Solute carrier family 30 member 8 (Q7390849)

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mammalian protein found in Homo sapiens

• zinc transporter 8
• solute carrier family 30 (zinc transporter), member 8
• zinc transporter ZnT-8
• SLC30A8

edit

Language	Label	Description	Also known as
English	Solute carrier family 30 member 8	mammalian protein found in Homo sapiens	zinc transporter 8 solute carrier family 30 (zinc transporter), member 8 zinc transporter ZnT-8 SLC30A8

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IWU4

part of

Cation efflux protein, cytoplasmic domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8IWU4

Zinc transporter 8

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8IWU4

Cation efflux transmembrane domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8IWU4

Cation diffusion facilitator

1 reference

Transporter Classification Database ID

2.A.4.3.5

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IWU4

encoded by

SLC30A8

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IWU4

molecular function

protein homodimerization activity

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

cation transmembrane transporter activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

zinc ion binding

determination method or standard

IC

1 reference

retrieved

8 April 2019

stated in

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IC

protein binding

determination method or standard

IPI

3 references

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IPI

retrieved

8 April 2019

stated in

Widespread macromolecular interaction perturbations in human genetic disorders

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IPI

retrieved

8 April 2019

stated in

Exploration of panviral proteome: high-throughput cloning and functional implications in virus-host interactions

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IPI

zinc ion transmembrane transporter activity

determination method or standard

IEA

IDA

TAS

3 references

retrieved

16 July 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

TAS

retrieved

16 July 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

16 July 2018

stated in

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

IDA

zinc ion transmembrane transporter activity

determination method or standard

IBA

IDA

IEA

TAS

4 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IBA

cell component

integral component of membrane

determination method or standard

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IWU4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

Golgi apparatus

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IDA

secretory granule membrane

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

TAS

membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IWU4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

plasma membrane

determination method or standard

IDA

IEA

2 references

retrieved

16 July 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IWU4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

16 July 2018

stated in

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

IDA

transport vesicle membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IWU4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

secretory granule

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IDA

cytoplasmic vesicle

determination method or standard

IEA

ISS

3 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IWU4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

plasma membrane

determination method or standard

IBA

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IWU4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IBA

biological process

response to interleukin-1

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

response to interferon-gamma

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

glucose homeostasis

determination method or standard

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

ISS

regulation of vesicle-mediated transport

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

zinc ion transport

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IWU4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IDA

response to zinc ion

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IBA

cation transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

insulin secretion

determination method or standard

IEA

IMP

2 references

retrieved

16 July 2018

stated in

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

IMP

retrieved

16 July 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

ion transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IWU4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

response to glucose

determination method or standard

IEA

IMP

2 references

retrieved

16 July 2018

stated in

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

IMP

retrieved

16 July 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

cation transmembrane transport

determination method or standard

IEA

1 reference

retrieved

16 July 2018

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

sequestering of zinc ion

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IDA

cellular zinc ion homeostasis

determination method or standard

ISS

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

regulation of sequestering of zinc ion

determination method or standard

IBA

ISS

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IBA

positive regulation of insulin secretion

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

zinc ion transmembrane transport

determination method or standard

IEA

1 reference

retrieved

16 July 2018

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWU4&geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

transmembrane transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

response to glucose

determination method or standard

IBA

IEA

IMP

3 references

retrieved

8 April 2019

stated in

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IMP

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IBA

insulin secretion

determination method or standard

IBA

IEA

IMP

3 references

retrieved

8 April 2019

stated in

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IMP

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IBA

zinc ion transmembrane transport

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWU4

determination method or standard

IBA

Gene Atlas image

PBB GE SLC30A8 gnf1h06210 at fs.png
732 × 530; 10 KB

0 references

Identifiers

RefSeq protein ID

NP_001166282

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

169026

NP_001166284

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

169026

NP_001166285

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

169026

NP_001166286

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

169026

NP_776250

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

169026

XP_024302851

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

169026

UniProt protein ID

Q8IWU4

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IWU4

Ensembl protein ID

ENSP00000407505

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000407505

ENSP00000415011

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000415011

ENSP00000428545

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000428545

ENSP00000431069

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000431069

ENSP00000427760

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000427760

ENSP00000485167

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000485167

ENSP00000485566

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000485566

Transporter Classification Database ID

2.A.4.3.5

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

 

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q7390849&oldid=2022910136"