View source for LIRYC

{{Infobox organization
|name           = LIRYC - Electrophysiology and Heart Modeling Institute
|image          = IHU-Liryc-bordeaux-english.jpg
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|formation      = 2011
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|purpose        = Research : [[Cardiology]], [[Electrophysiology]], [[Medical imaging|Imaging]], [[3D modeling|modeling]]
|headquarters   =
|location       = Pessac, France
|coords         = {{Coord|44.797383|-0.660471|type:landmark|display=inline,title}}
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|language       = French, English
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|parent_organization = [[University of Bordeaux]]
|affiliations   = [[University of Bordeaux]], University Hospital of Bordeaux, [[CNRS]], [[INSERM]], [[INRIA]], Région Aquitaine
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|website        = [http://www.ihu-liryc.fr/ www.ihu-liryc.fr]
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{{Location map | France
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| label    = Pessac
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| caption = Location of LIRYC in France
| lat_deg =  44.797383
| lon_deg = -0.660471
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The '''Electrophysiology and Heart Modeling Institute''' (''French: '''L'I'''nstitut de '''RY'''thmologie et Modélisation '''C'''ardiaque''), is one of six French university hospital institutions created in 2011 as part of the Investments for the Future program (''Investissements d'avenir''<ref>[http://www.accelence.org/2012/03/the-bordeaux-university-hospital-and-the-investments-for-the-future-program/ The Bordeaux University Hospital and the "Investments for the Future" program]</ref>) to boost medical research and innovation.

This institute, headed by [https://www.ihu-liryc.fr/fr/professeur-pierre-jais/ Professor Pierre Jaïs] along with [[Michel Haïssaguerre|Professor Michel Haissaguerre]], Dr [https://www.ihu-liryc.fr/fr/docteur-meleze-hocini/ Mélèze Hocini] and the cardiology teams of the University Hospital of Bordeaux, unites multiple specialties around cardiac [[electrophysiology]] from research on [[ionic channel]]s (microgenerators producing electric flows in cells) to  whole heart and patient care.

== Institute presentation ==
LIRYC<ref>[http://www.labex-univ-bordeaux.fr/en/LabEx/Direct-Access/Downloads/Flyer-LYRIC-Electrophysiology-and-Heart-Modeling-Institute,i355.html Flyer - Electrophysiology and Heart Modeling Institute LIRYC]</ref> is a basic research, clinical and teaching centre  focusing on the understanding, care and treatment of [[Cardiac dysrhythmia|cardiac electrical diseases]]  that lead to [[heart failure]] and [[Sudden cardiac death|sudden death]].{{cn|date=March 2024}}

It includes national and international doctors and researchers in [[cardiology]], [[Medical imaging|imaging]] and [[signal processing]] and [[3D modeling|modeling]], who have overlapping interests and skills in cardiac bio-electricity.{{cn|date=March 2024}}

== Research fields ==
[[Cardiovascular disease]] is the primary cause of mortality in the world,<ref>[https://www.who.int/mediacentre/factsheets/fs317/en/ World Health Organization Report March 2013]</ref> accounting for 30% of deaths, followed by communicable, maternal, neonatal and nutrition conditions (23%)<ref>[https://web.archive.org/web/20070314013115/http://www.who.int/mediacentre/factsheets/fs310/en/index2.html World Health Organization]</ref> and [[cancer]] (13%).<ref>[https://www.who.int/mediacentre/factsheets/fs297/en/ World Health Organization Report February 2014]</ref>

Cardiac electrical diseases are responsible for more than 700,000 deaths each year in Europe.
[[File:Afib ecg.jpg|thumb|left|baseline|upright=1.1|link= |alt=Afib ecg|Atrial fibrillation ECG]]
* Half of these deaths come from [[heart failure]] which often develops from electrical heart rhythm problems such as [[Cardiac dysrhythmia#classification|atrial fibrillation]].

[[File:Ventricular fibrillation.png|thumb|left|middle|upright=1.1|link= |alt=|Ventricular fibrillation ECG]]
* The other half of these deaths occur suddenly due to an extreme and instantly fatal cardiac turbulence called [[ventricular fibrillation]], which can be compared to an electric "tornado". (The term "[[cardiac arrest]]" is often confused with "[[Sudden cardiac death|sudden death]]" from [[ventricular fibrillation]].) This sudden death rate is equal to the combined deaths from [[breast cancer|breast]], [[lung cancer|lung]], and [[colo-rectal cancer|colon]] cancer<ref>[https://www.who.int/mediacentre/factsheets/fs297/en/index.html The World Health Report 2008 - Cancers]</ref> and [[AIDS]].<ref>{{cite news|title=AIDS Epidemic Update 2009 |publisher=ONUSIDA-OMS |date=December 2009  |url=http://www.theheart.org/fr/article/1062845.do}}</ref>

LIRYC focuses on cardiac electrical diseases responsible for mortality or severe disability ([[embolic stroke]]). It utilizes a multidisciplinary approach which combines several fields such as high resolution [[Optical mapping|mapping]], [[Medical imaging|cardiac imaging]], and [[signal processing]] and cardiac [[Model (person)|modeling]].

== Partnerships ==
Partners include academic teams from research institutions such as [[INSERM]], [[CNRS]], [[INRIA]], the [[University of Bordeaux]], and the University Hospital of Bordeaux, as well as health care industry partners.{{Citation needed|date=August 2022}}

== Facilities ==
Research teams currently work at the Technological Platform for Biomedical Innovation (''French: Plateforme technologique d'innovation biomédicale - PTIB'')",<ref>[http://www.ptib.u-bordeaux2.fr/index.php?p=accueil PTIB : Plateforme Technologique d'Innovation Biomédicale]</ref> which is located at the [[Xavier Arnozan]] Hospital in [[Pessac]].{{cn|date=March 2024}}

By 2015, a 6,000 square meter extension of the existing PTIB building will be built. It will house a platform for medical research and innovation, combining facilities and competencies in [[electrophysiology]] (''[[optical mapping]]''), [[interventional cardiology]], [[Medical imaging|cardiac imaging]] (high resolution [[Magnetic resonance imaging|MRI]] 9.4 Tesla), [[3D modeling|modeling]] and [[signal processing]]. It will also provide a training centre for students, engineers and researchers in collaboration with the main health care companies.{{cn|date=March 2024}}

== See also ==
* [[University of Bordeaux]]
* [[INSERM]] - National Institute of Health and Medical Research
* [[CNRS]] - French National Centre for Scientific Research
* [[INRIA]] - National Institute for Research in Computer Science and Control

== References ==
{{reflist}}

== External links ==
* [http://www.ihu-liryc.fr/ Official website of LIRYC]
* [https://www.who.int/mediacentre/factsheets/fs317/en/index.html World Health Organization - Cardiovascular diseases]

[[Category:2011 establishments in France]]
[[Category:Medical and health organizations based in France]]