Isaac Newton, born on January 4, 1643, overcame a troubled childhood and went on to become a prominent physicist and mathematician, known for his laws of motion and universal gravitation detailed in his 1687 work 'Principia'. He also independently developed calculus, earning a lasting legacy in mathematics and science despite conflicts with contemporaries like Robert Hooke. Newton's later years were marked by his involvement in theology and the Royal Society, and he passed away on March 31, 1727.