The Pangenome Gene Reference Resource (PGRR) is a comprehensive pangenome of the M. tuberculosis complex (MTBC), which spans all seven M. tuberculosis lineages and is produced using a virtually error-free sequencing and de novo assembly approach. It encompasses the complete panorama of genetic variation across all genes present in M. tuberculosis to provide an efficient tool for performing isolated gene alignments and for accessing gene-level information from the pangenome reference strains.

Poonam Chitale, Elissa Ocke, Aubrey R. Odom, Howard Fan, Alexander Henoch, Karla Vasco, Emily C. Fogarty, Courtney Grady, Alexander D. Lemenze, Pradeep Kumar, Shannon Manning, A. Murat Eren, W. Evan Johnson, and David Alland. Defining the Mycobacterium tuberculosis Pangenome and Suggestions for a New Composite Reference Sequence.