IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK) (Q24635274)

1

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M Commane

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Z Jiang

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G R Stark

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

10 April 2001

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published in

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volume

98

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issue

8

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page(s)

4461-5

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cites work

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

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Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

7 April 2017

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

7 April 2017

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The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

7 April 2017

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

7 April 2017

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IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

7 April 2017

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Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein

7 April 2017

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

7 April 2017

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IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

7 April 2017

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A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

7 April 2017

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Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex

7 April 2017

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TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

7 April 2017

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TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

7 April 2017

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Phosphatidylinositol 3-kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement in NFkappaB and AP-1 activation

7 April 2017

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

7 April 2017

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Identification and characterization of an IkappaB kinase

7 April 2017

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TRAF6 is a signal transducer for interleukin-1

7 April 2017

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Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6

7 April 2017

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MyD88, an adapter protein involved in interleukin-1 signaling

7 April 2017

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MyD88: An Adapter That Recruits IRAK to the IL-1 Receptor Complex

7 April 2017

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Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

7 April 2017

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Crossref

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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

22 April 2017

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MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

7 April 2017

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

7 April 2017

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

7 April 2017

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Biologic basis for interleukin-1 in disease

7 April 2017

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Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation

7 April 2017

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Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31857

Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31857

Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

27 September 2017

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Towards an understanding of the signal transduction pathways for interleukin 1.

27 September 2017

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Three NF-kappa B binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression

27 September 2017

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Molecular mechanisms underlying the actions of the pro-inflammatory cytokine interleukin 1. Royal Irish Academy Medal Lecture

27 September 2017

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

27 September 2017

1 reference

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Regulation of human IP-10 gene expression in astrocytoma cells by inflammatory cytokines.

30 May 2018

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Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31857

A critical role for interleukin-1 receptor accessory protein in interleukin-1 signaling

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11287640

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Interleukin-1 Receptor-associated Kinase Is Degraded by Proteasomes following Its Phosphorylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11287640

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.071054198

1 reference

release_gfz4xavthzfythxlc5e6m2form

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gfz4xavthzfythxlc5e6m2form

mapped directly with Wikidata item

24 November 2022

based on heuristic

701027

1 reference

1 reference

701027

PubMed publication ID

11287640

1 reference