Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation. (Q34811265)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9892650%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation (English)

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8 December 2019

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2

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8 December 2019

author name string

C Béraud

series ordinal

1

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8 December 2019

P A Baeuerle

series ordinal

3

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8 December 2019

language of work or name

English

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publication date

1 January 1999

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Proceedings of the National Academy of Sciences of the United States of America

8 December 2019

published in

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8 December 2019

volume

96

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8 December 2019

issue

2

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8 December 2019

page(s)

429-434

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Phosphatidylinositol 3-kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement in NFkappaB and AP-1 activation

8 December 2019

cites work

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

8 July 2018

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IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

8 July 2018

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

8 July 2018

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Phosphoinositide 3-kinases: A conserved family of signal transducers

8 July 2018

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A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

8 July 2018

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Identification and characterization of an IkappaB kinase

8 July 2018

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I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

8 July 2018

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PI3K: downstream AKTion blocks apoptosis

8 July 2018

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Mechanism of activation of protein kinase B by insulin and IGF-1

8 July 2018

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Methodical analysis of protein-nitrocellulose interactions to design a refined digestion protocol

8 July 2018

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

8 July 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

8 July 2018

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NF-kappa B: ten years after

8 July 2018

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8 July 2018

Phosphoinositide kinases

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Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

8 July 2018

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The NF-kappa B and I kappa B proteins: new discoveries and insights

8 July 2018

1 reference

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Structure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Crystal structure of the PI 3-kinase p85 amino-terminal SH2 domain and its phosphopeptide complexes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Phosphatidylinositol 3-kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

8 July 2018

1 reference

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NF-kappa B: a lesson in family values

8 July 2018

1 reference

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Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B

8 July 2018

1 reference

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Rel/NF-kappa B/I kappa B story

8 July 2018

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

8 July 2018

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Correction of radiation sensitivity in ataxia telangiectasia cells by a truncated I kappa B-alpha

8 July 2018

1 reference

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NF-kappa B and rel proteins in innate immunity

8 July 2018

1 reference

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Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

8 July 2018

1 reference

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SH2 domains recognize specific phosphopeptide sequences

8 July 2018

1 reference

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Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

8 July 2018

1 reference

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SH2 domain structure and function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

The inducible transcription activator NF-kappa B: regulation by distinct protein subunits

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Molecular cloning and characterization of a novel Rel/NF-kappa B family member displaying structural and functional homology to NF-kappa B p50/p105.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Tumor necrosis factor alpha mediates a T cell receptor-independent induction of the gene regulatory factor NF-kappa B in T lymphocytes.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.2.429

Sequenching of peptides in a time-of-flight mass spectrometer: evaluation of postsource decay following matrix-assisted laser desorption ionisation (MALDI)

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.2.429

Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15153

Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

26 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.2.429

Transactivation domain 2 (TA2) of p65 NF-kappa B. Similarity to TA1 and phorbol ester-stimulated activity and phosphorylation in intact cells

21 January 2018

1 reference

12 December 2020

N-isopropyliodoacetamide in the reduction and alkylation of proteins: use in microsequence analysis

1 reference

12 December 2020

Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha

1 reference

12 December 2020

Site-specific tyrosine phosphorylation of IkappaBalpha negatively regulates its inducible phosphorylation and degradation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.96.2.429

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9892650%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9892650%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PubMed publication ID

9892650

1 reference