Scientific rationale for study The literature about lasers in the field of periodontology is contradictory. The present study aimed at evaluating benefits of Er, Cr: YSGG laser irradiation following deep scaling compared to scaling alone in a randomized controlled clinical trial based on an appropriate sample size. Principal Findings The present study demonstrated that laser irradiation combined with conventional Sc/RP did not improve the clinical outcomes regarding probing pocket depth reduction and attachment level gain compared to Sc/RP alone. Practical implications Taken into account that lasers are expensive devices and no superior results can be expected by using them, their recommendation for clinical application is still questionable.
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