Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination. (Q33952028)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11717399%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

title

Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination (English)

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3 December 2019

1

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3 December 2019

author name string

C Rada

2

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3 December 2019

A M Jones

3

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3 December 2019

C Milstein

4

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3 December 2019

M S Neuberger

5

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3 December 2019

language of work or name

English

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publication date

20 November 2001

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Proceedings of the National Academy of Sciences of the United States of America

3 December 2019

number of pages

6

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based on heuristic

inferred from page(s)

published in

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3 December 2019

volume

98

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3 December 2019

issue

25

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3 December 2019

page(s)

14553-14558

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

3 December 2019

cites work

1 reference

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The Saccharomyces cerevisiae Msh2 mismatch repair protein localizes to recombination intermediates in vivo.

28 July 2018

1 reference

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Steady-state regulation of the human DNA mismatch repair system.

28 July 2018

1 reference

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Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

28 July 2018

1 reference

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The liaison of isotype class switch and mismatch repair: an illegitimate affair

28 July 2018

1 reference

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Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications

28 July 2018

1 reference

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Severe attenuation of the B cell immune response in Msh2-deficient mice

28 July 2018

1 reference

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Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

28 July 2018

1 reference

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Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

28 July 2018

1 reference

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The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

28 July 2018

1 reference

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Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

28 July 2018

1 reference

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Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64720

Ku80 is required for immunoglobulin isotype switching

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64720

Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64720

Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice

28 July 2018

1 reference

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Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64720

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64720

28 July 2018

Antibody class switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64720

A new DNA sequence assembly program

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64720

DNA sequences at immunoglobulin switch region recombination sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64720

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64720

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis

28 July 2018

1 reference

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Nucleotide sequence and properties of the murine γ3 immunoglobulin heavy chain gene switch region: implications for successive Cγgene switching

28 July 2018

1 reference

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Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241525998

Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241525998

Mismatch repair co-opted by hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241525998

PMS2-deficiency diminishes hypermutation of a lambda1 transgene in young but not older mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241525998

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241525998

Developmental and molecular regulation of immunoglobulin class switch recombination.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64720

The many interfaces of Mre11

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11717399

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.241525998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11717399%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

0 references

1 reference

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3 December 2019

PubMed publication ID

11717399

1 reference