BIOS
AI Scientist for biomedical research - #1 on BixBench
SubscriptionAIWorkflow automation2,128 impressions#17 of its week
BIOS is an AI Scientist that designs, builds, and validates therapeutic peptide binders from a single prompt.
- for
- Biomedical researchers and drug discovery teams seeking AI-driven design and lab automation.
- pricing
- freemium
Key features
- Literature Agent — Plans research questions, searches papers, patents and databases, and returns a cited answer.
- Binder Generation — Three generative models propose candidates and six orthogonal filters shortlist the most promising designs.
- Autonomous Lab — A synthesis box and robotic arm synthesize top designs and assay them on live cells, feeding results back to the model.
- CLI Workspace — Full command-line interface for running design, analysis, and workflow commands from the terminal.
- Human-in-the-Loop — Allows users to intervene at checkpoints or run fully autonomous pipelines.
- Open Model Stack — Runs open models such as RFdiffusion3, BoltzGen, PXDesign, RFdiffusion3, Boltz-2, ESMFold2, mmseqs2 and Foldseek.
Use cases
- Design a therapeutic peptide binder for a target receptor in under an hour.
- Run a literature-driven research project that returns a cited answer and next experiment suggestions.
- Automate the synthesis and cell-based assay of top-ranked peptide candidates.
- Integrate AI-driven design into existing bioinformatics pipelines via the CLI.
BIOS vs alternatives
| Best for | AI-guided peptide binder design | No-code workflow automation | App integration automation | Open-source no-code automation | Universal sandbox for AI agents |
|---|---|---|---|---|---|
| Pricing | Freemium | Subscription | Subscription | Free | Free |
| DevHunt upvotes | 0 | 0 | 0 | 0 | 73 |
| Launched | Feb 2026 | — | — | — | Apr 2026 |
- BIOS vs n8n: General workflow automation platform, not specialized for biomedical AI design.
- BIOS vs Zapier: Automation across apps, lacks AI-driven binder design and lab hardware.
- BIOS vs Activepieces: Open-source automation, focuses on generic tasks rather than drug discovery pipelines.
- BIOS vs Pocketenv: Provides a sandbox runtime for agents, but does not include the specialized biology models and hardware loop.
BIOS FAQ
What does BIOS do?+
BIOS reads the literature, designs candidate protein binders with AI models, filters them, and helps take the top designs into an autonomous lab for synthesis and testing.
How are binders generated and filtered?+
Three generative models (RFdiffusion3, BoltzGen, PXDesign) propose candidates, then six orthogonal filters (structural, agreement, physics, selectivity, dynamics, developability) reduce ~100 designs to ~10 promising ones.
How long does a design run take and what does it cost?+
A typical run produces a shortlist of ten designs in about 35 minutes and costs roughly $8 of compute.
Can BIOS be used as a literature research agent?+
Yes, BIOS can plan a research question, search papers, patents and databases, run analyses, and return a cited answer with suggested next steps.
How do I start using BIOS?+
You can chat with BIOS at chat.bio.xyz or install the CLI with a single script; academic users with a .edu address get full free access.
Summarized by DevHunt from ai.bio.xyz · Oct 8, 2026. Details may change; check the official site.