Rachel Spilo
ColoradoBiz Staff //July 30, 2025//
Rachel Spilo is a trailblazing entrepreneur whose vision and leadership have reshaped the U.S. healthcare landscape. As the founder and CEO of Catalyst Solutions, Rachel has spent more than 26 years growing the company into a nationally respected provider of business process outsourcing and strategic solutions for some of the country’s largest health insurers. Her leadership has guided Catalyst to consistent growth and recognition, earning spots on the Inc. 5000 Fastest-Growing Companies list and honors such as the SBA’s Entrepreneur of the Year award.
Never one to stand still, Rachel demonstrated bold foresight in 2024 when she identified artificial intelligence as both a threat and an opportunity for the healthcare industry. Acting on her vision, she launched Healthplans.ai and now serves as its founder and chairman of the board. This innovative company uses advanced AI to automate and streamline complex processes for health insurers nationwide, setting a new standard for operational efficiency and demonstrating Rachel’s commitment to staying ahead of industry shifts.
Rachel’s journey from her working-class roots to leading companies valued in the hundreds of millions inspires everyone around her. She founded her first business at age 20 without a college degree or financial safety net and has since become a model of resilience, humility and fearless execution.
Her dedication to community impact shines through The Impact of One, a nonprofit she founded to prove that even small actions can create lasting change. The organization has brought clean water, education and vital services to communities around the globe.