Discoveries Scratching Beneath the Surface: Cryo-EM Guides New Opioid Drug Design Cryo-EM revealed the molecular basis of KOR signaling bias, enabling structure-based drug design of an anti-pruritic peptide with reduced side effects. #structural-biology #cryosparc #cryo-em CryoSPARC Team · June 16, 2026
Case Studies A Complex Story: A Case Study in Cryo-EM Heterogeneity From active and deactive states to additional respiratory complexes, this case study shows how a single cryo-EM dataset can tell many different stories when viewed through the lens of heterogeneity. #structural-biology #cryosparc #cryo-em CryoSPARC Team · June 9, 2026
Discoveries A New Step in the Fight Against Measles How Cryo-EM allows a closer look at the Human neutralizing antibodies targeting the measles virus #structural-biology #cryosparc #discoveries CryoSPARC Team · June 5, 2026
Small Protein Targets The Resolution Revolution Is Still Ongoing High-Resolution Ab-Initio Reconstruction: Extending Cryo-EM to Smaller Particles with CryoSPARC™ #structural-biology #cryosparc #cryo-em CryoSPARC Team · May 27, 2026
CryoSPARC Updates CryoSPARC v5.0 stable release Explore the new features, expanded capabilities, and a more intuitive processing experience! #structural-biology #cryosparc #release CryoSPARC Team · May 27, 2026