Hydroxyestrone diacetate

Hydroxyestrone diacetate
Clinical data
Trade names	Colpoginon, Colpormon, Hormobion, Hormocervix
Other names	RD-310; 16α-Hydroxyestrone diacetate; 3,16α-Dihydroxyestra-1,3,5(10)-trien-17-one 3,16α-diacetate
Routes of; administration	By mouth
Drug class	Estrogen; Estrogen ester
Identifiers
	IUPAC name [(8R,9S,13S,14S,16R)-3-acetyloxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-16-yl] acetate;
CAS Number	1247-71-8;
PubChem CID	102046;
ChemSpider	92184;
UNII	2U3VOE52DG;
CompTox Dashboard (EPA)	DTXSID50878610 ;
ECHA InfoCard	100.013.634
Chemical and physical data
Formula	C22H26O5
Molar mass	370.445 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)OC1CC2C3CCC4=C(C3CCC2(C1=O)C)C=CC(=C4)OC(=O)C;
	InChI InChI=1S/C22H26O5/c1-12(23)26-15-5-7-16-14(10-15)4-6-18-17(16)8-9-22(3)19(18)11-20(21(22)25)27-13(2)24/h5,7,10,17-20H,4,6,8-9,11H2,1-3H3/t17-,18-,19+,20-,22+/m1/s1; Key:QZQSENRWYLQIPC-JPVHLGFFSA-N;

Hydroxyestrone diacetate (brand names Colpoginon, Colpormon, Hormobion, Hormocervix) (former developmental code name RD-310), or 16α-hydroxyestrone diacetate, also known as 3,16α-dihydroxyestra-1,3,5(10)-trien-17-one 3,16α-diacetate, is a synthetic, steroidal estrogen which has been marketed in France, Spain, Brazil, and Argentina.^[1]^[2] It is a derivative of 16α-hydroxyestrone with an acetate esters attached at the C3 and C16α positions.^[1]

References

^ ^a ^b Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 531–. ISBN 978-3-88763-075-1.
^ Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. ISBN 978-3-527-30247-5.

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[IndexNominum2000-1] Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 531–. ISBN 978-3-88763-075-1.

[NegwerScharnow2001-2] Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. ISBN 978-3-527-30247-5.

[1]

[2]

See also

References