Its findings are based on information received from local authorities.
Up to 70 percent of nurses could resign in several specialist hospitals. Urgent tests and care will be reduced or specifically impaired in all hospital districts where mass resignations take place.
The Ministry emphasizes that necessary staff transfers could not be implemented in all emergency situations as specialist training was so often required.
On the basis of received data, the Ministry adds that mass resignations would endanger patients' health and lives.
The Ministry has invited representatives of the Nurses Union Tehy for talks on Thursday to discuss patient safety.
Talks Continue in Nurses Dispute
Both sides met for another round of negotiations for a deal on pay and conditions at the office of National Conciliator Juhani Salonius on Wednesday.
Salonius said both sides remained far apart, noting that any move was possible: they might reach a deal or the industrial action would take place.
The Commission for Local Authority Employees is to challenge the legality of threatened industrial action in a labour tribunal. Employers believe the mass resignations are illegal and break a strike ban. They want the tribunal to impose fines on the union.
Tehy began a boycott on open job positions on Monday. If negotiations fail to bring results, almost 13,000 nurses will stage a mass resignation starting November 19.
