
• Acute epididymitis most commonly occurs in men aged 20–59
  years (43%) and in men aged 20–39 years and 29% in men aged
  40–59 years).
• Childhood (prepubertal) epididymitis is rare.
• 47% of prepubertal boys with epididymitis have associated
  urogenital abnormalities, including ectopic vas deferens or
  ureters, and urethral abnormalities.
                              Con’t…
• A general rule- epididymitis arises in sexually active young men
  from a sexually transmitted genital infection, while in older men it
  more usually arises from a urinary infection or may be secondary
  to an indwelling urethral catheter.
• In young sexually active men, the most common cause of
  epididymitis is now Chlamydia trachomatis.
• In older men with bladder outflow obstruction, epididymitis may
  result from a urinary infection – it is proposed that a high pressure
  in the prostatic urethra might cause reflux of infected urine up the
  vasa.
                            Con’t…
Clinical features
 ache in the groin
 fever
 epididymis and testis swell and become painful.
 red, oedematous and shiny scrotum, may become adherent to the
  epididymis.
                                Con’t…
Tuberculous epididymo-orchitis
• usually begins insidiously.
• The frequency with which the lower pole of the epididymis is
  involved first indicates that the infection is usually retrograde from
  a tuberculous focus in the seminal vesicles.
                              Con’t…
Clinical features
• firm, discrete swelling of the lower pole of the epididymis.
• epididymis becomes firm and craggy as the disease progress.
• There is a secondary hydrocele in 30% of cases. The seminal
  vesicles feel indurated and swollen. In neglected cases, a
  tuberculous ‘cold’ abscess forms, which may discharge.
• In two-thirds of cases there is evidence of renal tuberculosis or
  previous disease.
Reference
• Bailey & Love's Short Practice of Surgery, 28th Edition
• Schwartz's Principles of Surgery, 11th edition
• Manipal Manual of Surgery 5th Edition
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