Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation. (Q40068992)

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8 January 2020

title

Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation (English)

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8 January 2020

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3

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8 January 2020

Yi-Sheng Cheng

series ordinal

4

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8 January 2020

5

Michael M C Lai

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8 January 2020

2

King-Song Jeng

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8 January 2020

1

Chao-Kuen Lai

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8 January 2020

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language of work or name

English

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publication date

10 October 2007

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8 January 2020

number of pages

15

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based on heuristic

inferred from page(s)

published in

Virology

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8 January 2020

volume

370

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issue

2

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8 January 2020

page(s)

295-309

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

8 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

The product of the ATM gene is a 370-kDa nuclear phosphoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

WebLogo: A Sequence Logo Generator

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Hepatitis C virus infection in patients with non-Hodgkin's lymphoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Effect of alpha interferon on the hepatitis C virus replicon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

The Los Alamos hepatitis C sequence database

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

The C-terminal transmembrane domain of hepatitis C virus (HCV) RNA polymerase is essential for HCV replication in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

ATM binds to beta-adaptin in cytoplasmic vesicles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Hepatitis C virus infection activates the immunologic (type II) isoform of nitric oxide synthase and thereby enhances DNA damage and mutations of cellular genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Hepatitis C Virus Triggers Mitochondrial Permeability Transition with Production of Reactive Oxygen Species, Leading to DNA Damage and STAT3 Activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

DNA damage tumor suppressor genes and genomic instability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Mining viral protease data to extract cleavage knowledge

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Megabase chromatin domains involved in DNA double-strand breaks in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Hepatitis C virus infection is associated with the development of hepatocellular carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Global epidemiology of hepatitis C virus infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

ATM: genome stability, neuronal development, and cancer cross paths

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Establishment of B-cell lymphoma cell lines persistently infected with hepatitis C virus in vivo and in vitro: the apoptotic effects of virus infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Histone H2AX Phosphorylation as a Predictor of Radiosensitivity and Target for Radiotherapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Localization of a portion of extranuclear ATM to peroxisomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037

Nuclear localization of the NS3 protein of hepatitis C virus and factors affecting the localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.08.037